Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Robert J. Peach"'
Publikováno v:
European Journal of Immunology. 33:2074-2082
We used 5-(and 6-) carboxyfluorescein diacetate succinimidyl ester labeled TCR-transgenic CD4(+) T cells to investigate the contribution of B7 costimulation to T cell activation and clonal expansion. B7 costimulation was blocked with the fusion prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26dd47ebfa27139d02e73a2159ea185a
https://doi.org/10.1002/eji.200323929
https://doi.org/10.1002/eji.200323929
Publikováno v:
Infection and Immunity. 70:6940-6947
The ability of interleukin-10 (IL-10) to suppress accessory cell functions required for optimal T-cell activation makes it an important inhibitor of cell-mediated immunity. Thus, after infection with the protozoan parasiteToxoplasma gondii, IL-10 kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a086f2dd6e1c1fdad68b32f9174bf70
https://doi.org/10.1128/iai.70.12.6940-6947.2002
https://doi.org/10.1128/iai.70.12.6940-6947.2002
Publikováno v:
Cell Transplantation, Vol 11 (2002)
Previous work has demonstrated that short-term systemic administration of cytotoxic T lymphocyte antigen-4 (CTLA-4) Ig blocks human pancreatic islet xenograft rejection in mice and induces long-term, donor-specific tolerance, whereas studies on pig p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e085fc7e1e9e7af74a500b60f3c32185
https://doi.org/10.3727/000000002783985440
https://doi.org/10.3727/000000002783985440
Autor:
Andreas Knoflach, Laurence A. Turka, T. Mary E. Russell, Robert J. Peach, Rolando Milord, Mark D. Denton, Anil Chandraker, Kyung Soo Kim, Anna Maria Waaga, Mohamed H. Sayegh
Publikováno v:
The American Journal of Pathology. 158:977-986
Provision of adequate T cell costimulation is critical for the development of acute and chronic allograft rejection. We have previously reported that early blockade of CD28-B7 T cell costimulation prevents the development of graft arteriosclerosis, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c39e0bc97b87d2b0ca875ff1fb4b5839
https://doi.org/10.1016/s0002-9440(10)64044-8
https://doi.org/10.1016/s0002-9440(10)64044-8
Autor:
Robert J. Peach
Publikováno v:
Therapeutic Fc-Fusion Proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24d631193931165727ce2dc6ac71f51f
https://doi.org/10.1002/9783527675272.ch11
https://doi.org/10.1002/9783527675272.ch11
Autor:
James J. Mond, Robert J. Peach, Clifford M. Snapper, Andrew Lees, William C. Gause, Jerome Schartman, Yi Shen, Zheng-Qi Wu, Abdul Qadir Khan
Publikováno v:
The Journal of Immunology. 165:6840-6848
The requirements for B7 costimulation during an in vivo humoral response to an intact extracellular bacteria have not been reported. In this study we immunized mice with Streptococcus pneumoniae (R36A) to determine the B7 requirements for induction o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca416b9e36e7fa33c1179225dd3f236
https://doi.org/10.4049/jimmunol.165.12.6840
https://doi.org/10.4049/jimmunol.165.12.6840
Autor:
Wiltrud M. Kalka-Moll, Mohamed H. Sayegh, Francesca Stingele, Anil Chandraker, Arthur O. Tzianabos, Robert W. Finberg, Victor M. Dong, Robert J. Peach
Publikováno v:
Infection and Immunity. 68:6650-6655
Abscesses are a classic host response to infection by many pathogenic bacteria. The immunopathogenesis of this tissue response to infection has not been fully elucidated. Previous studies have suggested that T cells are involved in the pathologic pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f7a14097dd1cafa47c046aaaede900
https://doi.org/10.1128/iai.68.12.6650-6655.2000
https://doi.org/10.1128/iai.68.12.6650-6655.2000
Publikováno v:
European Journal of Immunology. 29:311-316
The B7 co-stimulatory pathway is critical to T cell activation, however its role in the generation of Th2 cells in vivo remains controversial. We have studied the role of B7 co-stimulation in the development of a Th2 immune response to the nematode p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be8da85150217c756447e5baf517626a
https://doi.org/10.1002/(sici)1521-4141(199901)29:01<311::aid-immu311>3.0.co
https://doi.org/10.1002/(sici)1521-4141(199901)29:01<311::aid-immu311>3.0.co
Publikováno v:
European Journal of Immunology. 26:401-408
In this report, we demonstrate that gp40, a molecule previously shown to be expressed by thymic epithelial cell lines in vitro and by thymic epithelial cells in vivo, is the murine homolog of human Ep-CAM, a calcium-independent homotypic adhesion mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b016876dbb0c57250908489c10fe3a
https://doi.org/10.1002/eji.1830260220
https://doi.org/10.1002/eji.1830260220
Autor:
Robert J. Peach, Peter S. Linsley
Publikováno v:
Methods. 8:116-123
CTLA-4 and CD28 are homologous T-cell surface receptors that associate with the B7-related counter receptors, B7-1 (CD80) and B7-2 (CD86), expressed on antigen-presenting cells. This association establishes the molecular basis for an important T-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e32ecf3a7d62620845d3995cf126920f
https://doi.org/10.1006/meth.1995.9995
https://doi.org/10.1006/meth.1995.9995