Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Robert J. Pauley"'
1
Data from Rad6B Is a Positive Regulator of β-Catenin Stabilization
Autor: Larry Tait, Bart O. Williams, Robert J. Pauley, Brigitte Gerard, Malathy P.V. Shekhar
Mutations in β-catenin or other Wnt pathway components that cause β-catenin accumulation occur rarely in breast cancer. However, there is some evidence of β-catenin protein accumulation in a subset of breast tumors. We have recently shown that Rad
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8f2d612e2bbc3bfcfecf9520deeaaf74
https://doi.org/10.1158/0008-5472.c.6497468
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3
Comedo-Ductal carcinoma in situ: A paradoxical role for programmed cell death
Autor: Hind Nassar, Gloria H. Heppner, Gen Sheng Wu, Pratima Nangia-Makker, Varun Shekhar, Malathy P.V. Shekhar, Larry Tait, Robert J. Pauley, Daniel W. Visscher, Fred R. Miller, Steven J. Santner
Publikováno v: Cancer Biology & Therapy. 7:1774-1782
Comedo-DCIS is a histologic subtype of preinvasive breast neoplasia that is characterized by prominent apoptotic cell death and has greater malignant potential than other DCIS subtypes. We investigated the mechanisms of apoptosis in comedo-DCIS and i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::684ce4a9d05b3b2ae3dcb5ef724991eb
https://doi.org/10.4161/cbt.7.11.6781
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4
Rad6B Is a Positive Regulator of β-Catenin Stabilization
Autor: Larry Tait, Malathy P.V. Shekhar, Brigitte Gerard, Bart O. Williams, Robert J. Pauley
Publikováno v: Cancer Research. 68:1741-1750
Mutations in β-catenin or other Wnt pathway components that cause β-catenin accumulation occur rarely in breast cancer. However, there is some evidence of β-catenin protein accumulation in a subset of breast tumors. We have recently shown that Rad
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99a6c3fb961c5b58719b7710b20bb81
https://doi.org/10.1158/0008-5472.can-07-2111
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5
Expression of transforming growth factor-β receptor type II and tumorigenicity in human breast adenocarcinoma MCF-7 cells
Autor: James K V Willson, Yong Ko, Wenhui Li, Elizabeth Zborowska, Herbert D. Soule, Sunandita S. Banerji, Robert J. Pauley, Yu Liu, Michael G. Brattain, Jiurong Liang
Publikováno v: Journal of Cellular Physiology. 176:424-434
To analyze transforming growth factor-beta (TGF-beta) response during MCF-7 cell progression, early passage (MCF-7E, 500 passage) cells were compared. MCF-7E cells showed an IC50 of approximately 10 ng/ml of TGF-beta1, whereas MCF-7L cells were insen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::48189de29f1e783e797afb2ddf4acade
https://doi.org/10.1002/(sici)1097-4652(199808)176:2<424::aid-jcp21>3.0.co
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6
Estrogen production via the aromatase enzyme in breast carcinoma: which cell type is responsible?
Autor: Ji-Ping Wang, Christopher W. Hamilton, Larry Tait, Robert J. Pauley, Jennifer R. Kaseta, Laurence M. Demers, Richard J. Santen, Steven J. Santner, Wei Yue
Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology. 61:267-271
Studies of breast tumor homogenates from women with breast cancer have demonstrated the synthesis of estrogens in situ through the enzyme aromatase. The present series of investigations sought to determine which cell type within the tumor is responsi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::12c533985fe731d06bde281c8af34929
https://doi.org/10.1016/s0960-0760(97)80022-2
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8
Aromatase Activity and Expression in Breast Cancer and Benign Breast Tissue Stromal Cells
Autor: Richard J. Santen, Robert J. Pauley, Larry Tait, Steven J. Santner, Jennifer R. Kaseta
Publikováno v: Journal of Clinical Endocrinology & Metabolism. 82:200-208
In situ estrogen synthesis by hormone-dependent breast cancers could potentially regulate cellular proliferation through autocrine or paracrine mechanisms. Several biochemical studies have demonstrated activity of the enzyme aromatase, the rate-limit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97aca04d65e697ddaf0fde344df8aebd
https://doi.org/10.1210/jc.82.1.200
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9
Xenograft Model of Progressive Human Proliferative Breast Disease
Autor: Robert J. Pauley, Gloria H. Heppner, Larty Tait, Fred R. Miller, Sandra R. Wolman, Herbert D. Soule, Peter J. Dawson
Publikováno v: JNCI Journal of the National Cancer Institute. 85:1725-1732
Background Progression of proliferative breast disease has been associated with increased risk for development of invasive carcinoma. Cell lines have been developed to facilitate the study of this process. Human cell line MCF10A originated from spont
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936c9c1173915509790227a11834088a
https://doi.org/10.1093/jnci/85.21.1725
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10
A new infectious mammary tumor virus in the milk of mice implanted with C4 hyperplastic alveolar nodules
Autor: Hong Wang, Hans Acha-Orbea, A N Shakhov, Wei Zen Wei, Robert J. Pauley
Publikováno v: European Journal of Immunology. 23:2765-2769
We have previously characterized an infectious mouse mammary tumor virus [(MMTV(SW)] which induces a strong superantigen response in vivo. Here we describe the isolation and characterization of MMTV(C4) which was derived from milk of mice implanted w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::535a91baf1e53ffa8fa400e717e0fca7
https://doi.org/10.1002/eji.1830231107
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