Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Robert J. Ono"'
Autor:
Cecilia G Martin, Alshakim Nelson, Trevor G. Johnston, Dylan G Karis, Steven M Adelmund, Ryan T. Shafranek, Robert J. Ono, Christopher R. Fellin, Cole A. DeForest
Publikováno v:
Polymer International. 68:1238-1246
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a23e2814610da972c2e76c02e805fbc5
https://doi.org/10.1002/pi.5716
https://doi.org/10.1002/pi.5716
Autor:
Zhi Xiang Voo, Yi Yan Yang, Shujun Gao, Robert J. Ono, Ashlynn L. Z. Lee, Chuan Yang, James L. Hedrick, Willy Chin
Publikováno v:
ACS Applied Materials & Interfaces. 10:13274-13282
In this study, bortezomib (BTZ, a cytotoxic water-insoluble anticancer drug) was encapsulated in micellar nanoparticles having a catechol-functionalized polycarbonate core through a pH-sensitive covalent bond between phenylboronic acid (PBA) in BTZ a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9e8959eb1f4b9e6e6441b6e88a35fda
https://doi.org/10.1021/acsami.7b14319
https://doi.org/10.1021/acsami.7b14319
Autor:
Robert J. Ono, Michelle Ng, Kiran Kumar, Zhen Chang Liang, Lanjuan Li, Huihui Dong, Mareva Fevre, Shaoqiong Liu, Jackie Y. Ying, Yi Yan Yang, Ashlynn L. Z. Lee, Zhongkang Ji, Jye Yng Teo, Chuan Yang, Hong Wu, Shujun Gao, Musan Zhang, Jeremy P. K. Tan, Chang Bao, James L. Hedrick, Weimin Fan, Guansheng Zhong, Kaijin Xu, Julian M. W. Chan
Publikováno v:
Biomaterials. 127:36-48
Effective antimicrobial agents are important arsenals in our perennial fight against communicable diseases, hospital-acquired and surgical site multidrug-resistant infections. In this study, we devise a strategy for the development of highly efficaci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b566b21953ddfc292e0159259acd7bc6
https://doi.org/10.1016/j.biomaterials.2017.02.027
https://doi.org/10.1016/j.biomaterials.2017.02.027
Autor:
Duane W. Storti, Alshakim Nelson, Ankit Vora, Robert J. Ono, Musan Zhang, Mark A. Ganter, Dylan G Karis
Publikováno v:
Polymer Chemistry. 8:4199-4206
Triple stimuli-responsive ABA triblock copolymer hydrogels composed of poly(allyl glycidyl ether)-stat-poly(alkyl glycidyl ether)-block-poly(ethylene glycol)-block-poly(allyl glycidyl ether)-stat-poly(alkyl glycidyl ether) were synthesized using cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e97ec140862e17da13d9a7690085807
https://doi.org/10.1039/c7py00831g
https://doi.org/10.1039/c7py00831g
Publikováno v:
ACS Macro Letters. 5:1247-1252
Postpolymerization modification is a critical strategy for the development of functional polycarbonate scaffolds for medicinal applications. To expand the scope of available postpolymerization functionalization methods, polycarbonates containing pend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90d35abe2f2fe3a86ec8f634744899a
https://doi.org/10.1021/acsmacrolett.6b00705
https://doi.org/10.1021/acsmacrolett.6b00705
Autor:
Wei Cheng, Ulrich S. Schubert, Mareva Fevre, Xiyu Ke, Rudy J. Wojtecki, Robert J. Ono, James L. Hedrick, Qingxing Xu, Yi Yan Yang, Christoph Englert, Kristian Kempe, Jeannette M. Garcia, Chuan Yang, Matthias Hartlieb
Publikováno v:
Polymer Chemistry. 7:5862-5872
Commercially-available linear and branched PEIs (LPEI and BPEI) were chemically-modified with carbohydrates and carbohydrate-mimetics to improve biocompatibility. Hydroxyl moieties were installed in a close proximity via reaction of PEI's amines with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fd916fde0bc591aa51a5cc029f85c43
https://doi.org/10.1039/c6py00940a
https://doi.org/10.1039/c6py00940a
Autor:
Jordan Yong Ming Tan, Shujun Gao, Shaoqiong Liu, Robert J. Ono, Yi Yan Yang, James L. Hedrick, Chuan Yang
Publikováno v:
ACS applied materialsinterfaces. 10(23)
To exploit tumor and intracellular microenvironments, pH-responsive diblock copolymers of poly(ethylene glycol) and catechol-functionalized polycarbonate with acid-labile acetal bond as the linker are synthesized to prepare micellar nanoparticles tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef82cc92c68e25573fa9bac67bd92ea
https://pubmed.ncbi.nlm.nih.gov/29757607
https://pubmed.ncbi.nlm.nih.gov/29757607
Autor:
Robert J. Ono, Christoph Englert, Xiyu Ke, Rudy J. Wojtecki, James L. Hedrick, Chuan Yang, Kristian Kempe, Ulrich S. Schubert, Swee Kwang Chu, Peter Bellstedt, Jeannette M. Garcia, Mareva Fevre, Matthias Hartlieb, Yi Yan Yang
Publikováno v:
Macromolecules. 48:7420-7427
(Bio)degradable poly(ethylene imine-co-glycine)s (P(EI-co-Gly)) were synthesized through efficient and controlled oxidation of linear poly(ethylene imine) (LPEI) using hydrogen peroxide in a methanol/water mixture. Temperature, peroxide concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9aed037793690b851e081167cd69e49
https://doi.org/10.1021/acs.macromol.5b01940
https://doi.org/10.1021/acs.macromol.5b01940
Autor:
Wei Sheng Goh, Robert J. Ono, James L. Hedrick, Willy Chin, Ashlynn L. Z. Lee, Amelia Y. L. Lee, Yi Yan Yang
Publikováno v:
ACS Macro Letters. 4:886-891
Biodegradable polycarbonate-based ABA triblock copolyelectrolytes were synthesized and formulated into physically cross-linked hydrogels. These biocompatible, cationically, and anionically charged hydrogel materials exhibited pronounced shear-thinnin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7398d90cfca45978e17a4b782f7eff49
https://doi.org/10.1021/acsmacrolett.5b00527
https://doi.org/10.1021/acsmacrolett.5b00527
Autor:
Alshakim Nelson, Daniel J. Coady, Xiyu Ke, Robert J. Ono, Roy Lubbers, Julian M. W. Chan, Yi Yan Yang, Shujun Gao, James L. Hedrick, Amanda C. Engler
Publikováno v:
Macromolecules. 48:1673-1678
Poly(ethylene glycol) (PEG) represents the gold standard for stealth polymers in polymer-based therapeutic delivery. Unfortunately, PEG has some limitations which warrant the examination of alternative polymers. High molecular weight PEG (>40 kDa) ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::289369ccf129397ab9db2bcedeeb9f37
https://doi.org/10.1021/acs.macromol.5b00156
https://doi.org/10.1021/acs.macromol.5b00156