Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Robert J. M. Kurzeja"'
Autor:
E Allen Sickmier, Robert J M Kurzeja, Klaus Michelsen, Mukta Vazir, Evelyn Yang, Andrew S Tasker
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163366 (2016)
Panitumumab and cetuximab target the epidermal growth factor receptor for the treatment of metastatic colorectal cancer. These therapies provide a significant survival benefit to patients with metastatic colorectal cancer with wild-type RAS. A single
Externí odkaz:
https://doaj.org/article/9714291c953e4ed38fccb50a2c3b5208
Autor:
Juraj Svitel, Han Xu, Jennifer L. Lippens, Joseph A. Loo, Robert J. M. Kurzeja, Iain Campuzano, Dhanashri Bagal, Paul D. Schnier, Huilin Li
Publikováno v:
Analytical Chemistry. 88:12427-12436
Over the past two decades orthogonal acceleration time-of-flight has been the de facto analyzer of choice for solution and membrane soluble protein native mass spectrometry (MS) studies; this however is gradually changing. Here we compare three MS in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6a76b641858679d87bb981caae8ad5
https://doi.org/10.1021/acs.analchem.6b03762
https://doi.org/10.1021/acs.analchem.6b03762
Autor:
Kate S, Ashton, Kristin L, Andrews, Marian C, Bryan, Marion C, Bryan, Jie, Chen, Kui, Chen, Michelle, Chen, Samer, Chmait, Michael, Croghan, Rod, Cupples, Christopher, Fotsch, Joan, Helmering, Steve R, Jordan, Robert J M, Kurzeja, Klaus, Michelsen, Lewis D, Pennington, Steve F, Poon, Glenn, Sivits, Gwyneth, Van, Steve L, Vonderfecht, Robert C, Wahl, Jiandong, Zhang, David J, Lloyd, Clarence, Hale, David J, St Jean
Publikováno v:
Journal of Medicinal Chemistry. 57:309-324
Small molecule activators of glucokinase have shown robust efficacy in both preclinical models and humans. However, overactivation of glucokinase (GK) can cause excessive glucose turnover, leading to hypoglycemia. To circumvent this adverse side effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::688eef24bebd019f68813ef22be87641
https://doi.org/10.1021/jm4016735
https://doi.org/10.1021/jm4016735
Autor:
Kate S. Ashton, Kristin L. Andrews, Marian C. Bryan, Jie Chen, Kui Chen, Michelle Chen, Samer Chmait, Michael Croghan, Rod Cupples, Christopher Fotsch, Joan Helmering, Steve R. Jordan, Robert J. M. Kurzeja, Klaus Michelsen, Lewis D. Pennington, Steve F. Poon, Glenn Sivits, Gwyneth Van, Steve L. Vonderfecht, Robert C. Wahl, Jiandong Zhang, David J. Lloyd, Clarence Hale, David J. St. Jean
Publikováno v:
Journal of Medicinal Chemistry. 57:2820-2820
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca5bcfb2fb26be4d19b7688158bfd6e6
https://doi.org/10.1021/jm500248d
https://doi.org/10.1021/jm500248d
Autor:
Sickmier, E. Allen1 sickmier@amgen.com, Kurzeja, Robert J. M.2, Michelsen, Klaus1, Vazir, Mukta3, Yang, Evelyn3, Tasker, Andrew S.3
Publikováno v:
PLoS ONE. 9/22/2016, Vol. 11 Issue 9, p1-11. 11p.
Publikováno v:
Cancer Weekly; 1/30/2024, p440-440, 1p
Autor:
Chen, Kui, Michelsen, Klaus, Kurzeja, Robert J. M., Han, Joon, Vazir, Mukta, St. Jean, David J., Hale, Clarence, Wahl, Robert C.
Publikováno v:
Journal of Biomolecular Screening; Aug2014, Vol. 19 Issue 7, p1014-1023, 10p
Autor:
Killion, Elizabeth A., Wang, Jinghong, Yie, Junming, Shi, Stone D.-H., Bates, Darren, Min, Xiaoshan, Komorowski, Renee, Hager, Todd, Deng, Liying, Atangan, Larissa, Lu, Shu-Chen, Kurzeja, Robert J. M., Sivits, Glenn, Lin, Joanne, Chen, Qing, Wang, Zhulun, Thibault, Stephen A., Abbott, Christina M., Meng, Tina, Clavette, Brandon
Publikováno v:
Science Translational Medicine; 12/19/2018, Vol. 10 Issue 472, pN.PAG-N.PAG, 1p