Zobrazeno 1 - 10 of 19 pro vyhledávání: '"Robert J. Kuchler"'
1
Altered Amphibian Cell Morphology Following Treatment with Polyene Antibiotic and a Mammalian RNA Virus
Autor: Carl P. Schaffner, Paul B. Fisher, Robert J. Kuchler, Vernon Bryson, Witold Mechlinski, Daniel P. Bonner
Publikováno v: Experimental Biology and Medicine. 146:1122-1127
SummaryPolyene antibiotics are agents known to damage cell membranes. The hexaene antibiotic, mediocidin, was used in an attempt to introduce a mammalian virus (Mengo) into normally nonpermissive ICR 2A haploid frog cells. Although no infectious viru
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0306675177900b865f099465db7ef37b
https://doi.org/10.3181/00379727-146-38258
Zobrazit plný text záznamu
2
Identification of a rosette-enriched chromatin fraction from mouse fibroblast nuclei
Autor: Carl A. Ascoli, Stanley Mandeles, Nancy Venturo, Robert J. Kuchler, Marianne R. Link
Publikováno v: Archives of Biochemistry and Biophysics. 263:334-348
We have characterized two components of DNA isolated from mouse L-M cell nuclei. These components, designated as HMW (high molecular weight) and VHMW (very high molecular weight) DNA, were characterized by rate zonal sedimentation, agarose gel electr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ee18e23e78cd7ff7600df725a0df06
https://doi.org/10.1016/0003-9861(88)90644-3
Zobrazit plný text záznamu
3
Affinity chromatography purification of diphtheria toxin
Autor: Robert J. Kuchler, George Cukor, Josephine D. Readio
Publikováno v: Biotechnology and Bioengineering. 16:925-931
NAD was covalently linked to Sepharose-4B using a 6 carbon spacer. Sterile, dialyzed spent culture medium containing 100 Lf/ml of diphtheria toxin or material concentrated by (NH4)2SO4 precipitation containing 1500 Lf/ml, was chromatographed on a col
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee76c519eea4871471f7068e7ed33d7c
https://doi.org/10.1002/bit.260160706
Zobrazit plný text záznamu
4
THE RESPONSE OF CULTURED MAMMALIAN CELLS TO DIPHTHERIA TOXIN
Autor: Robert J. Kuchler, Thomas J. Moehring, J M Moehring, Morris Solotorovsky
Publikováno v: Journal of Experimental Medicine. 126:407-422
The response to diphtheria toxin of two sensitive cell lines, KB and HeLa, was investigated. Inhibition of the incorporation of radioactively labeled amino acids into protein was the earliest detectable effect of diphtheria toxin. It was observed tha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7c477535b40e9e9953908ef00051c79e
https://doi.org/10.1084/jem.126.3.407
Zobrazit plný text záznamu
5
Estradiol-Cellular Interaction in Tissue Culture
Autor: Robert C. Grauer, Robert J. Kuchler, Nancy J. Arnold
Publikováno v: Experimental Biology and Medicine. 111:798-804
SummaryL strain fibroblasts were grown in medium 199P containing estrone-16-C14 and estradiol-16-C14 at a concentration ranging from 10-7 to 10-5 M. These cells did not convert either steroid into water soluble conjugates in 72 hours. The estradiol i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad26f5ac63acb31900048ca36dfe669
https://doi.org/10.3181/00379727-111-27926
Zobrazit plný text záznamu
6
Biological Activity of Heated Diphtheria Toxin
Autor: Morris Solotorovsky, George Cukor, Robert J. Kuchler
Publikováno v: Journal of Bacteriology. 115:277-283
Diphtheria toxin splits into two fragments when heated at 100 C for 10 min in a phosphate buffer. The separated fragments have molecular weights of 24,000 and 39,000, respectively. These molecular weights are similar to those of the A and B fragments
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ffb5484199434a0c1e15b4ff855b1c
https://doi.org/10.1128/jb.115.1.277-283.1973
Zobrazit plný text záznamu
7
The role pf sodium and potassium in regulating amino acid accumulation and protein synthesis in LM-strain mouse fibroblasts
Autor: Robert J. Kuchler
Publikováno v: Biochimica et Biophysica Acta (BBA) - General Subjects. 136:473-483
The effect of varying the Na + to K + ratio has been studied in relation to the regulation of amino acid accumulation, protein synthesis and cell growth in LM-strain mouse fibroblasts. Amino acid accumulation and protein synthesis in these cells was
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0fe26b71003b89dc4425bb5d15147b
https://doi.org/10.1016/0304-4165(67)90006-2
Zobrazit plný text záznamu
8
The Relationship Between Cytotoxicity and Interferon Induction in L-M Strain Mouse Fibroblasts
Autor: Robert J. Kuchler, S. S. Asculai
Publikováno v: Experimental Biology and Medicine. 143:252-255
SummaryThe incidence of cell damage in L-M cell cultures exposed to DEAE-dextran increased with an increase in the concentration of the polycation. Poly I:C alone exerted a toxic effect which could be neutralized by 10 μg DEAE-dextran/ml. Cytotoxici
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f38a73f4adc50d0ae3dc7ab7eacd87ad
https://doi.org/10.3181/00379727-143-37297
Zobrazit plný text záznamu
10
The inhibition of virus adsorption by substances induced by DEAE-dextran and poly I:C
Autor: Robert J. Kuchler, S. S. Asculai, A B Kupferberg
Publikováno v: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 145(3)
SummaryThe adsorption of mengovirus to L-M cells is inhibited either directly by DEAE-dextran or by substances released into culture media from cells exposed to DEAE-dextran and DEAE-dextran combined with poly I:C. Therefore, preparations containing
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48269bfbd1b419f584d2880e8a0e9419
https://pubmed.ncbi.nlm.nih.gov/4362008
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje