Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Robert J. Klaassen"'
Autor:
David A. Andrae, Rachael F. Grace, Adrian Jewett, Brandon Foster, Robert J. Klaassen, Sam Salek, Junlong Li, Feng Tai, Audra N. Boscoe, Erin Zagadailov
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 7, Iss 1, Pp 1-11 (2023)
Abstract Background Pyruvate kinase (PK) deficiency is a rare hereditary disorder characterized by chronic hemolytic anemia and serious sequalae which negatively affect patient quality of life. This study aimed to psychometrically validate the first
Externí odkaz:
https://doaj.org/article/f607b4e929e24ad3b4e8b6a8b9dc0dbe
Autor:
Philippos Klonizakis, Noémi Roy, Ioanna Papatsouma, Maria Mainou, Ioanna Christodoulou, Despina Pantelidou, Smaro Kokkota, Michael Diamantidis, Alexandra Kourakli, Vasileios Lazaris, Dimitrios Andriopoulos, Apostolos Tsapas, Robert J. Klaassen, Efthymia Vlachaki
Publikováno v:
Healthcare, Vol 12, Iss 5, p 524 (2024)
The assessment of health-related quality of life (HRQoL) in thalassemia offers a holistic approach to the disease and facilitates better communication between physicians and patients. This study aimed to evaluate the HRQoL of transfusion-dependent th
Externí odkaz:
https://doaj.org/article/2b7b58604d1546f0b53387bbf45a0f12
Autor:
Jae-Yung Kwon, Lara Russell, Theresa Coles, Robert J. Klaassen, Kara Schick-Makaroff, Kathryn M. Sibley, Sandra A. Mitchell, Richard Sawatzky
Publikováno v:
Current Oncology, Vol 29, Iss 5, Pp 3093-3103 (2022)
Tools for measuring patients’ perceived health and quality of life, such as patient-reported outcome measures (PROMs), inform clinical decisions for patients requiring radiation therapy. However, there may be inconsistencies in how patients interpr
Externí odkaz:
https://doaj.org/article/31e76bfd87f74143b179f72bbfe18670
Autor:
Sara D. Khangura, Beth K. Potter, Christine Davies, Robin Ducharme, A. Brianne Bota, Steven Hawken, Kumanan Wilson, Maria D. Karaceper, Robert J. Klaassen, Julian Little, Ewurabena Simpson, Pranesh Chakraborty
Publikováno v:
BMC Pediatrics, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Newborn screening (NBS) for sickle cell disease incidentally identifies heterozygous carriers of hemoglobinopathy mutations. In Ontario, Canada, these carrier results are not routinely disclosed, presenting an opportunity to inves
Externí odkaz:
https://doaj.org/article/55c9436047534d04b6dc6dcd133ce96f
Autor:
Victoria E. Price, Saunya Dover, Victor S. Blanchette, Robert J. Klaassen, Mark Belletrutti, Aisha A. K. Bruce, Anthony K. Chan, Cindy Wakefield, Manuel Carcao, Vanessa Bouskill, Nancy L. Young
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 3, Pp 403-411 (2021)
Abstract Introduction The purpose of this study was to review and update the content of the Canadian Hemophilia Outcomes–Kids’ Life Assessment Tool version 2.0 (CHO‐KLAT), in the context of extended half‐life (EHL) factor concentrates (FCs) a
Externí odkaz:
https://doaj.org/article/b7155b73d40f43dbbc3657f20b7fa57c
Autor:
Saunya Dover, Victor S. Blanchette, Darius Wrathall, Eleanor Pullenayegum, Daniel Kazandjian, Byron Song, Sue Ann Hawes, Stéphanie Cloutier, Geroges E. Rivard, Robert J. Klaassen, Elizabeth Paradis, Nicole Laferriere, Ann Marie Stain, Anthony K. Chan, Sara J. Israels, Roona Sinha, MacGregor Steele, John K. M. Wu, Brian M. Feldman
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 2, Pp 318-325 (2020)
Abstract Background Standard of care for persons with severe hemophilia A includes regular replacement of factor VIII (FVIII). Prophylaxis regimens using standard half‐life (SHL) FVIII concentrates, while effective, are costly and require frequent
Externí odkaz:
https://doaj.org/article/abd4dde1d5e44b079b95eefa7c063dbe
Autor:
Jennifer Stimec, Saunya Dover, Eleanor Pullenayegum, Victor S. Blanchette, Andrea S. Doria, Brian M. Feldman, Manuel Carcao, Georges E. Rivard, Sara J. Israels, Anthony K. Chan, MacGregor Steele, Stephanie Cloutier, Robert J. Klaassen, Victoria E. Price, Roona Sinha, Nicole Laferriere, Elizabeth Paradis, John K. M. Wu, Paul Babyn
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 7, Pp n/a-n/a (2021)
Abstract Background This study examined the structural outcomes for joints of boys with severe hemophilia A receiving frequency/dose‐escalated primary prophylaxis using magnetic resonance imaging (MRI), and the importance of interval MRI changes. M
Externí odkaz:
https://doaj.org/article/68fbd9e419e743b5a680bc936b57aeb5
Autor:
Haowei (Linda) Sun, Ming Yang, Man‐Chiu Poon, Adrienne Lee, K. Sue Robinson, Michelle Sholzberg, John Wu, Alfonso Iorio, Victor Blanchette, Manuel Carcao, Robert J. Klaassen, Shannon Jackson
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 7, Pp n/a-n/a (2021)
Abstract Background Recombinant factors VIII and IX Fc (rFVIIIFc/rFIXFc) were the only available extended half‐life (EHL) products in Canada during 2016 to 2018. Objectives To evaluate if patient‐reported outcome measures (PROMs) improved in Cana
Externí odkaz:
https://doaj.org/article/cdf7d3770049495c886f6d00d200190b
Autor:
Saunya Dover, Nancy L. Young, Victor S. Blanchette, Robert J. Klaassen, Anthony K. Chan, Cindy Wakefield, Vanessa Bouskill, Manuel Carcao, Mark Belletrutti, Aisha A. K. Bruce, Victoria E. Price
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 4, Pp n/a-n/a (2021)
Abstract Introduction This study aimed to assess the impact of hemophilia on families, in the context of current and emerging hemostatic therapies, and explore the need for a hemophilia‐specific tool targeted at parents of boys aged
Externí odkaz:
https://doaj.org/article/de09755659b04ce78dee22f6bf023bf0
Autor:
Nicolas Waespe, Santhosh Dhanraj, Manju Wahala, Elena Tsangaris, Tom Enbar, Bozana Zlateska, Hongbing Li, Robert J. Klaassen, Conrad V. Fernandez, Geoff D. E. Cuvelier, John K. Wu, Yves D. Pastore, Mariana Silva, Jeffrey H. Lipton, Joseé Brossard, Bruno Michon, Sharon Abish, MacGregor Steele, Roona Sinha, Mark J. Belletrutti, Vicky R. Breakey, Lawrence Jardine, Lisa Goodyear, Liat Kofler, Michaela Cada, Lillian Sung, Mary Shago, Stephen W. Scherer, Yigal Dror
Publikováno v:
npj Genomic Medicine, Vol 2, Iss 1, Pp 1-8 (2017)
Blood disorders: impact of genomic structural variation Copy number variation in patients with inherited bone marrow failure syndromes (IBMFSs) is associated with more severe clinical symptoms. In addition to persistently low levels of red blood cell
Externí odkaz:
https://doaj.org/article/fab055366f7246f79c31483ee2eaa142