Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Robert J. Kays"'
Autor:
Eduard F. Stange, Charles L. Bevins, Guoxing Wang, Robert J. Kays, Jan Wehkamp, Oliver Burk, Klaus Fellermann, Hans Clevers, Alex Gregorieff, Matthias Schwab, Anke Schnabel, Irmgard Kübler, Sabine Nuding
Publikováno v:
The Journal of Immunology. 179:3109-3118
Ileal Crohn′s disease (CD), a chronic mucosal inflammation, is characterized by two pertinent features: a specific decrease of Paneth cell-produced antimicrobial α-defensins and the presence of mucosal-adherent bacteria. A mutation in NOD2, the mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d96ecc683f248a0c2824c41f65ba942
https://doi.org/10.4049/jimmunol.179.5.3109
https://doi.org/10.4049/jimmunol.179.5.3109
Autor:
Xiping Xu, Ashley I. Yudin, C. L. Bevins, Theodore L. Tollner, Scott A. Venners, Robert J. Kays, Genfu Tang, James W. Overstreet, Tsang Lau, Edward J. Hollox, Xue Liu, Houxun Xing, Gary N. Cherr
Publikováno v:
Science Translational Medicine. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c4950025d1c4f1204618e96fb458a01
https://doi.org/10.1126/scitranslmed.3009423
https://doi.org/10.1126/scitranslmed.3009423
Autor:
Ashley I. Yudin, C. L. Bevins, Edward J. Hollox, James W. Overstreet, Genfu Tang, Xiping Xu, Scott A. Venners, Xue Liu, Houxun Xing, Robert J. Kays, Tsang Lau, Theodore L. Tollner, Gary N. Cherr
Publikováno v:
Science Translational Medicine. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1acd228e55340edee92fb8ed74369554
https://doi.org/10.1126/scitranslmed.3002953
https://doi.org/10.1126/scitranslmed.3002953
Autor:
Robert J. Kays, Xue Liu, Tsang Lau, Houxun Xing, Xiping Xu, Genfu Tang, Ashley I. Yudin, James W. Overstreet, Charles L. Bevins, Theodore L. Tollner, Gary N. Cherr, Edward J. Hollox, Scott A. Venners
Publikováno v:
Science Translational Medicine. 3
A glycosylated polypeptide, β-defensin 126 (DEFB126), derived from the epididymis and adsorbed onto the sperm surface, has been implicated in immunoprotection and efficient movement of sperm in mucosal fluids of the female reproductive tract. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59549d04abbe948a4cc5bc8723d107a5
https://doi.org/10.1126/scitranslmed.3002289
https://doi.org/10.1126/scitranslmed.3002289
Autor:
Charles L. Bevins, Robert J. Kays, James W. Overstreet, Gary N. Cherr, Cathy A. Treece, Theodore L. Tollner, Ashley I. Yudin
Publikováno v:
Reproduction (Cambridge, England). 136(6)
Surface components of sperm isolated from the cauda epididymides were stabilized by whole sperm fixation for immunization of rabbits. The resulting immunoglobulins (Igs) recognized a single protein of 130 kDa (non-reduced) or 54–57 kDa (reduced) on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1a36e4d770daecfb556879016f7710
https://pubmed.ncbi.nlm.nih.gov/18787081
https://pubmed.ncbi.nlm.nih.gov/18787081
Autor:
Michael D. George, Christian M. Leutenegger, Irina Grishina, Satya Dandekar, Sadiah Sabir, Jan Wehkamp, Robert J. Kays, Charles L. Bevins
Publikováno v:
BMC genomics, vol 9, iss 1
BMC Genomics
BMC Genomics, Vol 9, Iss 1, p 209 (2008)
BMC Genomics
BMC Genomics, Vol 9, Iss 1, p 209 (2008)
Background The small intestinal epithelium mediates vital functions of nutrient absorption and host defense. The spatial organization of the epithelial cells along the crypt-villus axis segregates them into regions of specialized function. However, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b696dc8dc420eb8fa85953bc59fff575
https://escholarship.org/uc/item/28t3907g
https://escholarship.org/uc/item/28t3907g
Autor:
Charles L. Bevins, Robert J. Kays, Jennifer L. Huff, Don R. Canfield, Michael Hornsby, Jay V. Solnick
Background & Aims: We used the rhesus macaque model to study the effects of the cag pathogenicity island ( cag PAI) on the H pylori host-pathogen interaction. Methods: H pylori– specific pathogen-free (SPF) monkeys were experimentally challenged wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::facc4b4232cc70eb1c334f5f7960cecb
https://europepmc.org/articles/PMC2386437/
https://europepmc.org/articles/PMC2386437/
Autor:
Kyle Kusek, Robert J. Kays, Jaya Punati, John A. Barnard, Laura M. Mackner, Hiutung Chu, Wallace Crandall, Charles L. Bevins
Publikováno v:
Gastroenterology. 136:A-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::085894d6b8b09e65f58322104e3dd799
https://doi.org/10.1016/s0016-5085(09)60067-6
https://doi.org/10.1016/s0016-5085(09)60067-6
Regional variations in Paneth cell antimicrobial peptide expression along the mouse intestinal tract
Autor:
Mats Andersson, Robert J. Kays, Hiutung Chu, Katrin Pütsep, Charles L. Bevins, Jenny Karlsson
Publikováno v:
BMC immunology, vol 9, iss 1
BMC Immunology, Vol 9, Iss 1, p 37 (2008)
BMC Immunology
BMC Immunology, Vol 9, Iss 1, p 37 (2008)
BMC Immunology
Background Enteric antimicrobial peptides secreted from Paneth cells, including α-defensins (in mice named cryptdins), are key effector molecules of innate immunity in the small intestine. The importance of Paneth cells α-defensins emerged from stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2913e56bc5144f70e03fd229b019de26
https://doi.org/10.1186/1471-2172-9-37
https://doi.org/10.1186/1471-2172-9-37
Autor:
Ryan W. Feathers, Robert J. Kays, Bo Shen, Jan Wehkamp, Charles L. Bevins, Sarah K. Lee, Hiutung Chu
Publikováno v:
FEBS Letters. (22):5344-5350
Antimicrobial peptides and proteins are key effectors of innate immunity, expressed both by circulating phagocytic cells and by epithelial cells of mucosal tissues. In the human small intestine, Paneth cells are secretory epithelial cells that expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43208d507aa74587a8c756bb44ba0eac