Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Robert J. Kahn"'
Autor:
Michel Goldman, Stanislaw Jankowski, Robert J. Kahn, Arnaud Marchant, Jean Louis Vincent, Gilberto Friedman
Publikováno v:
Journal of Critical Care. 12:183-187
The aim of this study was to investigate the relation between interleukin (IL) 10, tumor necrosis factor alpha (TNF alpha), IL-1, and IL-6 levels in patients with septic shock and relate these cytokine levels to the development of organ failure.In 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55692408333a7f7e9cca6b985ea2bcf
https://doi.org/10.1016/s0883-9441(97)90030-7
https://doi.org/10.1016/s0883-9441(97)90030-7
Autor:
Jacques Berré, Robert J. Kahn, Jean-Jacques Moraine, Jean Louis Vincent, Christian Melot, Daniel De Backer
Publikováno v:
Critical Care Medicine. 25:392-398
To evaluate the effects of dobutamine on cerebral hemodynamics in septic patients with stable hemodynamic status.Open-label, prospective study.Multidisciplinary department of intensive care in a university hospital.Fourteen mechanically ventilated se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad9ec8a080947cefd6284d5289310590
https://doi.org/10.1097/00003246-199703000-00004
https://doi.org/10.1097/00003246-199703000-00004
Publikováno v:
Intensive Care Medicine. 22:404-408
Both serum levels of tumor necrosis factor-alpha (TNF alpha) and interleukin-6 (IL-6) and blood lactate levels in patients with septic shock have been shown to correlate with prognosis. The aim of the study was to define the relative predictive value
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab97a0a2ae64105bfb248fc5dc2a65fa
https://doi.org/10.1007/bf01712155
https://doi.org/10.1007/bf01712155
Autor:
Robert J. Kahn, Gilberto Friedman, Michel Goldman, Mohammad Shahla, Jean Louis Vincent, Stanislaw Jankowski, Richard M. Rose
Publikováno v:
Critical Care Medicine. 24:229-233
Objectives : To determine the safety and pharmacokinetics of a murine monoclonal antibody to E-selectin in patients with newly developed septic shock. Design : Open-label, prospective, phase II pilot study with escalating doses of the antibody. Setti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b15922323f40446a24f321fd81f23d
https://doi.org/10.1097/00003246-199602000-00008
https://doi.org/10.1097/00003246-199602000-00008
Publikováno v:
Intensive Care Medicine. 21:838-841
The prevalence of hypocalcaemia is known to be elevated in critically ill patients, but the expected benefit from calcium repletion in hypocalcaemic patients has not been well defined. The objective of the present study was therefore prospective dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1299e3d28dc00e7de6183c6271268f
https://doi.org/10.1007/bf01700968
https://doi.org/10.1007/bf01700968
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 150:95-100
Dobutamine has been proposed as a means of disclosing a pathologic oxygen supply (DO2) dependency in critically ill patients. Like other catecholamines, however, dobutamine might increase cellular metabolism, so that oxygen consumption (VO2) would in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950baa253ac8f74cab508b40f67895c2
https://doi.org/10.1164/ajrccm.150.1.8025780
https://doi.org/10.1164/ajrccm.150.1.8025780
Publikováno v:
Critical Care Medicine. 21:1658-1664
OBJECTIVE To compare the effects of prostacyclin (PGI2) and dobutamine on the relationship between oxygen delivery (DO2) and oxygen uptake (VO2) in stable septic patients. DESIGN Prospective study using a crossover design with alternate order of medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9de932dc41597e8d7a071a5a4c58d107
https://doi.org/10.1097/00003246-199311000-00014
https://doi.org/10.1097/00003246-199311000-00014
Autor:
Maria-Luisa Alegre, Michael R. Pinsky, Etienne Dupont, Robert J. Kahn, Jean Louis Vincent, Jacques Devière
Publikováno v:
Chest. 103:565-575
Purpose : Cytokines have been associated with the development of sepsis and diffuse tissue injury following septic or endotoxic challenges in humans. Furthermore, relative organ-system dysfunction, not specific organ dysfunction, appears to predict o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bd8826277d7bfc9aecbcbba51fc0a9d
https://doi.org/10.1378/chest.103.2.565
https://doi.org/10.1378/chest.103.2.565
Publikováno v:
Europe PubMed Central
OBJECTIVE To assess the hemodynamic effects of the addition of small bolus doses of the phosphodiesterase inhibitor enoximone to adrenergic therapy in patients with severe heart failure. DESIGN Open label, prospective study. SETTING Multidisciplinary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbcf0f5fd634ab9c7d6e0c6353f1257
https://doi.org/10.1097/00003246-199208000-00006
https://doi.org/10.1097/00003246-199208000-00006
Autor:
Jan Bakker, Gaëtan Marecaux, Jean Louis Vincent, Liliane Schandene, Robert J. Kahn, Etienne Dupont
Publikováno v:
Chest. 101:810-815
In this pilot study, murine monoclonal anti-TNF antibody (2 mg/kg) was administered to ten patients within 24 h of septic shock which persisted after initial resuscitation with intravenous fluids and adrenergic agents. This treatment resulted in a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8d58620cb696dc823d64d4379107317
https://doi.org/10.1378/chest.101.3.810
https://doi.org/10.1378/chest.101.3.810