Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Robert J. Ingham"'
Publikováno v:
Experimental Hematology & Oncology, Vol 10, Iss 1, Pp 1-12 (2021)
Abstract Classical Hodgkin lymphoma (cHL) and anaplastic lymphoma kinase-positive, anaplastic large cell lymphoma (ALK+ ALCL) are B and T cell lymphomas respectively, which express the tumour necrosis factor receptor superfamily member, CD30. Another
Externí odkaz:
https://doaj.org/article/d6fb416cc68a41c285641ca69ded162a
Publikováno v:
Pathogens, Vol 11, Iss 8, p 875 (2022)
Poxviruses are double-stranded DNA viruses that infect insects and a variety of vertebrate species. The large genomes of poxviruses contain numerous genes that allow these viruses to successfully establish infection, including those that help evade t
Externí odkaz:
https://doaj.org/article/29ba5effea294384accecc248d73a8dd
Anaplastic lymphoma kinase-positive, anaplastic large cell lymphoma (ALK+ ALCL) is a T cell lymphoma which features translocations or inversion involving the ALK tyrosine kinase gene, and results in oncogenic fusion proteins (e.g. NPM-ALK). The eleva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b1f3d9da62bc2086dd46d1ceccf35b7
https://doi.org/10.1101/2022.06.10.495605
https://doi.org/10.1101/2022.06.10.495605
Publikováno v:
Virus Research. 323:198968
p28 is a poxvirus-encoded E3 ubiquitin ligase that possesses an N-terminal KilA-N domain and a C-terminal RING domain. In Ectromelia virus (ECTV), disruption of the p28 RING domain severely attenuated virulence in A strain mice, which normally succum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bcf47c073109dc05d9f87dbff2ff2f1
https://doi.org/10.1016/j.virusres.2022.198968
https://doi.org/10.1016/j.virusres.2022.198968
Publikováno v:
Experimental Hematology & Oncology
Experimental Hematology & Oncology, Vol 10, Iss 1, Pp 1-12 (2021)
Experimental Hematology & Oncology, Vol 10, Iss 1, Pp 1-12 (2021)
Classical Hodgkin lymphoma (cHL) and anaplastic lymphoma kinase-positive, anaplastic large cell lymphoma (ALK+ ALCL) are B and T cell lymphomas respectively, which express the tumour necrosis factor receptor superfamily member, CD30. Another feature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655c4b92f32ca1bd9ab040c1c5c584f3
https://pubmed.ncbi.nlm.nih.gov/33413671
https://pubmed.ncbi.nlm.nih.gov/33413671
Autor:
Julinor T. C. Bacani, Zuoqiao Wu, Eugeniu Jantuan, Ying-Han R. Hsu, Anton Savin, Mihye Yang, Robert J. Ingham, Jingxi Zhang
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Classical Hodgkin Lymphoma (cHL) is primarily a B cell lymphoid neoplasm and a member of the CD30–positive lymphomas. cHL and the other CD30–positive lymphomas are characterized by the elevated expression and/or constitutive activation of the act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2849c347bc5d26f901b3095859ff36d1
http://europepmc.org/articles/PMC6207696
http://europepmc.org/articles/PMC6207696
Autor:
Hyun-Suk Lim, Jacob J. Adler, Ross Cocklin, Misook Oh, Mark G. Goebl, William P. Ranahan, Brigitte L. Heller, Lauren R. Bringman, Clark D. Wells, Robert J. Ingham
Publikováno v:
Journal of Biological Chemistry. 288:15181-15193
The adaptor protein Amot130 scaffolds components of the Hippo pathway to promote the inhibition of cell growth. This study describes how Amot130 through binding and activating the ubiquitin ligase AIP4/Itch achieves these effects. AIP4 is found to bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51a8dc5d3dc5ec9d0e50ff916e75d322
https://doi.org/10.1074/jbc.m112.446534
https://doi.org/10.1074/jbc.m112.446534
Autor:
Esther Ekpe Adewuyi, Pascale Gelebart, David Williams, Todd P. W. McMullen, Robert J. Ingham, Mark A. Dykstra, Peng Wang, Raymond Lai, Jingdong Zhang
Publikováno v:
The Journal of Pathology. 228:241-250
Lymph node metastases are common in papillary thyroid cancer (PTC) and can be resistant to surgical extirpation or radioiodine ablation. We examined the role of platelet-derived growth factor receptor (PDGFR) in mediating lymph node metastases in PTC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81ce9423139f3d534295ff735c069b6e
https://doi.org/10.1002/path.4069
https://doi.org/10.1002/path.4069
Autor:
Raymond Lai, Jingdong Zhang, Liang Li, Todd P. W. McMullen, Robert J. Ingham, Peng Wang, Leah C. Young, Fang Wu
Publikováno v:
Carcinogenesis. 32:146-153
It is well established that the tumorigenic potential of nucleophosmin (NPM)―anaplastic lymphoma kinase (ALK), an oncogenic tyrosine kinase, is dependent on its tyrosine phosphorylation. Using tandem affinity purification―mass spectrometry, we fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a91d294b9175be4fc06052d207adcd
https://doi.org/10.1093/carcin/bgq229
https://doi.org/10.1093/carcin/bgq229
Publikováno v:
Oncogene. 23:1972-1984
Neuronal precursor cell-expressed developmentally downregulated 4 (Nedd4) is the prototypical protein in a family of E3 ubiquitin ligases that have a common domain architecture. They are comprised of a catalytic C-terminal HECT domain and N-terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1a6025447df050cf11d65da9775ef9
https://doi.org/10.1038/sj.onc.1207436
https://doi.org/10.1038/sj.onc.1207436