Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Robert J. Heuermann"'
Autor:
Khairunisa Mohamad Ibrahim, Nicolas Massaly, Hye-Jean Yoon, Rossana Sandoval, Allie J. Widman, Robert J. Heuermann, Sidney Williams, William Post, Sulan Pathiranage, Tania Lintz, Azra Zec, Ashley Park, Waylin Yu, Thomas L. Kash, Robert W. Gereau, Jose A. Morón
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The hippocampus is pivotal in integrating emotional processing, learning, memory, and reward-related behaviors. The dorsal hippocampus (dHPC) is particularly crucial for episodic, spatial, and associative memory, and has been shown to be nec
Externí odkaz:
https://doaj.org/article/87fdb1df68f64020b4bcdb032e7d7959
Characterization of hyperpolarization-activated cyclic nucleotide-gated channels in oligodendrocytes
Autor:
Kyle A. Lyman, Ye Han, Andrew P. Robinson, Samuel E. Weinberg, Daniel W. Fisher, Robert J. Heuermann, Reagan E. Lyman, Dong Kyu Kim, Andreas Ludwig, Navdeep S. Chandel, Mark D. Does, Stephen D. Miller, Dane M. Chetkovich
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Mature oligodendrocytes (OLG) are the myelin-forming cells of the central nervous system. Recent work has shown a dynamic role for these cells in the plasticity of neural circuits, leading to a renewed interest in voltage-sensitive currents in OLG. H
Externí odkaz:
https://doaj.org/article/c67dec0a15aa414d882f60a7225696ea
Autor:
Robert J. Heuermann, Thomas C. Jaramillo, Shui-Wang Ying, Benjamin A. Suter, Kyle A. Lyman, Ye Han, Alan S. Lewis, Thomas G. Hampton, Gordon M.G. Shepherd, Peter A. Goldstein, Dane M. Chetkovich
Publikováno v:
Neurobiology of Disease, Vol 85, Iss , Pp 81-92 (2016)
Absence seizures occur in several types of human epilepsy and result from widespread, synchronous feedback between the cortex and thalamus that produces brief episodes of loss of consciousness. Genetic rodent models have been invaluable for investiga
Externí odkaz:
https://doaj.org/article/4a42cc8196d449e28a6fc1fc270660d3
Autor:
Daniel A. Nicholson, Kyle A. Lyman, Hongxin Dong, Daniel W. Fisher, Robert J. Heuermann, Ye Han, Kendall M. Foote, Natividad Ybarra, Linda A. Bean, Dane M. Chetkovich
Publikováno v:
Journal of Neurochemistry. 146:753-766
Active coping is an adaptive stress response that improves outcomes in medical and neuropsychiatric diseases. To date, most research into coping style has focused on neurotransmitter activity and little is known about the intrinsic excitability of ne
Autor:
Mehrnoush Zobeiri, Maia Datunashvili, Sabine Balfanz, Gilles van Luijtelaar, Hans-Christian Pape, Arnd Baumann, Rahul Chaudhary, Venu Narayanan, Annika Lüttjohann, Dane M. Chetkovich, Robert J. Heuermann, Patrick Meuth, Thomas Budde
Publikováno v:
Brain Structure & Function
Brain Structure and Function, 223, 1537-1564
Brain structure & function 223, 1537-1564 (2018). doi:10.1007/s00429-017-1559-z
Brain Structure and Function, 223, 3, pp. 1537-1564
Brain Structure and Function, 223, 1537-1564
Brain structure & function 223, 1537-1564 (2018). doi:10.1007/s00429-017-1559-z
Brain Structure and Function, 223, 3, pp. 1537-1564
Hyperpolarization-activated cyclic nucleotide-gated cation (HCN) channels have important functions in controlling neuronal excitability and generating rhythmic oscillatory activity. The role of tetratricopeptide repeat-containing Rab8b-interacting pr
Autor:
Dane M. Chetkovich, Geoffrey T. Swanson, James S. Trimmer, Kyle A. Lyman, Ioannis E. Michailidis, Kendall M. Foote, Robert J. Heuermann, Danielle Mandikian, Ye Han
Publikováno v:
J Biol Chem
Temporal lobe epilepsy (TLE) is a prevalent neurological disorder with many patients experiencing poor seizure control with existing anti-epileptic drugs. Thus, novel insights into the mechanisms of epileptogenesis and identification of new drug targ
Autor:
Kyle A. Lyman, Robert J. Heuermann, Dane M. Chetkovich, Daniel W. Fisher, Quratul Ain Ismail, Ye Han
Publikováno v:
Molecular psychiatry
Major depressive disorder (MDD) is a prevalent psychiatric condition with limited therapeutic options beyond monoaminergic therapies. Although effective in some individuals, many patients fail to respond adequately to existing treatments, and new pha
Autor:
Paul P. Van Veldhoven, Robert J. Heuermann, Reagan E. Lyman, Ye Han, Kyle A. Lyman, Xiangying Cheng, Dane M. Chetkovich, Jonathan E. Kurz
Tetratricopeptide repeat (TPR) domains are ubiquitous structural motifs that mediate protein-protein interactions. For example, the TPR domains in the peroxisomal import receptor PEX5 enable binding to a range of type 1 peroxisomal targeting signal (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77dcb7662dc011ec0490ad91c10ebb23
https://lirias.kuleuven.be/handle/123456789/595945
https://lirias.kuleuven.be/handle/123456789/595945
Autor:
Mark E. J. Sheffield, Gabrielle B. Edgerton, Robert J. Heuermann, Brett D. Mensh, Tara Deemyad, Nelson Spruston
Publikováno v:
The Journal of Physiology. 591:4793-4805
Key points • Persistent firing can be triggered in a population of inhibitory interneurons found in the hippocampus and neocortex. Repeated stimulation eventually triggers an autonomous barrage of spikes that is generated and maintained in the axon