Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Robert J. H. Austin"'
Autor:
Deborah Needham, Jason A. Holt, Stuart N. Farrow, Robert J. H. Austin, Keith Biggadike, Karen Leavens, Iain Uings, Davina C. Angell, Michael V. Haase, Joyce Lesley Matthews
Publikováno v:
British Journal of Pharmacology. 169:1389-1403
Background and Purpose Glucocorticoids are highly effective therapies for a range of inflammatory diseases. Advances in the understanding of the diverse molecular mechanisms underpinning glucocorticoid action suggest that anti-inflammatory molecules
Autor:
Robert J. H. Austin, Christopher Patten, Eugene L. Stewart, Simon Taylor, Peter Brown, Christopher M. Yates, Davina C. Angell, Jason A. Holt, Rosemary Z. Sasse, Iain Uings, Ryan P. Trump, Jodi M. Maglich
Publikováno v:
Journal of Medicinal Chemistry. 53:4531-4544
Glucocorticoid receptor (GR) agonists have been used for more than half a century as the most effective treatment of acute and chronic inflammatory conditions despite serious side effects that accompany their extended use that include glucose intoler
Autor:
Shawn P. Williams, Eugene L. Stewart, Iain M. McLay, Robert J. H. Austin, Steven A. Short, Ian J. Uings, John B. Pritchard, Millard H. Lambert, Kevin P. Madauss, Su-Jun Deng
Publikováno v:
Journal of Medicinal Chemistry. 47:3381-3387
Although progesterone, the natural ligand of the progesterone receptor (PR), has a hydrogen atom at the 17alpha position, other potent steroid agonists such as norethindrone and mometasone furoate have larger substituents at this position that are ac
Autor:
Eric L. Eisenstein, Edwin M. Noga, Gilbert Gleim, Robert J. H. Austin, Truls Østbye, Galen S. Wagner, Kathryn M. Andolsek, Margaret Gradison, James C. Leist, Thomas H. Davis, Anne Courtney-Eighmy, Håkan Arheden, Charles Maynard
Publikováno v:
Journal of electrocardiology. 39(1)
Purpose: To determine whether a short-term, problem-based educational intervention leads to increased research activity among health care practitioners. Subjects and Methods: Participant's success was evaluated as a composite of 2 outcomes. These wer
Autor:
E. Meldrum, A. Walker, Robert J. H. Austin, Iain Uings, B. Maschera, L. Fairbairn, Stuart N. Farrow
Publikováno v:
The European respiratory journal. 20(6)
Fluticasone propionate (FP) and mometasone furoate (MF) are potent synthetic corticosteroids that are widely used as anti-inflammatory agents to treat respiratory diseases. As part of the assessment of the potential for side-effects associated with t