Zobrazeno 1 - 10
of 1 461
pro vyhledávání: '"Robert J. Glynn"'
Autor:
Katherine P. Liao, Pamela Rist, Jon Giles, Leah Santacroce, Margery A. Connelly, Robert J. Glynn, Paul Ridker, Ahmed Tawakol, Joan Bathon, Daniel H. Solomon
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-9 (2024)
Abstract Background Treatments for rheumatoid arthritis (RA) are associated with complex changes in lipids and lipoproteins that may impact cardiovascular (CV) risk. The objective of this study was to examine lipid and lipoprotein changes associated
Externí odkaz:
https://doaj.org/article/1c5c699bc81445dabdab7e0cb72982ed
Autor:
Darae Ko, Peter T. Evans, Kueiyu Joshua Lin, Ashvin N. Pande, Alexander Cervone, Su Been Lee, Susan Cheng, Theodore Tsacogianis, Robert J. Glynn, Dae Hyun Kim
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 15 (2024)
Background Ticagrelor is recommended over clopidogrel in acute coronary syndrome based on the results of the PLATO (Study of Platelet Inhibition and Patient Outcomes) trial. We aimed to emulate PLATO in older adults with and without frailty and with
Externí odkaz:
https://doaj.org/article/566180384cb643828b21308205d89c7b
Autor:
Phyo T. Htoo, Helen Tesfaye, Sebastian Schneeweiss, Deborah J. Wexler, Brendan M. Everett, Robert J. Glynn, Niklas Schmedt, Lisette Koeneman, Anouk Déruaz-Luyet, Julie M. Paik, Elisabetta Patorno
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background No randomized clinical trials have directly compared the cardiorenal effectiveness of empagliflozin and GLP-1RA agents with demonstrated cardioprotective effects in patients with a broad spectrum of cardiovascular risk. We reporte
Externí odkaz:
https://doaj.org/article/a409dae7b8d64bffbc67fb3a8cee406b
Autor:
Phyo T. Htoo, Helen Tesfaye, Sebastian Schneeweiss, Deborah J. Wexler, Brendan M. Everett, Robert J. Glynn, Niklas Schmedt, Lisette Koeneman, Anouk Déruaz-Luyet, Julie M. Paik, Elisabetta Patorno
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/1b45064e466d4e25abc84ea3e931b788
Autor:
Daniel H Solomon, Robert J Glynn, Niteesh K Choudhry, Julie C Lauffenburger, Elliott M Antman, Su Been Lee, Helen Tesfaye, Angela Tong
Publikováno v:
BMJ Open, Vol 13, Iss 11 (2023)
Objective Poor medication adherence remains highly prevalent and adversely affects health outcomes. Patients frequently describe properties of the pills themselves, like size and shape, as barriers, but this has not been evaluated objectively. We sou
Externí odkaz:
https://doaj.org/article/ea3708e7ec0d49e3ab4121ede648a5bc
Publikováno v:
Stats, Vol 6, Iss 2, Pp 526-538 (2023)
The area under the true ROC curve (AUC) is routinely used to determine how strongly a given model discriminates between the levels of a binary outcome. Standard inference with the AUC requires that outcomes be independent of each other. To overcome t
Externí odkaz:
https://doaj.org/article/7338caba236443578d45b77b8db4e646
Autor:
Jon T. Giles, Pamela M. Rist, Katherine P. Liao, Ahmed Tawakol, Zahi A. Fayad, Venkatesh Mani, Nina P. Paynter, Paul M. Ridker, Robert J. Glynn, Fengxin Lu, Rachel Broderick, Meredith Murray, Kathleen M. M. Vanni, Daniel H. Solomon, Joan M. Bathon
Publikováno v:
ACR Open Rheumatology, Vol 3, Iss 6, Pp 371-380 (2021)
Individuals with rheumatoid arthritis (RA) are at increased risk for atherosclerotic cardiovascular disease (ASCVD) events relative to the general population, potentially mediated by atherosclerotic plaques that are more inflamed and rupture prone. W
Externí odkaz:
https://doaj.org/article/e842df4b45cc4bd49735e4e8887b967e
Autor:
Julie C. Lauffenburger, Thomas Isaac, Lorenzo Trippa, Punam Keller, Ted Robertson, Robert J. Glynn, Thomas D. Sequist, Dae H. Kim, Constance P. Fontanet, Edward W. B. Castonguay, Nancy Haff, Renee A. Barlev, Mufaddal Mahesri, Chandrashekar Gopalakrishnan, Niteesh K. Choudhry
Publikováno v:
Implementation Science, Vol 16, Iss 1, Pp 1-11 (2021)
Abstract Background The prescribing of high-risk medications to older adults remains extremely common and results in potentially avoidable health consequences. Efforts to reduce prescribing have had limited success, in part because they have been sub
Externí odkaz:
https://doaj.org/article/7b128188241647069341e3d6259f1acf
Autor:
Kathleen M.M. Vanni, Nancy Berliner, Nina P. Paynter, Robert J. Glynn, Jean MacFadyen, Joshua Colls, Fengxin Lu, Chang Xu, Paul M. Ridker, Daniel H. Solomon
Publikováno v:
ACR Open Rheumatology, Vol 2, Iss 12, Pp 697-704 (2020)
Objective Low‐dose methotrexate (LD‐MTX), a cornerstone in the treatment of rheumatoid arthritis, is associated with a moderately increased risk of anemia, leukopenia, and skin cancers, but the risks of myelosuppression and malignancy during LD
Externí odkaz:
https://doaj.org/article/d93c1b69b42b46fcb1dcf9a1ecfb8152
Autor:
David Mengel, Wen Liu, Robert J. Glynn, Dennis J. Selkoe, Andre Strydom, Florence Lai, H. Diana Rosas, Amy Torres, Vasiliki Patsiogiannis, Brian Skotko, Dominic M. Walsh
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2020)
Abstract Background Down syndrome (DS) is the most common genetic cause of Alzheimer’s disease (AD), but diagnosis of AD in DS is challenging due to the intellectual disability which accompanies DS. When disease-modifying agents for AD are approved
Externí odkaz:
https://doaj.org/article/765d7c94e9064dc89f729ff61c72457b