Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Robert J. Fleischaker"'
Autor:
Donald J. Giard, William G. Thilly, Toshiko Imamura, Robert J. Fleischaker, Henri Brunengraber, Charles L. Crespi, Phaik Mooi Leong
Publikováno v:
Biotechnology and Bioengineering. 23:2673-2689
This report reviews recent progress in micro carrier technology at the Massachusetts Institute of Technology. This progress includes new understanding of the nutritional needs of high-cell density micro carrier cultures, the demonstration of cell gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::577938649f2c8445f5b383db7eef7727
https://doi.org/10.1002/bit.260231204
https://doi.org/10.1002/bit.260231204
Publikováno v:
Annals of the New York Academy of Sciences. 413:355-372
Mammalian cell products have great medical and clinical importance, but to date, production methods employed to manufacture these products on a large scale are not as cost efficient as they could be. The implementation of process control would greatl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81fa5edeab08da09e290d12420c5f647
https://doi.org/10.1111/j.1749-6632.1983.tb47912.x
https://doi.org/10.1111/j.1749-6632.1983.tb47912.x
Publikováno v:
Annals of the New York Academy of Sciences. 369:47-59
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c2600765b4db1d94e3b110bcfdd639
https://doi.org/10.1111/j.1749-6632.1981.tb14176.x
https://doi.org/10.1111/j.1749-6632.1981.tb14176.x
Publikováno v:
Trends in Biotechnology. 1:102-108
If biological products such as monoclonal antibodies, interferons, vaccines, plasminogen activators and many others are to be obtained at an economic cost from mammalian cells, a number of engineering problems must be solved (Tables 1 and 2). The two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50ad44545ed34bf7d961de7de6d09490
https://doi.org/10.1016/0167-7799(83)90032-x
https://doi.org/10.1016/0167-7799(83)90032-x
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 42:772-776
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d424d856f992018a5c609099c08b45b
https://doi.org/10.1016/s0022-5223(19)32545-0
https://doi.org/10.1016/s0022-5223(19)32545-0
Autor:
Harry S. Pollard, Joseph J. Timmes, Karl E. Karlson, Betty L. Vestal, Robert J. Fleischaker, Marvin L. Gliedman, Robert D. Sellers
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 44:189-203
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d03db2e673b39b3316a36c087e598950
https://doi.org/10.1016/s0022-5223(19)32972-1
https://doi.org/10.1016/s0022-5223(19)32972-1
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 47:289-297
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::108b32c3aecdfc3218845a7b5d05d77c
https://doi.org/10.1016/s0022-5223(20)31503-8
https://doi.org/10.1016/s0022-5223(20)31503-8
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 170(2)
The effect of temperature upon interferon production in human fibroblasts was examined. Kinetic studies showed that exposing the cells to 37° for one hour before lowering the temperature to 30° resulted in a more prolonged period of production in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f537b10c7eff8b84c858fdb3c7867c7e
https://pubmed.ncbi.nlm.nih.gov/6178114
https://pubmed.ncbi.nlm.nih.gov/6178114
Publikováno v:
Biotechnology and bioengineering. 28(9)
Mammalian cells grown in culture excrete lactic acid and ammonium ions in quantities that may limit growth and reduce product synthesis. Frequent replenishment of the culture medium is often necessary to prevent waste product accumulation which could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b7054cb21f0181d0cbe2080d264e73
https://pubmed.ncbi.nlm.nih.gov/18561227
https://pubmed.ncbi.nlm.nih.gov/18561227
Although instrumentation for work with microbial cells is highly developed, the use of instrumentation for animal cell culture leaves much to be desired. This lack of progress was mainly due to the surface requirement of normal diploid cells. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3053bba0df3ef0ca99ceb755d37f112
https://doi.org/10.1016/b978-0-08-025383-1.50075-8
https://doi.org/10.1016/b978-0-08-025383-1.50075-8
