Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Robert J. Fern"'
A role for T-type Ca2+channels in the synergistic control of aldosterone production by ANG II and K+
Publikováno v:
American Journal of Physiology-Renal Physiology. 276:F674-F683
Independently, plasma K+and ANG II stimulate aldosterone secretion from adrenal glomerulosa (AG) cells, but together they synergistically control production. We studied mechanisms to mediate this synergy using bovine AG cells studied under physiologi
Publikováno v:
American Journal of Physiology-Renal Physiology. 269:F751-F760
We recently reported that elevations in the intracellular Ca2+ concentration ([Ca2+]i) enhance low-voltage-activated, T-type, Ca2+ channel activity via Ca2+/calmodulin-dependent protein kinase II (CaMKII). Here, we document CaMKII activity in bovine
Publikováno v:
American Journal of Physiology-Renal Physiology. 267:F183-F189
The T-type Ca2+ channel is unique among voltage-dependent Ca2+ channels in its low threshold for opening and its slow kinetics of deactivation. Here, we evaluate the importance of intracellular Ca2+ (Cai2+) in promoting low-threshold gating of T-type
Publikováno v:
The American journal of physiology. 262(3 Pt 2)
To determine the ontogeny of intrarenal distribution of guanosine 3',5'-cyclic monophosphate (cGMP) formation in response to atrial natriuretic peptide (ANP) or sodium nitroprusside (SNP), adult and neonatal Sprague-Dawley rats were anesthetized and
Autor:
Robert J. Fern, Christine M. Yesko, Oliver Smithies, Barbara A. Thornhill, Robert L. Chevalier, Hyung-Suk Kim
Publikováno v:
Pediatric Research. 43:306-306
The renin-angiotensin system (RAS) may serve pathogenic as well as salutary roles in the development of renal disease, and angiotensin II has been implicated to regulate cellular mechanisms of fibrosis. To advance the understanding of the contributio