Gene Therapy for Fibrodysplasia Ossificans Progressiva

Autor: Elisabeth M.W. Eekhoff, Ruben D. de Ruiter, Bernard J. Smilde, Ton Schoenmaker, Teun J. de Vries, Coen Netelenbos, Edward C. Hsiao, Christiaan Scott, Nobuhiko Haga, Zvi Grunwald, Carmen L. De Cunto, Maja di Rocco, Patricia L. R. Delai, Robert J. Diecidue, Vrisha Madhuri, Tae-Joon Cho, Rolf Morhart, Clive S. Friedman, Michael Zasloff, Gerard Pals, Jae-Hyuck Shim, Guangping Gao, Frederick Kaplan, Robert J. Pignolo, Dimitra Micha

Publikováno v: Eekhoff, E M W, de Ruiter, R D, Smilde, B J, Schoenmaker, T, de Vries, T J, Netelenbos, C, Hsiao, E C, Scott, C, Haga, N, Grunwald, Z, De Cunto, C L, di Rocco, M, Delai, P L R, Diecidue, R J, Madhuri, V, Cho, T J, Morhart, R, Friedman, C S, Zasloff, M, Pals, G, Shim, J H, Gao, G, Kaplan, F, Pignolo, R J & Micha, D 2022, ' Gene Therapy for Fibrodysplasia Ossificans Progressiva : Feasibility and Obstacles ', Human gene therapy, vol. 33, no. 15-16, pp. 782-788 . https://doi.org/10.1089/hum.2022.023
Eekhoff, E M W, de Ruiter, R D, Smilde, B J, Schoenmaker, T, de Vries, T J, Netelenbos, C, Hsiao, E C, Scott, C, Haga, N, Grunwald, Z, de Cunto, C L, di Rocco, M, Delai, P L R, Diecidue, R J, Madhuri, V, Cho, T-J, Morhart, R, Friedman, C S, Zasloff, M, Pals, G, Shim, J-H, Gao, G, Kaplan, F, Pignolo, R J & Micha, D 2022, ' Gene Therapy for Fibrodysplasia Ossificans Progressiva : Feasibility and Obstacles ', Human Gene Therapy, vol. 33, no. 15-16, pp. 782-788 . https://doi.org/10.1089/hum.2022.023, https://doi.org/10.1089/hum.2022.023

Fibrodysplasia ossificans progressiva (FOP) is a rare and devastating genetic disease, in which soft connective tissue is converted into heterotopic bone through an endochondral ossification process. Patients succumb early as they gradually become tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f624caf1588f9bd3b3300ebfe4d9333d
https://doi.org/10.1089/hum.2022.023

Myoepithelial carcinoma of the palate: a case report of a rare lesion

Autor: Timothy M. Adams, Allen F. Champion, Robert J. Diecidue, Lionel Gold

Publikováno v: European Journal of Oral and Maxillofacial Surgery. 4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::241cec6bd3dc016c7fd3d07fdaa24a5c
https://doi.org/10.23736/s2532-3466.20.00205-2

Special considerations for clinical trials in fibrodysplasia ossificans progressiva (FOP)

Autor: Robert J. Diecidue, Edward C. Hsiao, Clive S. Friedman, Keqin Zhang, Elisabeth M.W. Eekhoff, Tae Joon Cho, Mona Al Mukaddam, Richard Keen, Zvi Grunwald, Maja Di Rocco, Coen Netelenbos, Matthew A. Brown, Amanda Cali, F.S. Kaplan, Patricia Delai, Geneviève Baujat, Michael Zasloff, Carmen De Cunto, Robert J. Pignolo, Rolf Morhart, Nobuhiko Haga, Christiaan Scott

Publikováno v: British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology, 85(6), 1199-1207. Wiley-Blackwell
British journal of clinical pharmacology, vol 85, iss 6
Hsiao, E C, di Rocco, M, Cali, A, Zasloff, M, Al Mukaddam, M, Pignolo, R J, Grunwald, Z, Netelenbos, C, Keen, R, Baujat, G, Brown, M A, Cho, T-J, de Cunto, C, Delai, P, Haga, N, Morhart, R, Scott, C, Zhang, K, Diecidue, R J, Friedman, C S, Kaplan, F S & Eekhoff, E M W 2019, ' Special considerations for clinical trials in fibrodysplasia ossificans progressiva (FOP) ', British Journal of Clinical Pharmacology, vol. 85, no. 6, pp. 1199-1207 . https://doi.org/10.1111/bcp.13777

Clinical trials for orphan diseases are critical for developing effective therapies. One such condition, fibrodysplasia ossificans progressiva (FOP; MIM#135100), is characterized by progressive heterotopic ossification (HO) that leads to severe disab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc218e94e369f2cb1586171ce111dee
http://europepmc.org/articles/PMC6533500

Population-Based Trends in Outcomes in Mucoepidermoid Carcinoma of the Oral Cavity

Autor: A.D. Congiusta, Robert J. Diecidue, C. Connors, A. Yampolsky

Publikováno v: Journal of Oral and Maxillofacial Surgery. 77:e82-e83

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d56e303e4dba8e649f623531b6f5dcc8
https://doi.org/10.1016/j.joms.2019.06.110

Are Solid Organ Transplant Patients the New Unsuspecting Osteonecrosis Victims?

Autor: Robert J. Diecidue, Shachika Khanna, Alyssa Flashburg

Publikováno v: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 128:e23-e24

Purpose Bone disease is common in organ transplant recipients. Immunosuppressive regimens with glucocorticoids have shown to improve patient and graft survival rates following transplantation. As survival rates have improved, so has awareness of long

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::285c1b528ead70e60ddce8b072814367
https://doi.org/10.1016/j.oooo.2019.02.254