Zobrazeno 1 - 10
of 464
pro vyhledávání: '"Robert J. Capon"'
Autor:
Taizong Wu, Waleed M. Hussein, Kaumadi Samarasekera, Yuxuan Zhu, Zeinab G. Khalil, Shengbin Jin, David F. Bruhn, Yovany Moreno, Angela A. Salim, Robert J. Capon
Publikováno v:
Marine Drugs, Vol 22, Iss 7, p 312 (2024)
A bioassay-guided chemical investigation of a bacterium, Streptomyces sp. CMB-MRB032, isolated from sheep feces collected near Bathurst, Victoria, Australia, yielded the known polyketide antimycins A4a (1) and A2a (2) as potent inhibitors of Dirofila
Externí odkaz:
https://doaj.org/article/7dfee6623d574281aa36f24706d9ac2b
Publikováno v:
Marine Drugs, Vol 22, Iss 6, p 243 (2024)
Subjecting the Australian marine-derived fungus Aspergillus noonimiae CMB-M0339 to cultivation profiling using an innovative miniaturized 24-well plate format (MATRIX) enabled access to new examples of the rare class of 2,6-diketopiperazines, noonazi
Externí odkaz:
https://doaj.org/article/d71ed68479be46919e770be6c4fd96d6
Autor:
Prashamsa Koirala, Ahmed O. Shalash, Sung-Po R. Chen, Mohammad O. Faruck, Jingwen Wang, Waleed M. Hussein, Zeinab G. Khalil, Robert J. Capon, Michael J. Monteiro, Istvan Toth, Mariusz Skwarczynski
Publikováno v:
Vaccines, Vol 12, Iss 2, p 198 (2024)
Mucosal vaccines are highly attractive due to high patient compliance and their suitability for mass immunizations. However, all currently licensed mucosal vaccines are composed of attenuated/inactive whole microbes, which are associated with a varie
Externí odkaz:
https://doaj.org/article/5a9c2bd3c5f744ec9d8faa3409c0b6d3
Publikováno v:
Antibiotics, Vol 13, Iss 1, p 97 (2024)
The Australian roadside soil-derived fungus Penicillium shearii CMB-STF067 was prioritized for chemical investigation based on an SDA cultivation extract exhibiting both antibacterial properties and natural products with unprecedented molecular formu
Externí odkaz:
https://doaj.org/article/04808145175f407782fe73ec494e621b
Autor:
Angela A. Salim, Waleed M. Hussein, Pradeep Dewapriya, Huy N. Hoang, Yahao Zhou, Kaumadi Samarasekera, Zeinab G. Khalil, David P. Fairlie, Robert J. Capon
Publikováno v:
Marine Drugs, Vol 21, Iss 9, p 487 (2023)
Application of a miniaturized 24-well plate system for cultivation profiling (MATRIX) permitted optimization of the cultivation conditions for the marine-derived fungus Talaromyces sp. CMB-TU011, facilitating access to the rare cycloheptapeptide tala
Externí odkaz:
https://doaj.org/article/42f42ea2be534df994531dff6bea61a8
Publikováno v:
Marine Drugs, Vol 21, Iss 7, p 413 (2023)
In reviewing a selection of recent case studies from our laboratory, we revealed some lessons learned and benefits accrued from the application of mass spectrometry (MS/MS) molecular networking in the field of marine sponge natural products. Molecula
Externí odkaz:
https://doaj.org/article/c9ad191cbcec4a50a1866b39264eeba2
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Chemical cues produced by late-stage embryos of the cane toad (Rhinella marina) attract older conspecific larvae, which are highly cannibalistic and can consume an entire clutch. To clarify the molecular basis of this attraction response, we
Externí odkaz:
https://doaj.org/article/8ea7b1abda614b9b8d7ef09680c7d804
Publikováno v:
Microorganisms, Vol 11, Iss 4, p 1005 (2023)
Rosenbergiella bacteria have been previously isolated predominantly from floral nectar and identified in metagenomic screenings as associated with bees. Here, we isolated three Rosenbergiella strains from the robust Australian stingless bee Tetragonu
Externí odkaz:
https://doaj.org/article/69c1bb93817949c3b5b4a478c3101aeb
Autor:
Jieru Yang, Jennifer C. Boer, Mattaka Khongkow, Sarunya Phunpee, Zeinab G. Khalil, Sahra Bashiri, Cyril Deceneux, Georgia Goodchild, Waleed M. Hussein, Robert J. Capon, Uracha Ruktanonchai, Magdalena Plebanski, Istvan Toth, Mariusz Skwarczynski
Publikováno v:
Vaccines, Vol 11, Iss 2, p 305 (2023)
Intranasal vaccine administration can overcome the disadvantages of injectable vaccines and present greater efficiency for mass immunization. However, the development of intranasal vaccines is challenged by poor mucosal immunogenicity of antigens and
Externí odkaz:
https://doaj.org/article/646a8cd56d304937890b73924c2f122e
Publikováno v:
Molecules, Vol 27, Iss 24, p 9066 (2022)
This study showcases the application of an integrated workflow of molecular networking chemical profiling (GNPS), together with miniaturized microbioreactor cultivation profiling (MATRIX) to successfully detect, dereplicate, prioritize, optimize the
Externí odkaz:
https://doaj.org/article/5473d0ebd67c4e9ba977b104c692db6e