Zobrazeno 1 - 10
of 594
pro vyhledávání: '"Robert J. Capon"'
Publikováno v:
Marine Drugs, Vol 22, Iss 10, p 454 (2024)
The first total synthesis of the Australian marine tunicate fungus-derived cyclic peptide talarolide A (1) has confirmed the structure previously proposed on the basis of spectroscopic and chemical analyses and re-affirmed the importance of the uniqu
Externí odkaz:
https://doaj.org/article/a53523056aa941fbb33199c35f78b6b4
Autor:
Shengbin Jin, David F. Bruhn, Cynthia T. Childs, Erica Burkman, Yovany Moreno, Angela A. Salim, Zeinab G. Khalil, Robert J. Capon
Publikováno v:
Antibiotics, Vol 13, Iss 10, p 989 (2024)
An investigation of ×19 soil samples collected under the auspices of the Australian citizen science initiative, Soils for Science, returned ×559 chemically dereplicated microbial isolates, of which ×54 exhibited noteworthy anthelmintic activity ag
Externí odkaz:
https://doaj.org/article/5c700a0e02034bfbbb5aaa87bb972510
Autor:
Taizong Wu, Waleed M. Hussein, Kaumadi Samarasekera, Yuxuan Zhu, Zeinab G. Khalil, Shengbin Jin, David F. Bruhn, Yovany Moreno, Angela A. Salim, Robert J. Capon
Publikováno v:
Marine Drugs, Vol 22, Iss 7, p 312 (2024)
A bioassay-guided chemical investigation of a bacterium, Streptomyces sp. CMB-MRB032, isolated from sheep feces collected near Bathurst, Victoria, Australia, yielded the known polyketide antimycins A4a (1) and A2a (2) as potent inhibitors of Dirofila
Externí odkaz:
https://doaj.org/article/7dfee6623d574281aa36f24706d9ac2b
Publikováno v:
Marine Drugs, Vol 22, Iss 6, p 243 (2024)
Subjecting the Australian marine-derived fungus Aspergillus noonimiae CMB-M0339 to cultivation profiling using an innovative miniaturized 24-well plate format (MATRIX) enabled access to new examples of the rare class of 2,6-diketopiperazines, noonazi
Externí odkaz:
https://doaj.org/article/d71ed68479be46919e770be6c4fd96d6
Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice
Autor:
Jeroen Overman, Frank Fontaine, Mehdi Moustaqil, Deepak Mittal, Emma Sierecki, Natalia Sacilotto, Johannes Zuegg, Avril AB Robertson, Kelly Holmes, Angela A Salim, Sreeman Mamidyala, Mark S Butler, Ashley S Robinson, Emmanuelle Lesieur, Wayne Johnston, Kirill Alexandrov, Brian L Black, Benjamin M Hogan, Sarah De Val, Robert J Capon, Jason S Carroll, Timothy L Bailey, Peter Koopman, Ralf Jauch, Matthew A Cooper, Yann Gambin, Mathias Francois
Publikováno v:
eLife, Vol 12 (2023)
Externí odkaz:
https://doaj.org/article/631c7b6dffdc4c4b823c7ff82a631d2f
Autor:
Prashamsa Koirala, Ahmed O. Shalash, Sung-Po R. Chen, Mohammad O. Faruck, Jingwen Wang, Waleed M. Hussein, Zeinab G. Khalil, Robert J. Capon, Michael J. Monteiro, Istvan Toth, Mariusz Skwarczynski
Publikováno v:
Vaccines, Vol 12, Iss 2, p 198 (2024)
Mucosal vaccines are highly attractive due to high patient compliance and their suitability for mass immunizations. However, all currently licensed mucosal vaccines are composed of attenuated/inactive whole microbes, which are associated with a varie
Externí odkaz:
https://doaj.org/article/5a9c2bd3c5f744ec9d8faa3409c0b6d3
Publikováno v:
Antibiotics, Vol 13, Iss 1, p 97 (2024)
The Australian roadside soil-derived fungus Penicillium shearii CMB-STF067 was prioritized for chemical investigation based on an SDA cultivation extract exhibiting both antibacterial properties and natural products with unprecedented molecular formu
Externí odkaz:
https://doaj.org/article/04808145175f407782fe73ec494e621b
Autor:
Angela A. Salim, Waleed M. Hussein, Pradeep Dewapriya, Huy N. Hoang, Yahao Zhou, Kaumadi Samarasekera, Zeinab G. Khalil, David P. Fairlie, Robert J. Capon
Publikováno v:
Marine Drugs, Vol 21, Iss 9, p 487 (2023)
Application of a miniaturized 24-well plate system for cultivation profiling (MATRIX) permitted optimization of the cultivation conditions for the marine-derived fungus Talaromyces sp. CMB-TU011, facilitating access to the rare cycloheptapeptide tala
Externí odkaz:
https://doaj.org/article/42f42ea2be534df994531dff6bea61a8
Publikováno v:
Marine Drugs, Vol 21, Iss 7, p 413 (2023)
In reviewing a selection of recent case studies from our laboratory, we revealed some lessons learned and benefits accrued from the application of mass spectrometry (MS/MS) molecular networking in the field of marine sponge natural products. Molecula
Externí odkaz:
https://doaj.org/article/c9ad191cbcec4a50a1866b39264eeba2
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Chemical cues produced by late-stage embryos of the cane toad (Rhinella marina) attract older conspecific larvae, which are highly cannibalistic and can consume an entire clutch. To clarify the molecular basis of this attraction response, we
Externí odkaz:
https://doaj.org/article/8ea7b1abda614b9b8d7ef09680c7d804