Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Robert J. Cabelli"'
Changing Patterns of Expression and Subcellular Localization of TrkB in the Developing Visual System
Autor:
Andrew A. Welcher, Karen L. Allendoerfer, Monte J. Radeke, Robert J. Cabelli, Stuart C. Feinstein, Carla J. Shatz
Publikováno v:
The Journal of Neuroscience. 16:7965-7980
Neurotrophins play important roles in the survival, differentiation, and maintenance of CNS neurons. To begin to investigate specific roles for these factors in the mammalian visual system, we have examined the cellular localization of the neurotroph
Publikováno v:
Science. 267:1662-1666
During the development of the visual system of higher mammals, axons from the lateral geniculate nucleus (LGN) become segregated into eye-specific patches (the ocular dominance columns) within their target, layer 4 of the primary visual cortex. This
Publikováno v:
The Journal of Neuroscience. 14:1795-1811
Cell division, cell death, and remodeling of connections are major features of the construction of the mammalian CNS. We have begun to address the role of neurotrophins in these events through characterization of the expression of their receptors in
Publikováno v:
Journal of Biological Chemistry. 266:24420-24427
The subcellular localization of SecA, a protein essential for the catalysis of general protein export, was studied to better understand its state(s) and function(s) within Escherichia coli cells. In a wild-type strain approximately half of the cellul
Publikováno v:
Neuron. 19(1)
We have examined the hypothesis that the segregation of LGN axon terminals into ocular dominance (OD) patches in layer 4 of the visual cortex requires neurotrophins, acting as signals to modulate the pattern of synaptic connectivity. Neurotrophin rec
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 87(21)
Escherichia coli azi mutants, whose growth is resistant to millimolar concentrations of sodium azide, were among the earliest E. coli mutants isolated. Genetic complementation, mapping, and DNA sequence analysis now show that these mutations are alle
Publikováno v:
Journal of bioenergetics and biomembranes. 22(3)
Several classes of secA mutants have been isolated which reveal the essential role of this gene product for E. coli cell envelope protein secretion. SecA-dependent, in vitro protein translocation systems have been utilized to show that SecA is an ess
Publikováno v:
Cell. 55:683-692
The soluble and membrane components of an E. coli in vitro protein translocation system prepared from a secA amber mutant, secA13[Am], contain reduced levels of SecA and are markedly defective in both the cotranslational and posttranslational translo
Publikováno v:
Proceedings of the National Academy of Sciences. 85:8953-8957
Genetic analysis of protein secretion in Escherichia coli has identified secY/prlA and secA as components of the secretory apparatus. We have examined the roles of the secY(prlA) gene product (an integral membrane protein) and the soluble secA gene p
Autor:
Craig C. Malbon, Robert J. Cabelli
Publikováno v:
Biochimica et biophysica acta. 544(1)
Cooperative site-to-site interactions among beta-adrenergic receptors of fat cell membranes are probed with the potent beta-adrenergic antagonist (−)-[ 3 H]-dihydroalprenolol according to the kinetic method of De Meyts et al. (De Meyts, P., Roth, J