Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Robert J. Hamm"'
Publikováno v:
Journal of Neurotrauma. 28:1185-1198
Traumatic axonal injury (TAI) is a major feature of traumatic brain injury (TBI) and is associated with much of its morbidity. To date, significant insight has been gained into the initiating pathogenesis of TAI. However, the nature of TAI within the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7df636fbda0acb5c6b14ebf0d9baf64
https://doi.org/10.1089/neu.2011.1756
https://doi.org/10.1089/neu.2011.1756
Autor:
Dong Sun, Zhengwen Zhou, Melissa J. McGinn, Raymond J. Colello, M. Ross Bullock, Nabil Altememi, Sarah Hagood, Robert J. Hamm, Andrew Rolfe
Publikováno v:
Journal of Neurotrauma. 27:923-938
Epidermal growth factor (EGF) is a known mitogen for neural stem and progenitor cells (NS/NPCs) in the central nervous system (CNS). In vitro, EGF maintains NS/NPCs in the proliferative state, whereas in the normal rodent brain it promotes their prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e686589b9ced5f30657fb41cbba02a
https://doi.org/10.1089/neu.2009.1209
https://doi.org/10.1089/neu.2009.1209
Publikováno v:
Journal of Neurotrauma. 26:527-537
Traumatic brain injury (TBI) has been demonstrated to induce cerebral vascular dysfunction that is reflected in altered responses to various vasodilators. While previous reports have focused primarily on the short-term vascular alterations, few have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba7aa0a5e7d5898cf292246afe05a05
https://doi.org/10.1089/neu.2008.0797
https://doi.org/10.1089/neu.2008.0797
Autor:
Dong Sun, Melissa J. McGinn, Robert J. Hamm, M. Ross Bullock, Zhengwen Zhou, Raymond J. Colello, Nabil Altememi, Sarah Hagood
Publikováno v:
Experimental Neurology. 216:56-65
Stem/progenitor cells reside throughout the adult CNS and are actively dividing in the subventricular zone (SVZ) and the dentate gyrus (DG) of the hippocampus. This neurogenic capacity of the SVZ and DG is enhanced following traumatic brain injury (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708c7ab6966aae3dec2f03152f83e17d
https://doi.org/10.1016/j.expneurol.2008.11.011
https://doi.org/10.1016/j.expneurol.2008.11.011
Autor:
David A. Sun, Sompong Sombati, Anya Baranova, Elisa Attkisson, Robert J. Hamm, Laxmikant S. Deshpande, Margaret S. Wilson, Robert J. DeLorenzo
Publikováno v:
Neuroscience Letters. 441:115-119
Traumatic brain injury (TBI) survivors often suffer from a post-traumatic syndrome with deficits in learning and memory. Calcium (Ca(2+)) has been implicated in the pathophysiology of TBI-induced neuronal death. However, the role of long-term changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d30c55585247f7959f28d4884d929e
https://doi.org/10.1016/j.neulet.2008.05.113
https://doi.org/10.1016/j.neulet.2008.05.113
Autor:
Mark D. Whiting, Robert J. Hamm
Publikováno v:
Brain Research. 1213:69-77
Memory impairment is common following traumatic brain injury. However, the specific processes underlying the impairments remain unknown. Traumatic brain injury may interfere with several of the stages of the learning and memory process. In two separa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02bb31e74620548d05179baffee10bb9
https://doi.org/10.1016/j.brainres.2008.01.107
https://doi.org/10.1016/j.brainres.2008.01.107
Publikováno v:
Neuroscience Letters. 436:27-30
Experimental traumatic brain injury (TBI) results in marked neurochemical and metabolic changes. Research has demonstrated that after the initial insult the brain undergoes an immediate state of hypermetabolism followed by a sustained period of hypom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c05745eb9f15f216882e807902512a8
https://doi.org/10.1016/j.neulet.2008.02.046
https://doi.org/10.1016/j.neulet.2008.02.046
Autor:
Robert J. Hamm, Margaret S. Wilson, Laxmikant S. Deshpande, David A. Sun, Anya Baranova, Sompong Sombati, Robert J. DeLorenzo
Publikováno v:
European Journal of Neuroscience. 27:1659-1672
Traumatic brain injury (TBI) survivors often suffer chronically from significant morbidity associated with cognitive deficits, behavioral difficulties and a post-traumatic syndrome and thus it is important to understand the pathophysiology of these l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80e457ad8bf725f10f6b40d6672ca78
https://doi.org/10.1111/j.1460-9568.2008.06156.x
https://doi.org/10.1111/j.1460-9568.2008.06156.x
Autor:
Wendy M. Reid, Robert J. Hamm
Publikováno v:
Journal of Neurotrauma. 25:248-256
Catecholaminergic neurotransmission is regionally altered following injury, and drugs aimed at these systems offer promising avenues for post-traumatic brain injury (TBI) pharmacotherapies. Atomoxetine is a selective norepinephrine transporter (NET)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67c6ecfea88494913f97a1e22ceeaf3
https://doi.org/10.1089/neu.2007.0389
https://doi.org/10.1089/neu.2007.0389
Publikováno v:
Journal of Neurotrauma. 23:1233-1240
Chronic cognitive impairment is an enduring aspect of traumatic brain injury (TBI) in both humans and animals. Treating cognitive impairment in the post-traumatic stages of injury often involves the delivery of pharmacologic agents aimed at specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3f9b121f35d25869a7cd38f36cd2c6
https://doi.org/10.1089/neu.2006.23.1233
https://doi.org/10.1089/neu.2006.23.1233