Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Robert J Rooney"'
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107927 (2014)
After demonstrating, with karyotyping, polymerase chain reaction (PCR) and fluorescence in-situ hybridization, the retention of certain human chromosomes and genes following the spontaneous fusion of human tumor and hamster cells in-vivo, it was post
Externí odkaz:
https://doaj.org/article/73ab90565c7f4aa397e46d133d1489df
Autor:
Meenakshi Tiwary, Robert J. Rooney, Swantje Liedmann, Kim S. LeMessurier, Amali E. Samarasinghe
Publikováno v:
Cells, Vol 10, Iss 3, p 509 (2021)
Eosinophils, previously considered terminally differentiated effector cells, have multifaceted functions in tissues. We previously found that allergic mice with eosinophil-rich inflammation were protected from severe influenza and discovered speciali
Externí odkaz:
https://doaj.org/article/60618182d8cf48bfadecbc1947cba90d
Autor:
Robert J. Rooney
Publikováno v:
Gene
The 50 kDa N-terminal product of the cellular transcription factor E4F1 (p50E4F1) mediates E1A289R trans-activation of the adenovirus E4 gene, and suppresses E1A-mediated transformation by sensitizing cells to cell death. This report shows that while
Autor:
Kai C. Sonntag, Yenarae Lee, Noah D. McKenna, Yulei Wang, Filip Simunovic, Woori Kim, Robert J. Rooney, Benjamin Kong, Robert M. Stephens, Ming Yi, Hyemyung Seo
Publikováno v:
Neurobiology of Aging. 35:1712-1721
Dopamine (DA) neurons in sporadic Parkinson's disease (PD) display dysregulated gene expression networks and signaling pathways that are implicated in PD pathogenesis. Micro (mi)RNAs are regulators of gene expression, which could be involved in neuro
Autor:
Maribel P. Lim, Jill M. Goldstein, Martha E. Shenton, Larry J. Seidman, Kai-Christian Sonntag, Charmaine Y. Pietersen, Tsung-Ung W. Woo, Robert W. McCarley, Susie S. Kim, Tracey L. Petreyshen, Sarah A. Mauney, Robert J. Rooney, Eleonora Passeri
Publikováno v:
Journal of Neurogenetics. 28:70-85
Dysregulation of pyramidal cell network function by the soma- and axon-targeting inhibitory neurons that contain the calcium-binding protein parvalbumin (PV) represents a core pathophysiological feature of schizophrenia. In order to gain insight into
Autor:
Huda Y. Zoghbi, J. García, Robert J. Rooney, Nataliya Toporovskaya, Marija Cvetanovic, Puneet Opal
Publikováno v:
EMBO reports. 8:671-677
The leucine-rich acidic nuclear protein (LANP) belongs to the INHAT family of corepressors that inhibits histone acetyltransferases. The mechanism by which LANP restricts its repression to specific genes is unknown. Here, we report that LANP forms a
Autor:
Prerna Badhwar, Robert J. Rooney, Eve Diefenbach, Sarah Woodruff, Richard F. Kefford, Therese M. Becker, Helen Rizos
Publikováno v:
Journal of Biological Chemistry. 278:4981-4989
The p14(ARF) tumor suppressor is a key regulator of cellular proliferation and is frequently inactivated in human cancer. This tumor suppressor functions in the p53 and pRb cell cycle regulatory pathways and can effectively activate both pathways to
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 9, p e107927 (2014)
PLoS ONE, Vol 9, Iss 9, p e107927 (2014)
After demonstrating, with karyotyping, polymerase chain reaction (PCR) and fluorescence in-situ hybridization, the retention of certain human chromosomes and genes following the spontaneous fusion of human tumor and hamster cells in-vivo, it was post
Autor:
Loris De Cecco, Valentina Fogal, Robert J. Rooney, Claudio Schneider, Giannino Del Sal, Katalin Szalay, Monica Gostissa, Peter Sandy
Publikováno v:
Oncogene. 19:188-199
Control of cell growth and division by the p53 tumor suppressor protein requires its abilities to transactivate and repress specific target genes and to associate in complex with other proteins. Here we demonstrate that p53 binds to the E1A-regulated
Autor:
Robert J. Rooney, Stephan W. Morris, Douglas R. Higgs, Debra J. Gilbert, Neal G. Copeland, Rachael R. Daniels, Nancy A. Jenkins, Kristen Rothammer
Publikováno v:
Mammalian Genome. 9:320-323
'Department of Biochemistry, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, Tennessee 38105, USA 'Department of Experimental Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA 3MRC Molecular Haematology