Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Robert J Oliver"'
Publikováno v:
Journal of Experimental Neuroscience, Vol 12 (2018)
Addictive drugs effect the brain reward circuitry by altering functional plasticity of neurons governing the circuits. Relapse is an inherent problem in addicted subjects and is associated with neuroplasticity changes in several brain regions includi
Externí odkaz:
https://doaj.org/article/33d4b3a7eb3645079b618fa25b9f53a9
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
The RNA-binding protein (RBP) HuD is involved in neuronal differentiation, regeneration, synaptic plasticity and learning and memory. RBPs not only bind to mRNAs but also interact with several types of RNAs including circular RNAs (circRNAs), a class
Externí odkaz:
https://doaj.org/article/0d6754096d7c4ff185ff34a58792ed9c
Publikováno v:
Brain Sciences, Vol 9, Iss 11, p 330 (2019)
The dorsal striatum is important for the development of drug addiction; however, the role of dopamine D1 receptor (D1R) expressing medium-sized spiny striatonigral (direct pathway) neurons (D1-MSNs) in regulating excessive methamphetamine intake rema
Externí odkaz:
https://doaj.org/article/d5f2349eddda405ca0ab049553c9d841
Autor:
Yoshio Takashima, Joyee Tseng, McKenzie J. Fannon, Dvijen C. Purohit, Leon W. Quach, Michael J. Terranova, Khush M. Kharidia, Robert J. Oliver, Chitra D. Mandyam
Publikováno v:
Brain Sciences, Vol 8, Iss 12, p 208 (2018)
The present study examined differences in operant responses in adult male and female rats during distinct phases of addiction. Males and females demonstrated escalation in methamphetamine (0.05 mg/kg, i.v.) intake with females showing enhanced latenc
Externí odkaz:
https://doaj.org/article/f5fb3c7799844f29a86f1e13526e1029
Autor:
Robert J. Oliver
Publikováno v:
J Neurosci
Opioid reward has traditionally been thought to be mediated by GABA-induced disinhibition of dopamine (DA) neurons in the VTA. However, direct behavioral evidence supporting this hypothesis is still lacking. In this study, we found that the μ opioid
Autor:
Britta D. Sibley, Dvijen C. Purohit, Robert J. Oliver, Yosef Avchalumov, John J. Woodward, Chitra D. Mandyam, Candice Contet, Marisa Roberto, Wulfran Trenet, Rocio Erandi Heyer Osorno
Publikováno v:
Neuropharmacology
Alterations in the function of prefrontal cortex (PFC) and hippocampus have been implicated in underlying the relapse to alcohol seeking behaviors in humans and animal models of moderate to severe alcohol use disorders (AUD). Here we used chronic int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b70beb877111111b76182da79e15ef57
https://europepmc.org/articles/PMC7927349/
https://europepmc.org/articles/PMC7927349/
Autor:
Robert J. Oliver, Johnny A. Kenton, Wennonah Stevens, Nora I. Perrone-Bizzozero, Jonathan L. Brigman
Publikováno v:
Neuroscience Letters. 683:119-124
The neuronal RNA-binding protein HuD is involved in synaptic plasticity and the molecular mechanisms of learning and memory. Previously, we have shown that HuD is upregulated after both spatial and addiction-associated forms of learning, such as cond
Autor:
Khalid M. Qureshi, Robert J. Oliver, Michelle B. Paget, Hilary E. Murray, Clifford J. Bailey, Richard Downing
Publikováno v:
Cell Transplantation, Vol 20 (2011)
Chronic systemic immunosuppression in cell replacement therapy restricts its clinical application. This study sought to explore the potential of cell-based immune modulation as an alternative to immunosuppressive drug therapy in the context of pancre
Externí odkaz:
https://doaj.org/article/89a8acaa4eb84313ba4bab3fc0117e07
Autor:
Khush M. Kharidia, Robert J. Oliver, Chitra D. Mandyam, Joyee Tseng, Leon W. Quach, Yoshio Takashima, McKenzie J. Fannon, Dvijen C. Purohit, Michael J. Terranova
Publikováno v:
Brain Sciences
Volume 8
Issue 12
Brain Sciences, Vol 8, Iss 12, p 208 (2018)
Volume 8
Issue 12
Brain Sciences, Vol 8, Iss 12, p 208 (2018)
The present study examined differences in operant responses in adult male and female rats during distinct phases of addiction. Males and females demonstrated escalation in methamphetamine (0.05 mg/kg, i.v.) intake with females showing enhanced latenc
Autor:
Robert J. Oliver, Chitra D. Mandyam
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Frontiers in Neuroscience
Frontiers in Neuroscience
The discovery of non-coding RNAs (ncRNAs)has been one of the central findings from early genomic sequencing studies. Not only was the presence of these genes unknown previously, it was the staggering disproportionate share of the genome that was pred