Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Robert J McHale"'
Autor:
Kathrine Girrens, Matthew Macaluso, Megan M Dahmen, Faryal Ali, Ahsan Y. Khan, Robert J McHale
Publikováno v:
Journal of Psychiatric Practice. 16:289-296
Patients with schizophrenia have a greater incidence of being overweight or obese compared with the general population. Such individuals are often treated with second-generation (atypical) antipsychotics (SGAs), which are associated with weight gain,
Autor:
Kym C. Tolman, Carmine J. Coscia, Robert J. McHale, Michael D. Parnes, Gail E. Thomas, Julie A. McLachlan, Frank E. Johnson, Wojciech T. Bem, Mariana M. Belcheva, Jacob Barg, A. Ho
Publikováno v:
Journal of Neurochemistry. 63:570-574
Mouse N18TG2 neuroblastoma and rat C6 glioma cell lines were injected into male nude mice, and the tumors were passaged serially. At each generation, tumors were analyzed for delta opioid binding using [3H][D-Ala2,D-Leu5]enkephalin and for sigma 1 an
Autor:
A. Gorodinsky, Rivka Levy, Zvi Vogel, Carmine J. Coscia, Mariana M. Belcheva, Jacob Barg, Robert J. McHale
Publikováno v:
Journal of Neurochemistry. 65:1481-1486
Endorphins, enkephalins, and synthetic or naturally occurring exogenous opiates have been shown to affect the proliferation of neural cells (for reviews, see McDowell and Kitchen, 1987; Hammer and Hauser, 1992; Zagon and Slotkin, 1992; Leslie, 1993).
Publikováno v:
Analgesia. 1:294-297
Autor:
Carmine J. Coscia, Frank E. Johnson, Danielle Saya, Jacob Barg, Mariana M. Belcheva, Zvi Vogel, Robert J. McHale, Reuven Zimlichman, Rivka Levy
Publikováno v:
The Journal of Neuroscience. 14:5858-5864
Opioid agonists inhibit DNA synthesis in C6 rat glioma cells that express opioid receptors, induced by desipramine (DMI). This inhibition was not observed in cells that were not treated with DMI, and thus did not express opioid-binding sites. Endothe
Autor:
Julie A. McLachlan, Zvi Vogel, Robert J. McHale, Jacob Barg, Mariana M. Belcheva, Frank E. Johnson, Rivka Levy, Carmine J. Coscia
Publikováno v:
Glia. 10:10-15
Treatment of rat C6 glioma cells with the tricyclic antidepressant desipramine induces opioid binding. Here the distribution of these opioid-binding sites on C6 cell membranes and a functional property were investigated. Immunohistochemical examinati
Autor:
Regina Juszczak, Carmine J. Coscia, Kamran Khoobehi, Michael R. Hanley, Robert J. McHale, Maria Szücs, Eric A. Barnard, Mariana M. Belcheva, Tracy A. Donnigan, Wojciech T. Bem, Jacob Barg
Publikováno v:
Molecular Brain Research. 9:299-306
A mouse monoclonal, anti-idiotypic, anti-opioid receptor antibody (Ab2-AOR) has been generated from monoclonal anti-morphine antibodies (Ab1). Hybridoma culture supernatants were screened by a solid phase radioimmunoassay (RIA), based on their compet
Autor:
Carmine J. Coscia, Mariana M. Belcheva, Jacob Barg, Matthew T. Ho, Elena G. Ignatova, Samuel Dawn, Robert J. McHale
Publikováno v:
Brain research. Developmental brain research. 80(1-2)
Gestational actions of the mixed agonist-antagonist buprenorphine on μ-and κ 1 -opioid binding in neonatal and maternal rat brain were investigated. Upon exposure of pregnant rats to 0.5 mg/kg buprenorphine for 7 days prior to birth, postnatal day-
Publikováno v:
Brain research bulletin. 35(1)
Opioid antagonists such as naltrexone, naloxone, and ICI174864 induce a transient downregulation of delta opioid receptors prior to upregulation in NG108-15 cells. Here we show that naltrexone can also elicit a transient downregulation of delta 2 opi
Publikováno v:
Journal of natural products. 56(8)
An elicitation protocol, resulting in the accumulation of sanguinarine in suspension cultures of Papaver bracteatum, was assessed for induction of the same alkaloid in Sanguinaria canadensis. Although only a trace constituent of P. bracteatum plants,