Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Robert J Majeska"'
Autor:
Abigail A Coffman, Jelena Basta‐Pljakic, Rosa M Guerra, Frank H Ebetino, Mark W Lundy, Robert J Majeska, Mitchell B Schaffler
Publikováno v:
JBMR Plus, Vol 5, Iss 7, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/39b83b895613419fbd0d9763b0efaee3
Autor:
Abigail A Coffman, Jelena Basta‐Pljakic, Rosa M Guerra, Frank H Ebetino, Mark W Lundy, Robert J Majeska, Mitchell B Schaffler
Publikováno v:
JBMR Plus, Vol 5, Iss 4, Pp n/a-n/a (2021)
ABSTRACT Bisphosphonates (BPs) are a mainstay of osteoporosis treatment; however, concerns about bone health based on oversuppression of remodeling remain. Long‐term bone remodeling suppression adversely affects bone material properties with microd
Externí odkaz:
https://doaj.org/article/7379c21f04d841a7a77d926f4a2a7532
Autor:
Jonathan Y Lee, Zuping Zhou, Peter J Taub, Melissa Ramcharan, Yonghui Li, Takintope Akinbiyi, Edward R Maharam, Daniel J Leong, Damien M Laudier, Takuya Ruike, Phillip J Torina, Mone Zaidi, Robert J Majeska, Mitchell B Schaffler, Evan L Flatow, Hui B Sun
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17531 (2011)
We characterized the differentiation of rat bone marrow-derived mesenchymal stem cells (BM-MSCs) into tenocyte-like cells in response to bone morphogenetic protein-12 (BMP-12). BM-MSCs were prepared from Sprague-Dawley rats and cultured as monolayers
Externí odkaz:
https://doaj.org/article/ae65fd77be85486589f50a62da92add4
Autor:
Rosa M Guerra, Robert J. Majeska, Abigail A Coffman, Mitchell B. Schaffler, Mark W Lundy, Jelena Basta-Pljakic, Frank H. Ebetino
Publikováno v:
JBMR Plus, Vol 5, Iss 4, Pp n/a-n/a (2021)
JBMR Plus
JBMR Plus
Bisphosphonates (BPs) are a mainstay of osteoporosis treatment; however, concerns about bone health based on oversuppression of remodeling remain. Long‐term bone remodeling suppression adversely affects bone material properties with microdamage acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80297482979bcf35bdd0d3bf4438820b
https://doi.org/10.1002/jbm4.10476
https://doi.org/10.1002/jbm4.10476
Autor:
Mia M. Thi, Karl J. Lewis, Zeynep Seref-Ferlengez, Samuel Stephen, Sheldon Weinbaum, David C. Spray, Joyce Louie, Robert J. Majeska, Pamela Cabahug-Zuckerman, James F. Boorman-Padgett, Mitchell B. Schaffler, Jelena Basta-Pljakic
Publikováno v:
Bone
Microstructural adaptation of bone in response to mechanical stimuli is diminished with estrogen deprivation. Here we tested in vivo whether ovariectomy (OVX) alters the acute response of osteocytes, the principal mechanosensory cells of bone, to mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afdaa1ba18844bc2821f38ef48d3a60a
https://doi.org/10.1016/j.bone.2021.116072
https://doi.org/10.1016/j.bone.2021.116072
Autor:
Sheldon Weinbaum, Dorra Frikha-Benayed, Samuel Stephen, Karl J. Lewis, Mitchell B. Schaffler, Mia M. Thi, Robert J. Majeska, Joyce Louie, Zeynep Seref-Ferlengez, David C. Spray
Publikováno v:
Proceedings of the National Academy of Sciences. 114:11775-11780
Osteocytes are considered to be the major mechanosensory cells of bone, but how osteocytes in vivo process, perceive, and respond to mechanical loading remains poorly understood. Intracellular calcium (Ca2+) signaling resulting from mechanical stimul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5827b43dffa3d49fb8783aa04061b41f
https://doi.org/10.1073/pnas.1707863114
https://doi.org/10.1073/pnas.1707863114
Autor:
Carol R. Flach, Serra Kaya, Luis Cardoso, Qihong Zhang, Robert J. Majeska, Shoshana Yakar, Timothy G. Bromage, Susannah P. Fritton, Jelena Basta-Pljakic, Richard Mendelsohn, Zeynep Seref-Ferlengez, Mitchell B. Schaffler
Publikováno v:
Journal of Bone and Mineral Research. 32:688-697
During lactation, mammals resorb mineral from the maternal skeleton to provide calcium to milk. Rodents lose 25% to 35% of skeletal ash weight, ash calcium content, and bone mineral content as measured by dual-energy X-ray absorptiometry (DXA), and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5b25fabd1e6a70d4925a9ca96c531e
https://doi.org/10.1002/jbmr.3044
https://doi.org/10.1002/jbmr.3044
Publikováno v:
Cells
Volume 8
Issue 10
Cells, Vol 8, Iss 10, p 1301 (2019)
Volume 8
Issue 10
Cells, Vol 8, Iss 10, p 1301 (2019)
Regenerative retinal therapies have introduced progenitor cells to replace dysfunctional or injured neurons and regain visual function. While contemporary cell replacement therapies have delivered retinal progenitor cells (RPCs) within customized bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb08e1cafc4f8181aceb51c3cbe56b2
http://europepmc.org/articles/PMC6829900
http://europepmc.org/articles/PMC6829900
Publikováno v:
J Bone Miner Res
Localized apoptosis of osteocytes, the tissue-resident cells within bone, occurs with fatigue microdamage and activates bone resorption. Osteoclasts appear to target and remove dying osteocytes, resorbing damaged bone matrix as well. Osteocyte apopto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::812a44bc7dea2322454bfff6f83639d8
https://pubmed.ncbi.nlm.nih.gov/31910292
https://pubmed.ncbi.nlm.nih.gov/31910292
Autor:
David M. Hirsh, Lin Xu, Daniel J. Leong, Robert J. Majeska, Sun J. Kim, Zhiyong He, Hui B. Sun, Mary B. Goldring, Neil J. Cobelli, Lidi Liu, Haotian Feng, Laijin Lu
Publikováno v:
Annals of the New York Academy of Sciences. 1442(1)
Adipokines secreted from the infrapatellar fat pad (IPFP), such as adipsin and adiponectin, have been implicated in osteoarthritis pathogenesis. CITED2, a mechanosensitive transcriptional regulator with chondroprotective activity, may modulate their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3ed5156125c2c64ef6c0c45be5e70f
https://pubmed.ncbi.nlm.nih.gov/30891782
https://pubmed.ncbi.nlm.nih.gov/30891782