Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Robert J Kemppainen"'
Autor:
Huifei Sophia Zheng, Jeffrey G Daniel, Julia M Salamat, Laci Mackay, Chad D Foradori, Robert J Kemppainen, Satyanarayana R Pondugula, Ya-Xiong Tao, Chen-Che Jeff Huang
Publikováno v:
Endocrine Connections, Vol 11, Iss 8, Pp 1-13 (2022)
Glucocorticoids have short- and long-term effects on adrenal gland function and development. RNA sequencing (RNA-seq) was performed to identify early transcriptomic responses to the synthetic glucocorticoid, dexamethasone (Dex), in vitro and in vivo.
Externí odkaz:
https://doaj.org/article/86f3298876c94dcc8256fdf11454cfcd
Publikováno v:
Stress
Dexamethasone-induced Ras-related protein 1 (Rasd1) is a member of the Ras superfamily of monomeric G proteins that have a regulatory function in signal transduction. Rasd1, also known as Dexras1 or AGS1, is rapidly induced by dexamethasone (Dex). Wh
Autor:
Robert J. Kemppainen
Publikováno v:
Clinical Small Animal Internal Medicine
Publikováno v:
J Vet Diagn Invest
The addition of ethylenediamine tetra-acetic acid (EDTA) to serum can affect the measurement of cortisol by chemiluminescent enzyme immunoassay (CEIA); addition of magnesium chloride (MgCl2) may reverse the effects. However, similar characteristics f
Autor:
Ellen N. Behrend, Annabel N. Botsford, Frank Oprandy, Philippe Gaillard, Robert J. Kemppainen, Hollie P. Lee
Publikováno v:
Journal of Veterinary Internal Medicine
Background Low-dose ACTH stimulation testing would lower cost and may increase sensitivity for identification of partial ACTH deficiency. Hypothesis (1) The low-dose ACTH stimulation test will provide comparable results to the standard-dose ACTH stim
Autor:
Jessica E. Healy, B. Douglas White, Melaney A Jones, Laura R. Hinds, Casey C. Read, Kun Don Yi, Chad D. Foradori, Alicia M. Quihuis, Robert J. Handa, Anthony F. Lacagnina, Arthur D. Zimmerman, Robert J. Kemppainen, Charles B. Breckenridge
Publikováno v:
Endocrinology. 159:3378-3388
Atrazine (ATR) is a commonly used pre-emergence and early postemergence herbicide. Rats gavaged with ATR and its chlorometabolites desethylatrazine (DEA) and deisopropylatrazine (DIA) respond with a rapid and dose-dependent rise in plasma corticoster
Publikováno v:
Journal of Veterinary Diagnostic Investigation. 30:438-441
Hormone assays that use a solid-phase, automated, chemiluminescent enzyme immunoassay (CEIA) with an alkaline phosphatase–tagged hormone or antibody as a reporter are performed on serum or EDTA plasma in our laboratory. CEIA cortisol results appear
Autor:
Olgica Ceric, Mark Glover, Lauren Carey, Lee Anne Palmer, Robert J. Kemppainen, April Hodges, John P. Buchweitz, Renate Reimschuessel, William Burkholder, Lynn O. Post, Elizabeth Edwards, Sarah M. Nemser, Krisztina Wolf, Enrique G. Yanes, Sonya Lambkin, Doug Heitkemper, Robert Wilson, Kent R. Refsal, David Rotstein, Caroline Wilkinson, Jennifer L. Jones, Randall A. Lovell
Publikováno v:
Topics in Companion Animal Medicine. 43:100521
Dietary exogenous thyrotoxicosis is infrequently observed in pet food. A retrospective evaluation of pet food investigations (PFI) was conducted for 17 dogs, including review of medical records, dietary and environmental exposure interviews, food tes
Autor:
Lee Palmer, Robert J. Kemppainen, Linda G. Martin, Emily J. Skovira, Ellen N. Behrend, Hollie P. Lee
Publikováno v:
American Journal of Veterinary Research. 78:919-925
OBJECTIVE To assess effects of major abdominal surgery on serum cortisol and aldosterone and plasma canine ACTH (cACTH) concentrations. ANIMALS 39 healthy dogs undergoing laparotomy during veterinary student surgical laboratories. PROCEDURES Blood sa
Autor:
Jeff Daniel, Huifei Sophia Zheng, Chad D. Foradori, Chen-Che Jeff Huang, Robert J. Kemppainen
Publikováno v:
Journal of the Endocrine Society
Researchers have long known that dexamethasone causes cellular and functional changes in the adrenal gland. For example, long-term dexamethasone treatment leads to reversible adrenal cortex atrophy. In the adrenal medulla, dexamethasone treatment alt