Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Robert J Johnston"'
Autor:
Sarah E Hadyniak, Joanna F D Hagen, Kiara C Eldred, Boris Brenerman, Katarzyna A Hussey, Rajiv C McCoy, Michael E G Sauria, James A Kuchenbecker, Thomas Reh, Ian Glass, Maureen Neitz, Jay Neitz, James Taylor, Robert J Johnston
Publikováno v:
PLoS Biology, Vol 22, Iss 1, p e3002464 (2024)
Trichromacy is unique to primates among placental mammals, enabled by blue (short/S), green (medium/M), and red (long/L) cones. In humans, great apes, and Old World monkeys, cones make a poorly understood choice between M and L cone subtype fates. To
Externí odkaz:
https://doaj.org/article/1f0475e47bdc4d9385fdd1053392dcb8
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 3, p e1007691 (2020)
Nervous systems are incredibly diverse, with myriad neuronal subtypes defined by gene expression. How binary and graded fate characteristics are patterned across tissues is poorly understood. Expression of opsin photopigments in the cone photorecepto
Externí odkaz:
https://doaj.org/article/fac39a1186d043e78a0fc1d01a28b41d
Autor:
Caitlin Anderson, India Reiss, Cyrus Zhou, Annie Cho, Haziq Siddiqi, Benjamin Mormann, Cameron M Avelis, Peter Deford, Alan Bergland, Elijah Roberts, James Taylor, Daniel Vasiliauskas, Robert J Johnston
Publikováno v:
eLife, Vol 6 (2017)
Each individual perceives the world in a unique way, but little is known about the genetic basis of variation in sensory perception. In the fly eye, the random mosaic of color-detecting R7 photoreceptor subtypes is determined by stochastic on/off exp
Externí odkaz:
https://doaj.org/article/dd44de8dbd1743dca211e319e85039e7
Autor:
Mark J Selby, John J Engelhardt, Robert J Johnston, Li-Sheng Lu, Minhua Han, Kent Thudium, Dapeng Yao, Michael Quigley, Jose Valle, Changyu Wang, Bing Chen, Pina M Cardarelli, Diann Blanset, Alan J Korman
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0167251 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0161779.].
Externí odkaz:
https://doaj.org/article/96849ae8f269431fa5d720767c21f010
Autor:
Mark J Selby, John J Engelhardt, Robert J Johnston, Li-Sheng Lu, Minhua Han, Kent Thudium, Dapeng Yao, Michael Quigley, Jose Valle, Changyu Wang, Bing Chen, Pina M Cardarelli, Diann Blanset, Alan J Korman
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0161779 (2016)
The monoclonal antibodies ipilimumab (anti-CTLA-4) and nivolumab (anti-PD-1) have shown remarkable antitumor activity in an increasing number of cancers. When combined, ipilimumab and nivolumab have demonstrated superior activity in patients with met
Externí odkaz:
https://doaj.org/article/e4cbf86cb6a84748be5b341a365cb284
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83457 (2013)
Epstein-Barr virus induced receptor 2 (EBI2), a Gαi-coupled G protein-coupled receptor, is a chemotactic receptor for B, T and dendritic cells (DC). Genetic studies have also implicated EBI2 as a regulator of an interferon regulatory factor 7 (IRF7)
Externí odkaz:
https://doaj.org/article/dae4ec9125314ff48442f1cf9a32929c
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 2, p e1002357 (2012)
The photoreceptors of the Drosophila compound eye are a classical model for studying cell fate specification. Photoreceptors (PRs) are organized in bundles of eight cells with two major types - inner PRs involved in color vision and outer PRs involve
Externí odkaz:
https://doaj.org/article/2ea41f69c0c34afda201b21de5d6cf3e
Autor:
Esteban O Mazzoni, Arzu Celik, Mathias F Wernet, Daniel Vasiliauskas, Robert J Johnston, Tiffany A Cook, Franck Pichaud, Claude Desplan
Publikováno v:
PLoS Biology, Vol 6, Iss 4, p e97 (2008)
The Drosophila eye is a mosaic that results from the stochastic distribution of two ommatidial subtypes. Pale and yellow ommatidia can be distinguished by the expression of distinct rhodopsins and other pigments in their inner photoreceptors (R7 and
Externí odkaz:
https://doaj.org/article/aa2f88f88c6e409499fc052438e11f7c
Autor:
Ying V. Liu, Clayton P. Santiago, Akin Sogunro, Gregory J. Konar, Ming-wen Hu, Minda M. McNally, Yu-chen Lu, Miguel Flores-Bellver, Silvia Aparicio-Domingo, Kang V. Li, Zhuo-lin Li, Dzhalal Agakishiev, Sarah E. Hadyniak, Katarzyna A. Hussey, Tyler J. Creamer, Linda D. Orzolek, Derek Teng, M. Valeria Canto-Soler, Jiang Qian, Zheng Jiang, Robert J. Johnston, Seth Blackshaw, Mandeep S. Singh
Publikováno v:
Stem Cell Reports. 18:1138-1154
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c82f9b964ca622ecf3a99f27e8d74a50
https://doi.org/10.1016/j.stemcr.2023.04.004
https://doi.org/10.1016/j.stemcr.2023.04.004
Publikováno v:
Dev Biol
Across eumetazoans, the ability to perceive and respond to visual stimuli is largely mediated by opsins, a family of proteins belonging to the G protein-coupled receptor (GPCR) superclass. Lineage-specific gains and losses led to a striking diversity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c5eb25da20816d434264104ad48e7f
https://doi.org/10.1016/j.ydbio.2022.10.011
https://doi.org/10.1016/j.ydbio.2022.10.011