Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Robert J Homer"'
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147588 (2016)
The role of vascular endothelial growth factor (VEGF)-induced 3 different nitric oxide synthase (NOS) isoforms in lung development and injury in the newborn (NB) lung are not known. We hypothesized that VEGF-induced specific NOS pathways are critical
Externí odkaz:
https://doaj.org/article/2f9d5af5d76f49db9e72e63992b1599e
Autor:
Huanxing Sun, Rayman Choo-Wing, Angara Sureshbabu, Juan Fan, Lin Leng, Shuang Yu, Dianhua Jiang, Paul Noble, Robert J Homer, Richard Bucala, Vineet Bhandari
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60560 (2013)
The role and mechanism of action of MIF in hyperoxia-induced acute lung injury (HALI) in the newborn lung are not known. We hypothesized that MIF is a critical regulatory molecule in HALI in the developing lung.We studied newborn wild type (WT), MIF
Externí odkaz:
https://doaj.org/article/841002c3c16a44848b2662039eb64e4f
Autor:
Robert Camp, Maxwell L. Smith, Brandon T. Larsen, Anja C. Roden, Carol Farver, Andre L. Moreira, Richard Attanoos, Raghavendra Pillappa, Irene Sansano, Alexandre Todorovic Fabro, Robert J. Homer
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Current interstitial lung disease (ILD) diagnostic guidelines assess criteria across clinical, radiologic and pathologic domains. Significant interobserver variation in histopathologic evaluation has previously been shown but the
Externí odkaz:
https://doaj.org/article/59d0209d00e74ffe976371282aa60c7d
Autor:
Camila Robles-Oteiza, Deborah Ayeni, Stellar Levy, Robert J. Homer, Susan M. Kaech, Katerina Politi
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 11 (2021)
Conditional ablation of defined cell populations in vivo can be achieved using genetically engineered mice in which the human diphtheria toxin (DT) receptor (DTR) is placed under control of a murine tissue-specific promotor, such that delivery of DT
Externí odkaz:
https://doaj.org/article/d4f0aefa005e4a42a25399005ca41bcb
Autor:
Hrishikesh S. Kulkarni, Janet S. Lee, Julie A. Bastarache, Wolfgang M. Kuebler, Gregory P. Downey, Guillermo M. Albaiceta, William A. Altemeier, Antonio Artigas, Jason H. T. Bates, Carolyn S. Calfee, Charles S. Dela Cruz, Robert P. Dickson, Joshua A. Englert, Jeffrey I. Everitt, Michael B. Fessler, Andrew E. Gelman, Kymberly M. Gowdy, Steve D. Groshong, Susanne Herold, Robert J. Homer, Jeffrey C. Horowitz, Connie C. W. Hsia, Kiyoyasu Kurahashi, Victor E. Laubach, Mark R. Looney, Rudolf Lucas, Nilam S. Mangalmurti, Anne M. Manicone, Thomas R. Martin, Sadis Matalon, Michael A. Matthay, Daniel F. McAuley, Sharon A. McGrath-Morrow, Joseph P. Mizgerd, Stephanie A. Montgomery, Bethany B. Moore, Alexandra Noël, Carrie E. Perlman, John P. Reilly, Eric P. Schmidt, Shawn J. Skerrett, Tomeka L. Suber, Charlotte Summers, Benjamin T. Suratt, Masao Takata, Rubin Tuder, Stefan Uhlig, Martin Witzenrath, Rachel L. Zemans, Gutavo Matute-Bello
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 66:e1-e14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74839f7126fbd7a58c1527ef783f44f4
https://doi.org/10.1165/rcmb.2021-0531st
https://doi.org/10.1165/rcmb.2021-0531st
Autor:
David L. Rimm, Frank Detterbeck, Daniel Boffa, Robert J. Homer, Scott Gettinger, Lynn Tanoue, Konstantinos N. Syrigos, Gerold Bepler, Valsamo K. Anagnostou
Supplementary Data from High Expression of Mammalian Target of Rapamycin Is Associated with Better Outcome for Patients with Early Stage Lung Adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61650e8e99b95720a94c635a2360aa7f
https://doi.org/10.1158/1078-0432.22440174.v1
https://doi.org/10.1158/1078-0432.22440174.v1
Autor:
David L. Rimm, Frank Detterbeck, Daniel Boffa, Robert J. Homer, Scott Gettinger, Lynn Tanoue, Konstantinos N. Syrigos, Gerold Bepler, Valsamo K. Anagnostou
Purpose: Mammalian target of rapamycin (mTOR) is a key kinase downstream of phosphoinositide 3-kinase (PI3K)/AKT predominantly involved in translational control in the presence of nutrients and energy. Despite the well known role of mTOR in carcinoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2365035fdf97c534b3e8853620fd64a
https://doi.org/10.1158/1078-0432.c.6517542
https://doi.org/10.1158/1078-0432.c.6517542
Autor:
Tianyang Mao, Benjamin Israelow, Mario A. Peña-Hernández, Alexandra Suberi, Liqun Zhou, Sophia Luyten, Melanie Reschke, Huiping Dong, Robert J. Homer, W. Mark Saltzman, Akiko Iwasaki
Publikováno v:
Science (New York, N.Y.). 378(6622)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has highlighted the need for vaccines that not only prevent disease but also prevent transmission. Parenteral vaccines induce robust systemic immunity but poor immunity at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4cc222314008b7dd881bf92fe48c9ca
https://pubmed.ncbi.nlm.nih.gov/35118464
https://pubmed.ncbi.nlm.nih.gov/35118464
Autor:
Nicholas E. Banovich, Robert Lafyatis, Laura E. Niklason, Kerstin B. Meyer, Dana Pe'er, Carlos Cosme, Yifan Yuan, Taylor Adams, Austin J. Gutierrez, Maor Sauler, Maurizio Chioccioli, Kadi-Ann Rose, Edward P. Manning, Jonathan A. Kropski, Sergio Poli, Norihito Omote, Xiting Yan, Farida Ahangari, Nir Neumark, Jonas C. Schupp, Arun C. Habermann, Richard W. Pierce, Linh T. Bui, Giuseppe DeIuliis, Micha Sam Brickman Raredon, Martijn C. Nawijn, Robert J. Homer, Naftali Kaminski, Ivan O. Rosas, Sarah A. Teichmann
Publikováno v:
Circulation, 144(4), 286-302. LIPPINCOTT WILLIAMS & WILKINS
Circulation
Circulation
Supplemental Digital Content is available in the text.
Background: Cellular diversity of the lung endothelium has not been systematically characterized in humans. We provide a reference atlas of human lung endothelial cells (ECs) to facilitate a
Background: Cellular diversity of the lung endothelium has not been systematically characterized in humans. We provide a reference atlas of human lung endothelial cells (ECs) to facilitate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce2efbc3105bc22498151ccb2783db9
https://hdl.handle.net/11370/d5753d65-37c1-4e75-9af3-ca9b24311427
https://hdl.handle.net/11370/d5753d65-37c1-4e75-9af3-ca9b24311427
Autor:
Dmitri A. Petrov, Jessica A. Hellyer, Jungmin Choi, Giorgia Foggetti, Laura Andrejka, Chuan Li, Scott N. Gettinger, Deborah Ayeni, Hongchen Cai, Stellar Levy, Wen-Yang Lin, Robert J. Homer, Heather A. Wakelee, Nicholas Rashleigh, Katherine Hastings, Maximilian Diehn, Monte M. Winslow, Katerina Politi, Anna Wurtz, Dylan Maghini
Publikováno v:
Cancer Discov
In lung adenocarcinoma, oncogenic EGFR mutations co-occur with many tumor suppressor gene alterations; however, the extent to which these contribute to tumor growth and response to therapy in vivo remains largely unknown. By quantifying the effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e22d67bb0ab7ce573a4edcfa1b9097b
https://doi.org/10.1158/2159-8290.cd-20-1385
https://doi.org/10.1158/2159-8290.cd-20-1385