Zobrazeno 1 - 10
of 304
pro vyhledávání: '"Robert J Homer"'
Autor:
Robert Camp, Maxwell L. Smith, Brandon T. Larsen, Anja C. Roden, Carol Farver, Andre L. Moreira, Richard Attanoos, Raghavendra Pillappa, Irene Sansano, Alexandre Todorovic Fabro, Robert J. Homer
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Current interstitial lung disease (ILD) diagnostic guidelines assess criteria across clinical, radiologic and pathologic domains. Significant interobserver variation in histopathologic evaluation has previously been shown but the
Externí odkaz:
https://doaj.org/article/59d0209d00e74ffe976371282aa60c7d
Autor:
Camila Robles-Oteiza, Deborah Ayeni, Stellar Levy, Robert J. Homer, Susan M. Kaech, Katerina Politi
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 11 (2021)
Conditional ablation of defined cell populations in vivo can be achieved using genetically engineered mice in which the human diphtheria toxin (DT) receptor (DTR) is placed under control of a murine tissue-specific promotor, such that delivery of DT
Externí odkaz:
https://doaj.org/article/d4f0aefa005e4a42a25399005ca41bcb
Autor:
Matteo Forloni, Romi Gupta, Arvindhan Nagarajan, Li-Sha Sun, Yuying Dong, Valentina Pirazzoli, Maria Toki, Anna Wurtz, Mary Ann Melnick, Susumu Kobayashi, Robert J. Homer, David L. Rimm, Scott J. Gettinger, Katerina Politi, Shaillay Kumar Dogra, Narendra Wajapeyee
Publikováno v:
Cell Reports, Vol 16, Iss 2, Pp 457-471 (2016)
Oncogene-induced DNA methylation-mediated transcriptional silencing of tumor suppressors frequently occurs in cancer, but the mechanism and functional role of this silencing in oncogenesis are not fully understood. Here, we show that oncogenic epider
Externí odkaz:
https://doaj.org/article/15a64a7222eb429dac304c87c01334c5
Autor:
Hrishikesh S. Kulkarni, Janet S. Lee, Julie A. Bastarache, Wolfgang M. Kuebler, Gregory P. Downey, Guillermo M. Albaiceta, William A. Altemeier, Antonio Artigas, Jason H. T. Bates, Carolyn S. Calfee, Charles S. Dela Cruz, Robert P. Dickson, Joshua A. Englert, Jeffrey I. Everitt, Michael B. Fessler, Andrew E. Gelman, Kymberly M. Gowdy, Steve D. Groshong, Susanne Herold, Robert J. Homer, Jeffrey C. Horowitz, Connie C. W. Hsia, Kiyoyasu Kurahashi, Victor E. Laubach, Mark R. Looney, Rudolf Lucas, Nilam S. Mangalmurti, Anne M. Manicone, Thomas R. Martin, Sadis Matalon, Michael A. Matthay, Daniel F. McAuley, Sharon A. McGrath-Morrow, Joseph P. Mizgerd, Stephanie A. Montgomery, Bethany B. Moore, Alexandra Noël, Carrie E. Perlman, John P. Reilly, Eric P. Schmidt, Shawn J. Skerrett, Tomeka L. Suber, Charlotte Summers, Benjamin T. Suratt, Masao Takata, Rubin Tuder, Stefan Uhlig, Martin Witzenrath, Rachel L. Zemans, Gutavo Matute-Bello
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 66:e1-e14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74839f7126fbd7a58c1527ef783f44f4
https://doi.org/10.1165/rcmb.2021-0531st
https://doi.org/10.1165/rcmb.2021-0531st
Autor:
David L. Rimm, Frank Detterbeck, Daniel Boffa, Robert J. Homer, Scott Gettinger, Lynn Tanoue, Konstantinos N. Syrigos, Gerold Bepler, Valsamo K. Anagnostou
Supplementary Data from High Expression of Mammalian Target of Rapamycin Is Associated with Better Outcome for Patients with Early Stage Lung Adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61650e8e99b95720a94c635a2360aa7f
https://doi.org/10.1158/1078-0432.22440174.v1
https://doi.org/10.1158/1078-0432.22440174.v1
Autor:
David L. Rimm, Frank Detterbeck, Daniel Boffa, Robert J. Homer, Scott Gettinger, Lynn Tanoue, Konstantinos N. Syrigos, Gerold Bepler, Valsamo K. Anagnostou
Purpose: Mammalian target of rapamycin (mTOR) is a key kinase downstream of phosphoinositide 3-kinase (PI3K)/AKT predominantly involved in translational control in the presence of nutrients and energy. Despite the well known role of mTOR in carcinoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2365035fdf97c534b3e8853620fd64a
https://doi.org/10.1158/1078-0432.c.6517542
https://doi.org/10.1158/1078-0432.c.6517542
Autor:
Tianyang Mao, Benjamin Israelow, Mario A. Peña-Hernández, Alexandra Suberi, Liqun Zhou, Sophia Luyten, Melanie Reschke, Huiping Dong, Robert J. Homer, W. Mark Saltzman, Akiko Iwasaki
Publikováno v:
Science (New York, N.Y.). 378(6622)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has highlighted the need for vaccines that not only prevent disease but also prevent transmission. Parenteral vaccines induce robust systemic immunity but poor immunity at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4cc222314008b7dd881bf92fe48c9ca
https://pubmed.ncbi.nlm.nih.gov/35118464
https://pubmed.ncbi.nlm.nih.gov/35118464
Autor:
Nicholas E. Banovich, Robert Lafyatis, Laura E. Niklason, Kerstin B. Meyer, Dana Pe'er, Carlos Cosme, Yifan Yuan, Taylor Adams, Austin J. Gutierrez, Maor Sauler, Maurizio Chioccioli, Kadi-Ann Rose, Edward P. Manning, Jonathan A. Kropski, Sergio Poli, Norihito Omote, Xiting Yan, Farida Ahangari, Nir Neumark, Jonas C. Schupp, Arun C. Habermann, Richard W. Pierce, Linh T. Bui, Giuseppe DeIuliis, Micha Sam Brickman Raredon, Martijn C. Nawijn, Robert J. Homer, Naftali Kaminski, Ivan O. Rosas, Sarah A. Teichmann
Publikováno v:
Circulation, 144(4), 286-302. LIPPINCOTT WILLIAMS & WILKINS
Circulation
Circulation
Supplemental Digital Content is available in the text.
Background: Cellular diversity of the lung endothelium has not been systematically characterized in humans. We provide a reference atlas of human lung endothelial cells (ECs) to facilitate a
Background: Cellular diversity of the lung endothelium has not been systematically characterized in humans. We provide a reference atlas of human lung endothelial cells (ECs) to facilitate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce2efbc3105bc22498151ccb2783db9
https://hdl.handle.net/11370/d5753d65-37c1-4e75-9af3-ca9b24311427
https://hdl.handle.net/11370/d5753d65-37c1-4e75-9af3-ca9b24311427
Autor:
Dmitri A. Petrov, Jessica A. Hellyer, Jungmin Choi, Giorgia Foggetti, Laura Andrejka, Chuan Li, Scott N. Gettinger, Deborah Ayeni, Hongchen Cai, Stellar Levy, Wen-Yang Lin, Robert J. Homer, Heather A. Wakelee, Nicholas Rashleigh, Katherine Hastings, Maximilian Diehn, Monte M. Winslow, Katerina Politi, Anna Wurtz, Dylan Maghini
Publikováno v:
Cancer Discov
In lung adenocarcinoma, oncogenic EGFR mutations co-occur with many tumor suppressor gene alterations; however, the extent to which these contribute to tumor growth and response to therapy in vivo remains largely unknown. By quantifying the effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e22d67bb0ab7ce573a4edcfa1b9097b
https://doi.org/10.1158/2159-8290.cd-20-1385
https://doi.org/10.1158/2159-8290.cd-20-1385
Autor:
Marina K. Baine, Christopher A. Febres-Aldana, Jason C. Chang, Achim A. Jungbluth, Shenon Sethi, Cristina R. Antonescu, William D. Travis, Min-Shu Hsieh, Mee Sook Roh, Robert J. Homer, Marc Ladanyi, Jacklynn V. Egger, W. Victoria Lai, Charles M. Rudin, Natasha Rekhtman
Publikováno v:
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 17(9)
POU2F3 is a recent marker of a small cell lung carcinoma (SCLC) subtype related to chemosensory tuft cells (SCLC-P). The characteristics of SCLC-P have not been fully defined, and the data on POU2F3 expression in other lung tumors are scarce.We scree
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e0cddb150622ca4ce11a94cb603965
https://pubmed.ncbi.nlm.nih.gov/36031286
https://pubmed.ncbi.nlm.nih.gov/36031286