Zobrazeno 1 - 10
of 690
pro vyhledávání: '"Robert J Gillies"'
Autor:
Lei Jiang, Jie Tian, Wei Mu, Evangelia Katsoulakis, Ilke Tunali, Jhanelle E Gray, Robert J Gillies
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Background Currently, only a fraction of patients with non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors (ICIs) experience a durable clinical benefit (DCB). According to NCCN guidelines, Programmed death-ligand 1 (PD-L1) ex
Externí odkaz:
https://doaj.org/article/59db790823eb4a3498c3766b684d1692
Autor:
Lei Jiang, Jie Tian, Wei Mu, Evangelia Katsoulakis, Ilke Tunali, Jhanelle E Gray, Robert J Gillies
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 6 (2021)
Externí odkaz:
https://doaj.org/article/df257b2ff94b42f9834a6de045814fbd
Autor:
Olya Grove, Anders E Berglund, Matthew B Schabath, Hugo J W L Aerts, Andre Dekker, Hua Wang, Emmanuel Rios Velazquez, Philippe Lambin, Yuhua Gu, Yoganand Balagurunathan, Edward Eikman, Robert A Gatenby, Steven Eschrich, Robert J Gillies
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248541 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0118261.].
Externí odkaz:
https://doaj.org/article/92f46502f45b4738906c8ef62e7d448b
Autor:
Jung W Choi, Mikalai Budzevich, Shaowei Wang, Kenneth Gage, Veronica Estrella, Robert J Gillies
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0211012 (2019)
99m-Technetium-labeled (99mTc) erythrocyte imaging with planar scintigraphy is widely used for evaluating both patients with occult gastrointestinal bleeding and patients at risk for chemotherapy-induced cardiotoxicity. While a number of alternative
Externí odkaz:
https://doaj.org/article/936e253d352040e09a103bdc330be91f
Autor:
Ahmed Hosny, Chintan Parmar, Thibaud P Coroller, Patrick Grossmann, Roman Zeleznik, Avnish Kumar, Johan Bussink, Robert J Gillies, Raymond H Mak, Hugo J W L Aerts
Publikováno v:
PLoS Medicine, Vol 15, Iss 11, p e1002711 (2018)
BackgroundNon-small-cell lung cancer (NSCLC) patients often demonstrate varying clinical courses and outcomes, even within the same tumor stage. This study explores deep learning applications in medical imaging allowing for the automated quantificati
Externí odkaz:
https://doaj.org/article/597e8d8469de4a66ab0cbec960827863
Autor:
Patrick Grossmann, Olya Stringfield, Nehme El-Hachem, Marilyn M Bui, Emmanuel Rios Velazquez, Chintan Parmar, Ralph TH Leijenaar, Benjamin Haibe-Kains, Philippe Lambin, Robert J Gillies, Hugo JWL Aerts
Publikováno v:
eLife, Vol 6 (2017)
Medical imaging can visualize characteristics of human cancer noninvasively. Radiomics is an emerging field that translates these medical images into quantitative data to enable phenotypic profiling of tumors. While radiomics has been associated with
Externí odkaz:
https://doaj.org/article/79344e6bef3445a891fa35a2b1266c1d
Autor:
Jennifer M Rothberg, Kate M Bailey, Jonathan W Wojtkowiak, Yael Ben-Nun, Matthew Bogyo, Ekkehard Weber, Kamiar Moin, Galia Blum, Raymond R Mattingly, Robert J Gillies, Bonnie F Sloane
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 10, Pp 1125-1137 (2013)
One of the noncellular microenvironmental factors that contribute to malignancy of solid tumors is acidic peritumoral pH. We have previously demonstrated that extracellular acidosis leads to localization of the cysteine pro-tease cathepsin B on the t
Externí odkaz:
https://doaj.org/article/936d7cbb60d84915842ded87518a6e67
Autor:
Matthew B Schabath, Pierre P Massion, Zachary J Thompson, Steven A Eschrich, Yoganand Balagurunathan, Dmitry Goldof, Denise R Aberle, Robert J Gillies
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0159880 (2016)
Lung cancer screening identifies cancers with heterogeneous behaviors. Some lung cancers will be identified among patients who had prior negative CT screens and upon follow-up scans develop a de novo nodule that was determined to be cancerous. Other
Externí odkaz:
https://doaj.org/article/75d23456d7c548a69e9cc45ec03c319f
Autor:
Olya Grove, Anders E Berglund, Matthew B Schabath, Hugo J W L Aerts, Andre Dekker, Hua Wang, Emmanuel Rios Velazquez, Philippe Lambin, Yuhua Gu, Yoganand Balagurunathan, Edward Eikman, Robert A Gatenby, Steven Eschrich, Robert J Gillies
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118261 (2015)
Two CT features were developed to quantitatively describe lung adenocarcinomas by scoring tumor shape complexity (feature 1: convexity) and intratumor density variation (feature 2: entropy ratio) in routinely obtained diagnostic CT scans. The develop
Externí odkaz:
https://doaj.org/article/13b1772cbf3a4946950996c2a1572661
Autor:
Daniel Verduzco, Mark Lloyd, Liping Xu, Arig Ibrahim-Hashim, Yoganand Balagurunathan, Robert A Gatenby, Robert J Gillies
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120958 (2015)
Hypoxia in tumors correlates with greater risk of metastases, increased invasiveness, and resistance to systemic and radiation therapy. The evolutionary dynamics that links specific adaptations to hypoxia with these observed tumor properties have not
Externí odkaz:
https://doaj.org/article/1ddf4165742f49189bf716c4aea4155b