Zobrazeno 1 - 10
of 411
pro vyhledávání: '"Robert J Fischer"'
Autor:
Neeltje van Doremalen, Trenton Bushmaker, Robert J. Fischer, Atsushi Okumura, Dania M. Figueroa Acosta, Rebekah J. McMinn, Michael Letko, Dana Scott, Greg Saturday, Vincent J. Munster
Publikováno v:
npj Viruses, Vol 2, Iss 1, Pp 1-8 (2024)
Abstract Since 2002, three novel coronavirus outbreaks have occurred: severe acute respiratory syndrome coronavirus (SARS-CoV-1), Middle East respiratory syndrome coronavirus (MERS-CoV), and SARS-CoV-2. A better understanding of the transmission pote
Externí odkaz:
https://doaj.org/article/e7d22fcd180a4218891eaaca9b2cfed1
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 11, Pp 2285-2291 (2023)
Lassa fever, caused by Lassa virus (LASV), is endemic to West Africa, where ≈300,000 illnesses and ≈5,000 deaths occur annually. LASV is primarily spread by infected multimammate rats via urine and fomites, highlighting the need to understand the
Externí odkaz:
https://doaj.org/article/92ff936bc1d4480daff69db36804ea4c
Autor:
Claude Kwe Yinda, Dylan H. Morris, Robert J. Fischer, Shane Gallogly, Zachary A. Weishampel, Julia R. Port, Trenton Bushmaker, Jonathan E. Schulz, Kyle Bibby, Neeltje van Doremalen, James O. Lloyd-Smith, Vincent J. Munster
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 10, Pp 2065-2072 (2023)
An outbreak of human mpox infection in nonendemic countries appears to have been driven largely by transmission through body fluids or skin-to-skin contact during sexual activity. We evaluated the stability of monkeypox virus (MPXV) in different envi
Externí odkaz:
https://doaj.org/article/ee384dabd960462e8b5506cb79a5019e
Autor:
Julia R Port, Dylan H Morris, Jade C Riopelle, Claude Kwe Yinda, Victoria A Avanzato, Myndi G Holbrook, Trenton Bushmaker, Jonathan E Schulz, Taylor A Saturday, Kent Barbian, Colin A Russell, Rose Perry-Gottschalk, Carl Shaia, Craig Martens, James O Lloyd-Smith, Robert J Fischer, Vincent J Munster
Publikováno v:
eLife, Vol 12 (2024)
It remains poorly understood how SARS-CoV-2 infection influences the physiological host factors important for aerosol transmission. We assessed breathing pattern, exhaled droplets, and infectious virus after infection with Alpha and Delta variants of
Externí odkaz:
https://doaj.org/article/4c84307fc85040989316830046220c70
Autor:
Trenton Bushmaker, Claude Kwe Yinda, Dylan H. Morris, Myndi G. Holbrook, Amandine Gamble, Danielle Adney, Cara Bushmaker, Neeltje van Doremalen, Robert J. Fischer, Raina K. Plowright, James O. Lloyd-Smith, Vincent J. Munster
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 5, Pp 1033-1037 (2023)
SARS-CoV-2 transmits principally by air; contact and fomite transmission may also occur. Variants of concern are more transmissible than ancestral SARS-CoV-2. We found indications of possible increased aerosol and surface stability for early variants
Externí odkaz:
https://doaj.org/article/9fcb2fb614f44206a2884be1aeddf5f5
Autor:
Neeltje van Doremalen, Jonathan E. Schulz, Danielle R. Adney, Taylor A. Saturday, Robert J. Fischer, Claude Kwe Yinda, Nazia Thakur, Joseph Newman, Marta Ulaszewska, Sandra Belij-Rammerstorfer, Greg Saturday, Alexandra J. Spencer, Dalan Bailey, Colin A. Russell, Sarah C. Gilbert, Teresa Lambe, Vincent J. Munster
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Whilst the ChAdOx1 nCoV-19 (AZD1222) vaccine has demonstrated efficacy against symptomatic disease, variants of concern (VOCs) with spike protein substitutions have led researchers to explore updating vaccines from ancestral spike protein. Authors us
Externí odkaz:
https://doaj.org/article/31185d37259445658dbebb616238f453
Autor:
Neeltje van Doremalen, Michael Letko, Robert J. Fischer, Trenton Bushmaker, Jonathan Schulz, Claude K. Yinda, Stephanie N. Seifert, Nam Joong Kim, Maged G. Hemida, Ghazi Kayali, Wan Beom Park, Ranawaka A.P.M. Perera, Azaibi Tamin, Natalie J. Thornburg, Suxiang Tong, Krista Queen, Maria D. van Kerkhove, Young Ki Choi, Myoung-don Oh, Abdullah M. Assiri, Malik Peiris, Susan I. Gerber, Vincent J. Munster
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 12, Pp 3052-3062 (2021)
Middle East respiratory syndrome coronavirus (MERS-CoV) infects humans and dromedary camels and is responsible for an ongoing outbreak of severe respiratory illness in humans in the Middle East. Although some mutations found in camel-derived MERS-CoV
Externí odkaz:
https://doaj.org/article/ef527a90ad7d42f4973f658f51a49272
Autor:
Robert J. Fischer, Neeltje van Doremalen, Danielle R. Adney, Claude Kwe Yinda, Julia R. Port, Myndi G. Holbrook, Jonathan E. Schulz, Brandi N. Williamson, Tina Thomas, Kent Barbian, Sarah L. Anzick, Stacy Ricklefs, Brian J. Smith, Dan Long, Craig Martens, Greg Saturday, Emmie de Wit, Sarah C. Gilbert, Teresa Lambe, Vincent J. Munster
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Emerging SARS-CoV-2 variants raise concerns about vaccine effectiveness. Here, the authors show that the ChAdOx1 nCoV-19 (AZD1222) vaccine protects Syrian hamsters from pulmonary infection and disease after infection with SARS-CoV-2 B.1.351 or B.1.1.
Externí odkaz:
https://doaj.org/article/cd521c32186f4059b6298768dcc0d51a
Autor:
Stephanie N Seifert, Robert J Fischer, Eeva Kuisma, Cynthia Badzi Nkoua, Gerard Bounga, Marc-Joël Akongo, Jonathan E Schulz, Beatriz Escudero-Pérez, Beal-Junior Akoundzie, Vishnou Reize Bani Ampiri, Ankara Dieudonne, Ghislain Dzeret Indolo, Serge D Kaba, Igor Louzolo, Lucette Nathalie Macosso, Yanne Mavoungou, Valchy Bel-Bebi Miegakanda, Rock Aimé Nina, Kevin Tolovou Samabide, Alain I Ondzie, Francine Ntoumi, César Muñoz-Fontela, Jean-Vivien Mombouli, Sarah H Olson, Chris Walzer, Fabien Roch Niama, Vincent J Munster
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 6, p e0010504 (2022)
On the 8th of May, 2018, an outbreak of Ebola virus disease (EVD) was declared, originating in the Bikoro region of the Democratic Republic of the Congo (DRC) near the border with neighboring Republic of the Congo (ROC). Frequent trade and migration
Externí odkaz:
https://doaj.org/article/f6fac52858184ab4912b1f275ac026f6
Autor:
Dania M. Figueroa, Eeva Kuisma, M. Jeremiah Matson, Alain U. Ondzie, Trent Bushmaker, Stephanie N. Seifert, Francine Ntoumi, Beatriz Escudero-Pérez, César Muñoz-Fontela, Chris Walzer, Sarah H. Olson, Cynthia Goma-Nkoua, Jean-Vivien Mombouli, Robert J. Fischer, Vincent J. Munster
Publikováno v:
One Health Outlook, Vol 3, Iss 1, Pp 1-6 (2021)
Abstract Early detection of Ebola virus spillover into wildlife is crucial for rapid response. We developed and validated a portable, cold-chain independent Ebola virus RT-qPCR assay. Methods The field syringe-based RNA extraction method was compared
Externí odkaz:
https://doaj.org/article/f40c5b9703424909ba5d7982c44c6e1e