Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Robert J Denver"'
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0287858 (2023)
Amphibian metamorphosis is controlled by thyroid hormone (TH), which binds TH receptors (TRs) to regulate gene expression programs that underlie morphogenesis. Gene expression screens using tissues from premetamorphic tadpoles treated with TH identif
Externí odkaz:
https://doaj.org/article/a9ed806ca6154a59b0d3d597abe9bce5
Autor:
Pia D Bagamasbad, Jose Ezekiel C Espina, Joseph R Knoedler, Arasakumar Subramani, Ariel J Harden, Robert J Denver
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220378 (2019)
The hippocampus is a well-known target of thyroid hormone (TH; e.g., 3,5,3'-triiodothyronine-T3) and glucocorticoid (GC; e.g., corticosterone-CORT) action. Despite evidence that TH and GC play critical roles in neural development and function, few st
Externí odkaz:
https://doaj.org/article/f4b30408d1ff4c958a514543e65d3806
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Complete functional descriptions of the induction sequences of phenotypically plastic traits (perception to physiological regulation to response to outcome) should help us to clarify how plastic responses develop and operate. Ranid tadpoles
Externí odkaz:
https://doaj.org/article/9963937eaab34d6b8a674c8d2eac2821
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Krüppel-like factors (KLFs) are zinc finger transcription factors implicated in diverse biological processes, including differentiation of neural cells. The ability of mammalian neurons to elongate axons decreases during postnatal development in par
Externí odkaz:
https://doaj.org/article/d7f8ae8d7233486db3834e8e0ada9d77
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Genetic accommodation is a potential mechanism for the phenotypic divergence of species. Here, Kulkarni et al. compare endocrine responses of three spadefoot toad species to pond drying and suggest how evolution of mechanisms of developmental plastic
Externí odkaz:
https://doaj.org/article/cdc2037a742a41caba7094715d72a21d
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-22 (2017)
Abstract Background Krüppel-like factor 9 (Klf9) is a zinc finger transcription factor that functions in neural cell differentiation, but little is known about its genomic targets or mechanism of action in neurons. Results We used the mouse hippocam
Externí odkaz:
https://doaj.org/article/edef5a617ec3409981c3eacb9a2b92f8
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Thyroid hormone (T3) plays several key roles in development of the nervous system in vertebrates, controlling diverse processes such as neurogenesis, cell migration, apoptosis, differentiation, and maturation. In anuran amphibians, the hormone exerts
Externí odkaz:
https://doaj.org/article/52f366d318a74fc19dc93202fdb9aa59
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Direct development is a reproductive mode in amphibians that has evolved independently from the ancestral biphasic life history in at least a dozen anuran lineages. Most direct-developing frogs, including the Puerto Rican coquí, Eleutherodactylus co
Externí odkaz:
https://doaj.org/article/7b63cccd0d6b49b4a3249b3cff748d41
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
In addition to its well-known role as an adipostat in adult mammals, leptin has diverse physiological and developmental actions in vertebrates. Leptin has been shown to promote development of hypothalamic circuits and to induce mitosis in different b
Externí odkaz:
https://doaj.org/article/ab8a3c8b7ca54685ae65dfb5b9ea4155
Publikováno v:
Molecular Neurobiology. 57:3785-3802
Kruppel-like factors (KLFs) play key roles in nervous system development and function. Several KLFs are known to promote, and then maintain neural cell differentiation. Our previous work focused on the actions of KLF9 in mouse hippocampal neurons. He