Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Robert J B, Nibbs"'
Autor:
Reshmi Nair, Tamsin R. M. Lannagan, Rene Jackstadt, Anna Andrusaite, John Cole, Caitlin Boyne, Robert J. B. Nibbs, Owen J. Sansom, Simon Milling
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
ABSTRACTColorectal cancer (CRC) is the third most prevalent cancer worldwide with a high mortality rate (20–30%), especially due to metastasis to adjacent organs. Clinical responses to chemotherapy, radiation, targeted and immunotherapies are limit
Externí odkaz:
https://doaj.org/article/990e4b206f444c4f9e950f6acf44d5d0
Autor:
Simone Isling Pærregaard, Line Wulff, Sophie Schussek, Kristoffer Niss, Urs Mörbe, Johan Jendholm, Kerstin Wendland, Anna T. Andrusaite, Kevin F. Brulois, Robert J. B. Nibbs, Katarzyna Sitnik, Allan McI Mowat, Eugene C. Butcher, Søren Brunak, William W. Agace
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The intestinal lamina propria contains a diverse network of fibroblasts that provide key support functions to cells within their local environment. Despite this, our understanding of the diversity, location and ontogeny of fibroblasts within
Externí odkaz:
https://doaj.org/article/87335917aa2d431bbb6623c43b0f8bbc
Autor:
Willy V. Bonneuil, Daniel J. Watson, Jennifer Frattolin, Matthew J. Russell, Francesca Fasanella Masci, Mikaila Bandara, Bindi S. Brook, Robert J. B. Nibbs, James E. Moore Jr.
Publikováno v:
AIP Advances, Vol 12, Iss 2, Pp 025121-025121-14 (2022)
Physiologic chemoattractant gradients are shaped by diffusion, advection, binding to an extracellular matrix, and removal by cells. Previous in vitro tools for studying these gradients and the cellular migratory response have required cells to be con
Externí odkaz:
https://doaj.org/article/b28f91c2c68b4ffda9fd940e5efdd89c
Autor:
Jennifer Frattolin, Daniel J. Watson, Willy V. Bonneuil, Matthew J. Russell, Francesca Fasanella Masci, Mikaila Bandara, Bindi S. Brook, Robert J. B. Nibbs, James E. Moore
Publikováno v:
Cells, Vol 10, Iss 12, p 3439 (2021)
Intravital microscopy and other direct-imaging techniques have allowed for a characterisation of leukocyte migration that has revolutionised the field of immunology, resulting in an unprecedented understanding of the mechanisms of immune response and
Externí odkaz:
https://doaj.org/article/63448ba70e68496cb2a64fb9af9f17c3
Autor:
Heather E. Hulme, Lynsey M. Meikle, Hannah Wessel, Nicole Strittmatter, John Swales, Carolyn Thomson, Anna Nilsson, Robert J. B. Nibbs, Simon Milling, Per E. Andren, C. Logan Mackay, Alex Dexter, Josephine Bunch, Richard J. A. Goodwin, Richard Burchmore, Daniel M. Wall
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Salmonella Typhimurium causes a self-limiting gastroenteritis that may lead to systemic disease. Bacteria invade the small intestine, crossing the intestinal epithelium from where they are transported to the mesenteric lymph nodes (MLNs) wit
Externí odkaz:
https://doaj.org/article/3a24c8a8c4bd40bd88a9c66a0de21e92
Autor:
Albert Zlotnik, Osamu Yoshie, Mohib Uddin, Marcus Thelen, Alexander H. Sparre-Ulrich, Silvano Sozzani, Antal Rot, Mette M. Rosenkilde, Amanda E. I. Proudfoot, Christine A. Power, Joost J. Oppenheim, Hisayuki Nomiyama, Robert J. B. Nibbs, Philip M. Murphy, Georgios L. Moschovakis, Amy E. Monaghan, Kouji Matsushima, Alberto Mantovani, Andrew D. Luster, Massimo Locati, Richard Horuk, Rebecca Hills, Gerard J. Graham, Joshua M. Farber, Reinhold Förster, Christophe Combadiere, Israel F. Charo, Amanda M. Burkhardt, Adit Ben-Baruch, Francoise Bachelerie
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Chemokine receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Chemokine Receptors [438, 437, 32]) comprise a large subfamily of 7TM proteins that bind one or more chemokines, a large family of small cytokines typically possessing chemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdabff92dd3a87ec119470747102cddc
https://doi.org/10.2218/gtopdb/f14/2023.1
https://doi.org/10.2218/gtopdb/f14/2023.1
Autor:
Simone Isling Pærregaard, Line Wulff, Sophie Schussek, Kristoffer Niss, Urs Mörbe, Johan Jendholm, Kerstin Wendland, Anna T. Andrusaite, Kevin F. Brulois, Robert J. B. Nibbs, Katarzyna Sitnik, Allan McI Mowat, Eugene C. Butcher, Søren Brunak, William W. Agace
Publikováno v:
Nature Communications. 14
The intestinal lamina propria contains a diverse network of fibroblasts that provide key support functions to cells within their local environment. Despite this, our understanding of the diversity, location and ontogeny of fibroblasts within and alon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a48ba203dc33fb63c63c73e3546807ab
https://doi.org/10.1038/s41467-023-37952-5
https://doi.org/10.1038/s41467-023-37952-5
Autor:
Katarzyna M. Sitnik, S. I. Paerregaard, Kerstin Wendland, Johan Jendholm, U. Moerbe, Robert J. B. Nibbs, Kevin Brulois, Eugene C. Butcher, L. Wulff, Anna Andrusaite, William W. Agace, Søren Brunak, Kristoffer Niss, S. Schussek, Allan McI. Mowat
SummaryIntestinal fibroblasts (FB) play essential roles in intestinal homeostasis. Here we show that the small and large intestinal lamina propria (LP) contain similar FB subsets that locate in specific anatomical niches and express distinct arrays o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53f95821e56e3c5f19667eb7522dfba9
https://doi.org/10.1101/2021.08.13.456086
https://doi.org/10.1101/2021.08.13.456086
Publikováno v:
Immunological Investigations. 49:264-286
Homeostatic leukocyte trafficking into and within the female reproductive tract (FRT) contributes to fertility and reproductive health. It is unclear how this process is regulated in the anatomically distinct reproductive tissues, or whether the gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95e9609214ea0b143931f2fd63e2273
https://doi.org/10.1080/08820139.2019.1655573
https://doi.org/10.1080/08820139.2019.1655573
Publikováno v:
Cells, Vol 5, Iss 2, p 14 (2016)
Bcl-3 is a member of the IκB family of proteins and an important regulator of Nuclear Factor (NF)-κB activity. The ability of Bcl-3 to bind and regulate specific NF-κB dimers has been studied in great depth, but its physiological roles in vivo are
Externí odkaz:
https://doaj.org/article/b61d255e2c29436d882b6e5ad2c1fb1e