Zobrazeno 1 - 10
of 1 194
pro vyhledávání: '"Robert J, Young"'
Autor:
A. Lina Heinzke, Barbara Zdrazil, Paul D. Leeson, Robert J. Young, Axel Pahl, Herbert Waldmann, Andrew R. Leach
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-9 (2024)
Abstract Providing a better understanding of what makes a compound a successful drug candidate is crucial for reducing the high attrition rates in drug discovery. Analyses of the differences between active compounds, clinical candidates and drugs req
Externí odkaz:
https://doaj.org/article/6b7b2abb2a09429392f3cc739a7e6c8c
Autor:
Luis Filipe de Souza Godoy, Vitor Ribeiro Paes, Aline Sgnolf Ayres, Gabriela Alencar Bandeira, Raquel Andrade Moreno, Fabiana de Campos Cordeiro Hirata, Frederico Adolfo Benevides Silva, Felipe Nascimento, Guilherme de Carvalho Campos Neto, Andre Felix Gentil, Leandro Tavares Lucato, Edson Amaro Junior, Robert J. Young, Suzana Maria Fleury Malheiros
Publikováno v:
Arquivos de Neuro-Psiquiatria, Vol 81, Iss 12, Pp 1134-1145 (2023)
In recent decades, there have been significant advances in the diagnosis of diffuse gliomas, driven by the integration of novel technologies. These advancements have deepened our understanding of tumor oncogenesis, enabling a more refined stratificat
Externí odkaz:
https://doaj.org/article/3ec32aff32bd475c863dea990727ea6d
Autor:
Brandon S. Imber, MD, MA, Ryka Sehgal, MD, Rachel Saganty, MD, Anne S. Reiner, MPH, A. Turan Ilica, MD, Emily Miao, PharmD, Bob T. Li, MD, Gregory J. Riely, MD, Helena A. Yu, MD, Katherine S. Panageas, DrPH, Robert J. Young, MD, Luke R.G. Pike, MD, DPhil, Nelson S. Moss, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 12, Pp 100607- (2023)
Introduction: Patients with EGFR-mutant NSCLC have a high incidence of brain metastases. The EGFR-directed tyrosine kinase inhibitor osimertinib has intracranial activity, making the role of local central nervous system (CNS)-directed therapies, such
Externí odkaz:
https://doaj.org/article/eb50687c81bc4fa09768c4beb4a3d785
Autor:
Matthew J. Fong, Christopher S. Woodhead, Nema M. Abdelazim, Daniel C. Abreu, Angelo Lamantia, Elliott M. Ball, Kieran Longmate, David Howarth, Benjamin J. Robinson, Phillip Speed, Robert J. Young
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Unique identification of optical devices is important for anti-counterfeiting. Physical unclonable functions (PUFs), which use random physical characteristics for authentication, are advantageous over existing optical solutions, such as holo
Externí odkaz:
https://doaj.org/article/caf198f4a0614c57aa21249c6e511a59
Autor:
David B. Page, Kathryn Beal, Stefanie N. Linch, Kateri J. Spinelli, Micaela Rodine, Darragh Halpenny, Shanu Modi, Sujata Patil, Robert J. Young, Thomas Kaley, Taha Merghoub, David Redmond, Phillip Wong, Christopher A. Barker, Adi Diab, Larry Norton, Heather L. McArthur
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract Breast cancer brain metastases (BCBM) are a common and devastating complication of metastatic breast cancer with conventional systemic therapies demonstrating limited effectiveness. Consequently, radiotherapy (RT) ± surgery remains the corn
Externí odkaz:
https://doaj.org/article/c76ecfb18ed24f4fb871ae3e8b25cbd9
Autor:
Yameng Cao, Sebastian Wood, Filipe Richheimer, J. Blakesley, Robert J. Young, Fernando A. Castro
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Controlling the radiative properties of monolayer transition metal dichalcogenides is key to the development of atomically thin optoelectronic devices applicable to a wide range of industries. A common problem for exfoliated materials is the
Externí odkaz:
https://doaj.org/article/83f7bb271d684648ad1455d1f94befe9
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Quantum dot physically unclonable functions (QD-PUFs) provide a promising solution to the issue of counterfeiting. When quantum dots are deposited on a surface to create a token, they form a unique pattern that is unlikely to ever be reprodu
Externí odkaz:
https://doaj.org/article/96d75cfb503340488d7ed98a1a1546fa
Autor:
Nema M. Abdelazim, Matthew J. Fong, Thomas McGrath, Christopher S. Woodhead, Furat Al-Saymari, Ibrahim E. Bagci, Alex T. Jones, Xintai Wang, Robert J. Young
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Nanoscale variations in the structure and composition of an object are an enticing basis for verifying its identity, due to the physical complexity of attempting to reproduce such a system. The biggest practical challenge for nanoscale authe
Externí odkaz:
https://doaj.org/article/29e0b687890f44f3b3691451d17b759b
Autor:
Jung Woo Leem, Min Seok Kim, Seung Ho Choi, Seong-Ryul Kim, Seong-Wan Kim, Young Min Song, Robert J. Young, Young L. Kim
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Counterfeit medicines are a threat to patient health and public safety. Here, the authors use random patterns formed by fluorescent silk microparticles with various excitation and emission pairs as an edible physical unclonable function that can dire
Externí odkaz:
https://doaj.org/article/baaf3061732446a8abe01557c89382b0
Autor:
Omar M. Dawood, Rakesh Kumar Gupta, Umberto Monteverde, Faisal H. Alqahtani, Hong-Yeol Kim, James Sexton, Robert J. Young, Mohamed Missous, Max A. Migliorato
Publikováno v:
Science and Technology of Advanced Materials, Vol 20, Iss 1, Pp 568-579 (2019)
Freestanding (suspended) graphene films, with high electron mobility (up to ~200,000 cm2V−1s−1), good mechanical and electronic properties, could resolve many of the current issues that are hampering the upscaling of graphene technology. Thus far
Externí odkaz:
https://doaj.org/article/32004c7894894726bf397444a6f1baaf