Zobrazeno 1 - 10
of 526
pro vyhledávání: '"Robert J, Williams"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-15 (2024)
Abstract Tauopathies are characterised by the pathological accumulation of misfolded tau. The emerging view is that toxic tau species drive synaptic dysfunction and potentially tau propagation before measurable neurodegeneration is evident, but the u
Externí odkaz:
https://doaj.org/article/b84b2ce52d414462b8e67e2f70fbe8f0
Autor:
John C. Dawson, Alison Munro, Kenneth Macleod, Morwenna Muir, Paul Timpson, Robert J. Williams, Margaret Frame, Valerie G. Brunton, Neil O. Carragher
Publikováno v:
Molecular Oncology, Vol 16, Iss 5, Pp 1072-1090 (2022)
A more comprehensive understanding of how cells respond to drug intervention, the likely immediate signalling responses and how resistance may develop within different microenvironments will help inform treatment regimes. The nonreceptor tyrosine kin
Externí odkaz:
https://doaj.org/article/fab8f61f00ef4132b7b597f9dca6a022
Autor:
David C. Hodgins, Robert J. Williams, Yale D. Belanger, Darren R. Christensen, Nady El-Guebaly, Daniel S. McGrath, Fiona Nicoll, Carrie A. Shaw, Rhys M. G. Stevens
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
ObjectiveThis study examined past year attempts to reduce or quit gambling among people who gamble generally and those with gambling problems specifically.MethodsRegular gamblers recruited from an online panel (N = 10,054) completed a survey of gambl
Externí odkaz:
https://doaj.org/article/b583c9c28e5e469cb50cd6e5b9d94388
Autor:
Ioanna Pavlaki, Michael Shapiro, Giuseppina Pisignano, Stephanie M E Jones, Jelena Telenius, Silvia Muñoz-Descalzo, Robert J Williams, Jim R Hughes, Keith W Vance
Publikováno v:
PLoS Genetics, Vol 18, Iss 6, p e1010230 (2022)
Central nervous system-expressed long non-coding RNAs (lncRNAs) are often located in the genome close to protein coding genes involved in transcriptional control. Such lncRNA-protein coding gene pairs are frequently temporally and spatially co-expres
Externí odkaz:
https://doaj.org/article/267aa164ac8d4000b31b4e3e36f9ad6c
Publikováno v:
Ecology and Evolution, Vol 11, Iss 7, Pp 3332-3346 (2021)
Abstract Invasive species are one of the main causes of biodiversity loss worldwide. As introduced, populations increase in abundance and geographical range, so does the potential for negative impacts on native communities. As such, there is a need t
Externí odkaz:
https://doaj.org/article/de81d35e28ee48508b71e0e0560d0175
Publikováno v:
BMC Psychiatry, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background There is little longitudinal evidence on the cumulative risk of harm from gambling associated with excess spending and frequency of play. The present study sought to assess the risk of gambling problems over a five-year period in
Externí odkaz:
https://doaj.org/article/5bf3fcab2c2b4d3abcf053d0a996845d
Publikováno v:
Frontiers in Psychology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/8fb380253b4c456d9b2f2de53dac6b81
Autor:
Katriona L. Hole, Lydia E. Staniaszek, Gayathri Menon Balan, Jody M. Mason, Jon T. Brown, Robert J. Williams
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Aggregation of the microtubule-associated protein tau into paired helical filaments (PHFs) and neurofibrillary tangles is a defining characteristic of Alzheimer’s Disease. Various plant polyphenols disrupt tau aggregation in vitro but display poor
Externí odkaz:
https://doaj.org/article/7c25e2f2c9814601ab0b951a342a7015
Autor:
Robert J, Williams, Carrie A, Shaw, Yale D, Belanger, Darren R, Christensen, Nady, El-Guebaly, David C, Hodgins, Daniel S, McGrath, Rhys M G, Stevens
Publikováno v:
Psychology of Addictive Behaviors. 37:483-498
To conduct a large-scale national cohort study to identify the current etiological risk factors for problem gambling in Canada.A cohort of 10,119 Canadian gamblers completed a comprehensive self-administered online questionnaire in 2018 and were reas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c90e6d585492c081838d3c60fe45128
https://doi.org/10.1037/adb0000843
https://doi.org/10.1037/adb0000843
Publikováno v:
Canadian Journal of Addiction. 14:26-34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71ed69ecc26ace6896f7334cd84265d6
https://doi.org/10.1097/cxa.0000000000000171
https://doi.org/10.1097/cxa.0000000000000171