Zobrazeno 1 - 10
of 469
pro vyhledávání: '"Robert J, Unwin"'
Autor:
Gemma Harris, Michelle L. Bradshaw, David J. Halsall, David J. Scott, Robert J. Unwin, Anthony G. W. Norden
Publikováno v:
Experimental Physiology, Vol 109, Iss 10, Pp 1663-1671 (2024)
Abstract Most albumin in blood plasma is thought to be monomeric with some 5% covalently dimerized. However, many reports in the recent biophysics literature find that albumin is reversibly dimerized or even oligomerized. We review data on this from
Externí odkaz:
https://doaj.org/article/69c035f2edd54303a8d42d6f53249e13
Autor:
Letizia Zeni, Anthony G. W. Norden, Elena Prandi, Carolina Canepa, Keith Burling, Katherine Simpson, Barbara Felappi, Alessandro Plebani, Giovanni Cancarini, Pietro Manuel Ferraro, Donald Fraser, Robert J. Unwin
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 14, Iss 1, Pp 1-10 (2022)
Abstract Background The pathogenesis of diabetic kidney disease (DKD) is complex and involves both glomerular and tubular dysfunction. A global assessment of kidney function is necessary to stage DKD, a progressive kidney disease that is likely to be
Externí odkaz:
https://doaj.org/article/3cb000af96d94a0ba676f8e082524a31
Autor:
Robert J. Unwin
Publikováno v:
Kidney & Blood Pressure Research, Vol 46, Iss 5, Pp 639-646 (2021)
Background: It is just over a century since the 1918 flu pandemic, sometimes referred to as the “mother” of pandemics. This brief retrospective of the 1918 pandemic is taken from the viewpoint of the current SARS-CoV-2/COVID-19 pandemic and is ba
Externí odkaz:
https://doaj.org/article/67ea5541facc412cb8bbd3bc0517bb8f
Autor:
Timo N. Haschler, Harry Horsley, Monika Balys, Glenn Anderson, Jan-Willem Taanman, Robert J. Unwin, Jill T. Norman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Ischemia is a major cause of kidney damage. Proximal tubular epithelial cells (PTECs) are highly susceptible to ischemic insults that frequently cause acute kidney injury (AKI), a potentially life-threatening condition with high mortality. A
Externí odkaz:
https://doaj.org/article/bf7c614184604ba8a7792b2421c0cbc7
Autor:
Pierre Bissonnette, Yoann Lussier, Jessica Matar, Alexandre Leduc‐Nadeau, Sandra Da Cal, Marie‐Françoise Arthus, Robert J. Unwin, Julia Steinke, Dharshan Rangaswamy, Daniel G. Bichet
Publikováno v:
Physiological Reports, Vol 9, Iss 11, Pp n/a-n/a (2021)
Abstract Aquaporin‐2 (AQP2) is a homotetrameric water channel responsible for the final water reuptake in the kidney. Disease‐causing AQP2 mutations induce nephrogenic diabetes insipidus (NDI), a condition that challenges the bodily water balance
Externí odkaz:
https://doaj.org/article/aa0c019621244c8c983c7ae83b1bb46e
Autor:
Robert I. Menzies, John W.R. Booth, John J. Mullins, Matthew A. Bailey, Frederick W.K. Tam, Jill T. Norman, Robert J. Unwin
Publikováno v:
EBioMedicine, Vol 19, Iss C, Pp 73-83 (2017)
Diabetes is a leading cause of renal disease. Glomerular mesangial expansion and fibrosis are hallmarks of diabetic nephropathy and this is thought to be promoted by infiltration of circulating macrophages. Monocyte chemoattractant protein-1 (MCP-1)
Externí odkaz:
https://doaj.org/article/09543f448dd741b5bce76b3c6f64b596
Publikováno v:
Kidney360
Stages of CKD are currently defined by eGFR and require measurement of serum creatinine concentrations. Previous studies have shown a good correlation between salivary and serum urea levels and the stage of CKD. However, quantitative salivary urea as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8cce0ee2268316d657a88de4dd2607
https://doi.org/10.34067/kid.0004362021
https://doi.org/10.34067/kid.0004362021
Autor:
Giovambattista Capasso, Francesco Trepiccione, Gaye Hafez, Ewout J. Hoorn, Robert J. Unwin, Denis Fouque, Alberto Ortiz, Chris I. De Zeeuw, Rikke Nielsen, Vesna Pešić, Pedro Henrique Imenez Silva, Carsten A. Wagner, Ziad A. Massy
Publikováno v:
Nephrology Dialysis Transplantation
Imenez Silva, Pedro H; Unwin, Robert; Hoorn, Ewout J; Ortiz, Alberto; Trepiccione, Francesco; Nielsen, Rikke; Pesic, Vesna; Hafez, Gaye; Fouque, Denis; Massy, Ziad A; De Zeeuw, Chris I; Capasso, Giovambattista; Wagner, Carsten A (2021). Acidosis, cognitive dysfunction and motor impairments in patients with kidney disease. Nephrology, dialysis, transplantation, 37(Supplement_2), ii4-ii12. Oxford University Press 10.1093/ndt/gfab216
Nephrology Dialysis Transplantation, 37(2), ii4-ii12. Oxford University Press
Nephrology Dialysis Transplantation, 37(supplement 2), ii4-ii12. Oxford University Press
Imenez Silva, P H, Unwin, R, Hoorn, E J, Ortiz, A, Trepiccione, F, Nielsen, R, Pesic, V, Hafez, G, Fouque, D, Massy, Z A, De Zeeuw, C I, Capasso, G, Wagner, C A & CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) 2022, ' Acidosis, cognitive dysfunction and motor impairments in patients with kidney disease ', Nephrology Dialysis Transplantation, vol. 37, no. Supplement 2, pp. ii4-ii12 . https://doi.org/10.1093/ndt/gfab216
Imenez Silva, Pedro H; Unwin, Robert; Hoorn, Ewout J; Ortiz, Alberto; Trepiccione, Francesco; Nielsen, Rikke; Pesic, Vesna; Hafez, Gaye; Fouque, Denis; Massy, Ziad A; De Zeeuw, Chris I; Capasso, Giovambattista; Wagner, Carsten A (2021). Acidosis, cognitive dysfunction and motor impairments in patients with kidney disease. Nephrology, dialysis, transplantation, 37(Supplement_2), ii4-ii12. Oxford University Press 10.1093/ndt/gfab216
Nephrology Dialysis Transplantation, 37(2), ii4-ii12. Oxford University Press
Nephrology Dialysis Transplantation, 37(supplement 2), ii4-ii12. Oxford University Press
Imenez Silva, P H, Unwin, R, Hoorn, E J, Ortiz, A, Trepiccione, F, Nielsen, R, Pesic, V, Hafez, G, Fouque, D, Massy, Z A, De Zeeuw, C I, Capasso, G, Wagner, C A & CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target) 2022, ' Acidosis, cognitive dysfunction and motor impairments in patients with kidney disease ', Nephrology Dialysis Transplantation, vol. 37, no. Supplement 2, pp. ii4-ii12 . https://doi.org/10.1093/ndt/gfab216
Metabolic acidosis, defined as a plasma or serum bicarbonate concentration
Graphical Abstract Graphical Abstract
Graphical Abstract Graphical Abstract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d94e2eb2e3e25fa19e123adab4eb667
https://hdl.handle.net/20.500.11755/1a067470-b626-4ff1-bbb6-72f93c5b3f38
https://hdl.handle.net/20.500.11755/1a067470-b626-4ff1-bbb6-72f93c5b3f38
Autor:
William G. Robertson, Gianmarco Lombardi, Robert J Unwin, Giovanni Gambaro, Shabbir Moochhala, Matteo Bargagli, Pietro Manuel Ferraro
Publikováno v:
Journal of Nephrology. 35:851-857
Objective Kidney stone disease seems to be associated with an increased risk of incident cardiovascular outcomes; the aim of this study is to identify differences in 24-h urine excretory profiles and stone composition among stone formers with and wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664b9a2cfab686fb170d2092550e7960
https://doi.org/10.1007/s40620-021-01096-w
https://doi.org/10.1007/s40620-021-01096-w
Autor:
Joanne, Marks, Robert J, Unwin
Publikováno v:
Vitamins and hormones. 120
Phosphate homeostasis is dependent on the interaction and coordination of four main organ systems: thyroid/parathyroids, gastrointestinal tract, bone and kidneys, and three key hormonal regulators, 1,25-hydroxyvitamin D3, parathyroid hormone and FGF2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f05ed615a04ae1781f65dac19f43df6
https://pubmed.ncbi.nlm.nih.gov/35953117
https://pubmed.ncbi.nlm.nih.gov/35953117