Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Robert J, Tower"'
Autor:
Yiyun Wang, Qizhi Qin, Ziyi Wang, Stefano Negri, Takashi Sono, Robert J. Tower, Zhao Li, Xin Xing, Mary Archer, Neelima Thottappillil, Manyu Zhu, Allister Suarez, Deok-Ho Kim, Tyler Harvey, Chen-Ming Fan, Aaron W. James
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-15 (2024)
Abstract The regeneration of the mammalian skeleton’s craniofacial bones necessitates the action of intrinsic and extrinsic inductive factors from multiple cell types, which function hierarchically and temporally to control the differentiation of o
Externí odkaz:
https://doaj.org/article/5800b8472f1d49b1972a215f61072512
Autor:
Heeseog Kang, Amy L. Strong, Yuxiao Sun, Lei Guo, Conan Juan, Alec C. Bancroft, Ji Hae Choi, Chase A. Pagani, Aysel A. Fernandes, Michael Woodard, Juhoon Lee, Sowmya Ramesh, Aaron W. James, David Hudson, Kevin N. Dalby, Lin Xu, Robert J. Tower, Benjamin Levi
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-13 (2024)
Abstract While hypoxic signaling has been shown to play a role in many cellular processes, its role in metabolism-linked extracellular matrix (ECM) organization and downstream processes of cell fate after musculoskeletal injury remains to be determin
Externí odkaz:
https://doaj.org/article/bbe26278c92c4c7694b18c1d110b314f
Autor:
Xue Xiao, Conan Juan, Tingsheng Drennon, Cedric R. Uytingco, Neda Vishlaghi, Dimitri Sokolowskei, Lin Xu, Benjamin Levi, Mimi C. Sammarco, Robert J. Tower
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-13 (2023)
Abstract Self-renewal and differentiation of skeletal stem and progenitor cells (SSPCs) are tightly regulated processes, with SSPC dysregulation leading to progressive bone disease. While the application of single-cell RNA sequencing (scRNAseq) to th
Externí odkaz:
https://doaj.org/article/139c56a9dedf4675ba5ce8807176a3d4
Autor:
Neda Vishlaghi, Lei Guo, Danielle Griswold-Wheeler, Yuxiao Sun, Cori Booker, Janna L. Crossley, Alec C. Bancroft, Conan Juan, Sneha Korlakunta, Sowmya Ramesh, Chase A. Pagani, Lin Xu, Aaron W. James, Robert J. Tower, Michael Dellinger, Benjamin Levi
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114049- (2024)
Summary: Heterotopic ossification (HO) is a challenging condition that occurs after musculoskeletal injury and is characterized by the formation of bone in non-skeletal tissues. While the effect of HO on blood vessels is well established, little is k
Externí odkaz:
https://doaj.org/article/380f2e9c21d64906ac902f08059b24b6
Autor:
Janna L. Crossley, Sonya Ostashevskaya-Gohstand, Stefano Comazzetto, Jessica S. Hook, Lei Guo, Neda Vishlaghi, Conan Juan, Lin Xu, Alexander R. Horswill, Gerta Hoxhaj, Jessica G. Moreland, Robert J. Tower, Benjamin Levi
Publikováno v:
JCI Insight, Vol 8, Iss 20 (2023)
Modulation of the immune response to initiate and halt the inflammatory process occurs both at the site of injury as well as systemically. Due to the evolving role of cellular metabolism in regulating cell fate and function, tendon injuries that unde
Externí odkaz:
https://doaj.org/article/de41bdacaa51470f9d19876b0d0fa043
Autor:
Qizhi Qin, Mario Gomez-Salazar, Masnsen Cherief, Chase A. Pagani, Seungyong Lee, Charles Hwang, Robert J. Tower, Sharon Onggo, Yuxiao Sun, Abhinav Piplani, Zhao Li, Sowmya Ramesh, Thomas L. Clemens, Benjamin Levi, Aaron W. James
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-12 (2022)
Abstract The functional interdependence of nerves and blood vessels is a well-established concept during tissue morphogenesis, yet the role of neurovascular coupling in proper and aberrant tissue repair is an emerging field of interest. Here, we soug
Externí odkaz:
https://doaj.org/article/ef7282b1693d42e9be9a1347385481ec
Autor:
Chase A. Pagani, BA, Alec C. Bancroft, BS, Robert J. Tower, PhD, Nicholas Livingston, BS, Yuxiao Sun, PhD, Johnathan Y. Hong, BS, Benjamin A. Nanes, PhD, Robert N. Kent, BS, Kevin Dean, PhD, Renny Franceschi, PhD, Brendon M. Baker, PhD, Stephen J. Weiss, PhD, Benjamin Levi, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 11, Iss 5S, Pp 7-8 (2023)
Externí odkaz:
https://doaj.org/article/95ca1698faf34ab79e60c475135eb7ae
Autor:
Jiajia Xu, Yiyun Wang, Zhu Li, Ye Tian, Zhao Li, Amy Lu, Ching-Yun Hsu, Stefano Negri, Cammy Tang, Robert J. Tower, Carol Morris, Aaron W. James
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-15 (2022)
Abstract The outer coverings of the skeleton, which is also known as the periosteum, are arranged in concentric layers and act as a reservoir for tissue-specific bone progenitors. The cellular heterogeneity within this tissue depot is being increasin
Externí odkaz:
https://doaj.org/article/288858cb59cb434d84de9ff06d11d1b3
Autor:
Seungyong Lee, Charles Hwang, Simone Marini, Robert J. Tower, Qizhi Qin, Stefano Negri, Chase A. Pagani, Yuxiao Sun, David M. Stepien, Michael Sorkin, Carrie A. Kubiak, Noelle D. Visser, Carolyn A. Meyers, Yiyun Wang, Husain A. Rasheed, Jiajia Xu, Sarah Miller, Amanda K. Huber, Liliana Minichiello, Paul S. Cederna, Stephen W. P. Kemp, Thomas L. Clemens, Aaron W. James, Benjamin Levi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Soft tissue trauma can result in aberrant osteochondral differentiation of local mesenchymal progenitor cells. Here the authors show that, in mice, soft tissue trauma results in NGF expression by perivascular cells, which leads to axonal invasion and
Externí odkaz:
https://doaj.org/article/8294374ecf224a3ea40a708dc54a22e2
Autor:
Robert J Tower, Emily Busse, Josue Jaramillo, Michelle Lacey, Kevin Hoffseth, Anyonya R Guntur, Jennifer Simkin, Mimi C Sammarco
Publikováno v:
eLife, Vol 11 (2022)
De novo limb regeneration after amputation is restricted in mammals to the distal digit tip. Central to this regenerative process is the blastema, a heterogeneous population of lineage-restricted, dedifferentiated cells that ultimately orchestrates r
Externí odkaz:
https://doaj.org/article/2a598576685044ffb8c6917409c773c1