Zobrazeno 1 - 10
of 807
pro vyhledávání: '"Robert J, Soiffer"'
Autor:
Livius Penter, Mehdi Borji, Adi Nagler, Haoxiang Lyu, Wesley S. Lu, Nicoletta Cieri, Katie Maurer, Giacomo Oliveira, Aziz M. Al’Khafaji, Kiran V. Garimella, Shuqiang Li, Donna S. Neuberg, Jerome Ritz, Robert J. Soiffer, Jacqueline S. Garcia, Kenneth J. Livak, Catherine J. Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Single-cell transcriptomics has become the definitive method for classifying cell types and states, and can be augmented with genotype information to improve cell lineage identification. Due to constraints of short-read sequencing, current m
Externí odkaz:
https://doaj.org/article/db7bcebda28b4a739047f63c97488177
Autor:
Pavan Bachireddy, Elham Azizi, Cassandra Burdziak, Vinhkhang N. Nguyen, Christina S. Ennis, Katie Maurer, Cameron Y. Park, Zi-Ning Choo, Shuqiang Li, Satyen H. Gohil, Neil G. Ruthen, Zhongqi Ge, Derin B. Keskin, Nicoletta Cieri, Kenneth J. Livak, Haesook T. Kim, Donna S. Neuberg, Robert J. Soiffer, Jerome Ritz, Edwin P. Alyea, Dana Pe’er, Catherine J. Wu
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 113011- (2023)
Externí odkaz:
https://doaj.org/article/c8c0c331d71e45789e2a6e510d78fc48
Autor:
Joanna Zurko, Jeremy Ramdial, Mazyar Shadman, Sairah Ahmed, Aniko Szabo, Lorenzo Iovino, Ana Alarcon Tomas, Craig Sauter, Miguel-Angel Perales, Nirav. N. Shah, Utkarsh H. Acharya, Caron Jacobson, Robert J. Soiffer, Trent Wang, Krishna V. Komanduri, Samantha Jaglowski, Adam S. Kittai, Nathan Denlinger, Madiha Iqbal, Mohamed A. Kharfan-Dabaja, Ernesto Ayala, Julio Chavez, Michael Jain, Frederick L. Locke, Yazeed Samara, Lihua E. Budde, Matthew G. Mei, Alexandra Della Pia, Tatyana Feldman, Nausheen Ahmed, Ryan Jacobs, Nilanjan Ghosh, Bhagirathbhai Dholaria, Olalekan O. Oluwole, Brian Hess, Ayesha Hassan, Vaishalee P. Kenkre, Patrick Reagan, Farrukh Awan, Yago Nieto, Mehdi Hamadani, Alex F. Herrera
Publikováno v:
Haematologica, Vol 108, Iss 1 (2022)
Allogeneic hematopoietic cell transplantation (alloHCT) can potentially salvage large B-cell lymphoma (LBCL) patients experiencing treatment failure after chimeric antigen receptor T-cell therapy (CAR T). Nonetheless, data on the efficacy and toxicit
Externí odkaz:
https://doaj.org/article/79e2386110cd4911812ba846c2081e54
Autor:
Roman M. Shapiro, Grace C. Birch, Guangan Hu, Juliana Vergara Cadavid, Sarah Nikiforow, Joanna Baginska, Alaa K. Ali, Mubin Tarannum, Michal Sheffer, Yasmin Z. Abdulhamid, Benedetta Rambaldi, Yohei Arihara, Carol Reynolds, Max S. Halpern, Scott J. Rodig, Nicole Cullen, Jacquelyn O. Wolff, Kathleen L. Pfaff, Andrew A. Lane, R. Coleman Lindsley, Corey S. Cutler, Joseph H. Antin, Vincent T. Ho, John Koreth, Mahasweta Gooptu, Haesook T. Kim, Karl-Johan Malmberg, Catherine J. Wu, Jianzhu Chen, Robert J. Soiffer, Jerome Ritz, Rizwan Romee
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 11 (2022)
Background Responses to conventional donor lymphocyte infusion for postallogeneic hematopoietic cell transplantation (HCT) relapse are typically poor. Natural killer (NK) cell–based therapy is a promising modality to treat post-HCT relapse.Methods
Externí odkaz:
https://doaj.org/article/2699fa01730746f2b44f722f69c72b21
Autor:
Tarek H. Mouhieddine, Adam S. Sperling, Robert Redd, Jihye Park, Matthew Leventhal, Christopher J. Gibson, Salomon Manier, Amin H. Nassar, Marzia Capelletti, Daisy Huynh, Mark Bustoros, Romanos Sklavenitis-Pistofidis, Sabrin Tahri, Kalvis Hornburg, Henry Dumke, Muhieddine M. Itani, Cody J. Boehner, Chia-Jen Liu, Saud H. AlDubayan, Brendan Reardon, Eliezer M. Van Allen, Jonathan J. Keats, Chip Stewart, Shaadi Mehr, Daniel Auclair, Robert L. Schlossman, Nikhil C. Munshi, Kenneth C. Anderson, David P. Steensma, Jacob P. Laubach, Paul G. Richardson, Jerome Ritz, Benjamin L. Ebert, Robert J. Soiffer, Lorenzo Trippa, Gad Getz, Donna S. Neuberg, Irene M. Ghobrial
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Multiple myeloma (MM) is treated with induction chemotherapy, autologous stem cell transplant (ASCT) and long-term immunomodulatory drug (IMiD) maintenance. Here, the authors show that the presence of clonal haematopoiesis of indeterminate potential
Externí odkaz:
https://doaj.org/article/26a4f18ed00849e6bce820eacad6b32d
Autor:
Benedetta Rambaldi, Haesook T. Kim, Yohei Arihara, Takeru Asano, Carol Reynolds, Mariah Manter, Max Halpern, Augustine Weber, John Koreth, Corey Cutler, Mahasweta Gooptu, Sarah Nikiforow, Vincent T. Ho, Joseph H. Antin, Rizwan Romee, Jeanette Ampudia, Cherie Ng, Stephen Connelly, Robert J. Soiffer, Jerome Ritz
Publikováno v:
Haematologica, Vol 107, Iss 11 (2022)
CD6 is a co-stimulatory receptor expressed on T cells that binds activated leukocyte cell adhesion molecule (ALCAM), expressed on antigen presenting cells, epithelial and endothelial tissues. The CD6-ALCAM pathway plays an integral role in modulating
Externí odkaz:
https://doaj.org/article/028cbeb056154b0f986dae1e00d73c08
Autor:
Clark DuMontier, Hajime Uno, Tammy Hshieh, Guohai Zhou, Richard Chen, Emily S. Magnavita, Lee Mozessohn, Houman Javedan, Richard M. Stone, Robert J. Soiffer, Jane A. Driver, Gregory A. Abel
Publikováno v:
Haematologica, Vol 107, Iss 5 (2021)
We conducted a randomized controlled trial in older adults with hematologic malignancies to determine the impact of geriatrician consultation embedded in our oncology clinic alongside standard care. From February 2015 to May 2018, transplant-ineligib
Externí odkaz:
https://doaj.org/article/02c5de83eb3f4ce0af2f4a20bf6a1e9c
Autor:
Haesook T. Kim, Peter O. Baker, Erin Parry, Matthew Davids, Edwin P. Alyea, Vincent T. Ho, Corey Cutler, John Koreth, Mahasweta Gooptu, Rizwan Romee, Sarah Nikiforow, Joseph H. Antin, Jerome Ritz, Robert J. Soiffer, Catherine J. Wu, Jennifer R. Brown
Publikováno v:
Haematologica, Vol 106, Iss 12 (2021)
Externí odkaz:
https://doaj.org/article/7dd653f984984ac8967ac5f65f2ffb3c
Autor:
Jennifer S. Whangbo, Haesook T. Kim, Nikola Mirkovic, Lauren Leonard, Samuel Poryanda, Sophie Silverstein, Soomin Kim, Carol G. Reynolds, Sharmila C. Rai, Kelly Verrill, Michelle A. Lee, Steven Margossian, Christine Duncan, Leslie Lehmann, Jennifer Huang, Sarah Nikiforow, Edwin P. Alyea, III, Philippe Armand, Corey S. Cutler, Vincent T. Ho, Bruce R. Blazar, Joseph H. Antin, Robert J. Soiffer, Jerome Ritz, John Koreth
Publikováno v:
Blood Advances, Vol 3, Iss 17, Pp 2550-2561 (2019)
Abstract: Low-dose interleukin-2 (IL-2) therapy for chronic graft-versus-host disease (cGVHD) generates a rapid rise in plasma IL-2 levels and CD4+CD25+CD127−Foxp3+ regulatory T-cell (CD4Treg) proliferation, but both decrease over time despite cont
Externí odkaz:
https://doaj.org/article/7451b006929a41fca3f95f87e7835ef3
Autor:
Max Jan, Matthew J. Leventhal, Elizabeth A. Morgan, Jordan C. Wengrod, Anwesha Nag, Samantha D. Drinan, Bruce M. Wollison, Matthew D. Ducar, Aaron R. Thorner, Scott Leppanen, Jane Baronas, Jonathan Stevens, William J. Lane, Natasha Kekre, Vincent T. Ho, John Koreth, Corey S. Cutler, Sarah Nikiforow, Edwin P. Alyea, III, Joseph H. Antin, Robert J. Soiffer, Jerome Ritz, R. Coleman Lindsley, Benjamin L. Ebert
Publikováno v:
Blood Advances, Vol 3, Iss 14, Pp 2199-2204 (2019)
Abstract: Immune evasion is a hallmark of cancer and a central mechanism underlying acquired resistance to immune therapy. In allogeneic hematopoietic cell transplantation (alloHCT), late relapses can arise after prolonged alloreactive T-cell control
Externí odkaz:
https://doaj.org/article/dd67bff001a141b5ae1e7eda4fd3a48d