Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Robert J, Majeska"'
Autor:
Abigail A Coffman, Jelena Basta‐Pljakic, Rosa M Guerra, Frank H Ebetino, Mark W Lundy, Robert J Majeska, Mitchell B Schaffler
Publikováno v:
JBMR Plus, Vol 5, Iss 7, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/39b83b895613419fbd0d9763b0efaee3
Autor:
Abigail A Coffman, Jelena Basta‐Pljakic, Rosa M Guerra, Frank H Ebetino, Mark W Lundy, Robert J Majeska, Mitchell B Schaffler
Publikováno v:
JBMR Plus, Vol 5, Iss 4, Pp n/a-n/a (2021)
ABSTRACT Bisphosphonates (BPs) are a mainstay of osteoporosis treatment; however, concerns about bone health based on oversuppression of remodeling remain. Long‐term bone remodeling suppression adversely affects bone material properties with microd
Externí odkaz:
https://doaj.org/article/7379c21f04d841a7a77d926f4a2a7532
Autor:
Daniel J. Leong, Marwa Choudhury, Regina Hanstein, David M. Hirsh, Sun Jin Kim, Robert J. Majeska, Mitchell B. Schaffler, John A. Hardin, David C. Spray, Mary B. Goldring, Neil J. Cobelli, Hui B. Sun
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-1 (2019)
Following publication of the original article [1], the authors reported an error in Figs. 2C and 5C.
Externí odkaz:
https://doaj.org/article/11a1159e8a124267a7828f7eb828308e
Autor:
Rosa M Guerra, Robert J. Majeska, Abigail A Coffman, Mitchell B. Schaffler, Mark W Lundy, Jelena Basta-Pljakic, Frank H. Ebetino
Publikováno v:
JBMR Plus, Vol 5, Iss 4, Pp n/a-n/a (2021)
JBMR Plus
JBMR Plus
Bisphosphonates (BPs) are a mainstay of osteoporosis treatment; however, concerns about bone health based on oversuppression of remodeling remain. Long‐term bone remodeling suppression adversely affects bone material properties with microdamage acc
Autor:
Jonathan Y Lee, Zuping Zhou, Peter J Taub, Melissa Ramcharan, Yonghui Li, Takintope Akinbiyi, Edward R Maharam, Daniel J Leong, Damien M Laudier, Takuya Ruike, Phillip J Torina, Mone Zaidi, Robert J Majeska, Mitchell B Schaffler, Evan L Flatow, Hui B Sun
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17531 (2011)
We characterized the differentiation of rat bone marrow-derived mesenchymal stem cells (BM-MSCs) into tenocyte-like cells in response to bone morphogenetic protein-12 (BMP-12). BM-MSCs were prepared from Sprague-Dawley rats and cultured as monolayers
Externí odkaz:
https://doaj.org/article/ae65fd77be85486589f50a62da92add4
Autor:
Mia M. Thi, Karl J. Lewis, Zeynep Seref-Ferlengez, Samuel Stephen, Sheldon Weinbaum, David C. Spray, Joyce Louie, Robert J. Majeska, Pamela Cabahug-Zuckerman, James F. Boorman-Padgett, Mitchell B. Schaffler, Jelena Basta-Pljakic
Publikováno v:
Bone
Microstructural adaptation of bone in response to mechanical stimuli is diminished with estrogen deprivation. Here we tested in vivo whether ovariectomy (OVX) alters the acute response of osteocytes, the principal mechanosensory cells of bone, to mec
Autor:
Sheldon Weinbaum, Dorra Frikha-Benayed, Samuel Stephen, Karl J. Lewis, Mitchell B. Schaffler, Mia M. Thi, Robert J. Majeska, Joyce Louie, Zeynep Seref-Ferlengez, David C. Spray
Publikováno v:
Proceedings of the National Academy of Sciences. 114:11775-11780
Osteocytes are considered to be the major mechanosensory cells of bone, but how osteocytes in vivo process, perceive, and respond to mechanical loading remains poorly understood. Intracellular calcium (Ca2+) signaling resulting from mechanical stimul
Autor:
Carol R. Flach, Serra Kaya, Luis Cardoso, Qihong Zhang, Robert J. Majeska, Shoshana Yakar, Timothy G. Bromage, Susannah P. Fritton, Jelena Basta-Pljakic, Richard Mendelsohn, Zeynep Seref-Ferlengez, Mitchell B. Schaffler
Publikováno v:
Journal of Bone and Mineral Research. 32:688-697
During lactation, mammals resorb mineral from the maternal skeleton to provide calcium to milk. Rodents lose 25% to 35% of skeletal ash weight, ash calcium content, and bone mineral content as measured by dual-energy X-ray absorptiometry (DXA), and h
Publikováno v:
Cells
Volume 8
Issue 10
Cells, Vol 8, Iss 10, p 1301 (2019)
Volume 8
Issue 10
Cells, Vol 8, Iss 10, p 1301 (2019)
Regenerative retinal therapies have introduced progenitor cells to replace dysfunctional or injured neurons and regain visual function. While contemporary cell replacement therapies have delivered retinal progenitor cells (RPCs) within customized bio
Publikováno v:
J Bone Miner Res
Localized apoptosis of osteocytes, the tissue-resident cells within bone, occurs with fatigue microdamage and activates bone resorption. Osteoclasts appear to target and remove dying osteocytes, resorbing damaged bone matrix as well. Osteocyte apopto