Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Robert J, Handa"'
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionMaternal adversity during pregnancy influences neurodevelopment in human and model animal offspring. Adversity can result from stressors coming from many different directions ranging from environmental to nutritional and physiological to
Externí odkaz:
https://doaj.org/article/efeb6da8a05743cea5096ce21332e529
Publikováno v:
BMC Neuroscience, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background The Period Circadian Regulator 2 (Per2) gene is important for the modulation of circadian rhythms that influence biological processes. Circadian control of the hypothalamus-pituitary-adrenal (HPA) axis is critical for regulation o
Externí odkaz:
https://doaj.org/article/675f89494b3d4c9dae7ec0ae1aeae1e7
Publikováno v:
Biology of Sex Differences, Vol 11, Iss 1, Pp 1-18 (2020)
Abstract Estradiol and testosterone are powerful steroid hormones that impact brain function in numerous ways. During development, these hormones can act to program the adult brain in a male or female direction. During adulthood, gonadal steroid horm
Externí odkaz:
https://doaj.org/article/e0f0bf6b90c14195ba8c1e7fc62d7fea
Autor:
Julietta A. Sheng, Natalie J. Bales, Sage A. Myers, Anna I. Bautista, Mina Roueinfar, Taben M. Hale, Robert J. Handa
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 14 (2021)
The hypothalamic-pituitary-adrenal axis is a complex system of neuroendocrine pathways and feedback loops that function to maintain physiological homeostasis. Abnormal development of the hypothalamic-pituitary-adrenal (HPA) axis can further result in
Externí odkaz:
https://doaj.org/article/1481119be7ff4d53861976bf9299551d
Autor:
Mario G. Oyola, Ryan C. Johnson, Bradly M. Bauman, Kenneth G. Frey, Ashley L. Russell, Madelaine Cho‐Clark, Katelyn N. Buban, Kimberly A. Bishop‐Lilly, D. Scott Merrell, Robert J. Handa, T. John Wu
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 4, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction The interaction between isoflavones and the gut microbiota has been highlighted as a potential regulator of obesity and diabetes. In this study, we examined the interaction between isoflavones and a shortened activity photoperio
Externí odkaz:
https://doaj.org/article/22b53387fddb4b678b8c6a121e393f24
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 323:E281-E289
Chronic stress is a significant risk factor for negative health outcomes. Furthermore, imbalance of autonomic nervous system control leads to dysregulation of physiological responses to stress and contributes to the pathogenesis of cardiometabolic an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8c45c29bc7e40c5e29cebe4d6ed3d8
https://doi.org/10.1152/ajpendo.00058.2022
https://doi.org/10.1152/ajpendo.00058.2022
Publikováno v:
Neuroscience. 496:105-118
The hypothalamic-pituitary-adrenal (HPA) axis mediates the physiological response to stressors and also synchronizes different physiological systems to environmental cues. Changes in day length (i.e., photoperiod) as well as chronic exposure to stres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df14c36602498ceb78d7cb78bafd0a6
https://doi.org/10.1016/j.neuroscience.2022.06.011
https://doi.org/10.1016/j.neuroscience.2022.06.011
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210272 (2019)
Processing of visual features related to objects and space relations occurs within separate cortical streams that interact with selective attention. Such separation has implications for cognitive development because the perception of 'what' and 'wher
Externí odkaz:
https://doaj.org/article/b488d6c622384b06b3f9854d9fe24efc
Publikováno v:
Androgens
Androgens play a pivotal role during development. These gonadal hormones and their receptors exert organizational actions that shape brain morphology in regions controlling the stress regulatory systems in a male-specific manner. Specifically, androg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b51da04ddb34268b39cf68afe64bee9
https://doi.org/10.1089/andro.2021.0021
https://doi.org/10.1089/andro.2021.0021
Publikováno v:
Journal of neuroendocrinologyREFERENCES. 34(12)
The ventromedial prefrontal cortex (vmPFC) regulates fear acquisition, fear extinction, mood, and HPA axis function. Multiple brain regions exhibit time-of-day dependent variations in learning, long term potentiation (LTP), and dendritic morphology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb3951534c360a4280964483d8b1ad8
https://pubmed.ncbi.nlm.nih.gov/36426781
https://pubmed.ncbi.nlm.nih.gov/36426781