Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Robert J, Duronio"'
Publikováno v:
Nucleus, Vol 14, Iss 1 (2023)
ABSTRACTHistone locus bodies (HLBs) are biomolecular condensates that assemble at replication-dependent (RD) histone genes in animal cells. These genes produce unique mRNAs that are not polyadenylated and instead end in a conserved 3’ stem loop cri
Externí odkaz:
https://doaj.org/article/7d9b984774114f61a95b3fdb78817a2b
Autor:
Evgeniya N Andreyeva, Alexander V Emelyanov, Markus Nevil, Lu Sun, Elena Vershilova, Christina A Hill, Michael-C Keogh, Robert J Duronio, Arthur I Skoultchi, Dmitry V Fyodorov
Publikováno v:
eLife, Vol 11 (2022)
Asynchronous replication of chromosome domains during S phase is essential for eukaryotic genome function, but the mechanisms establishing which domains replicate early versus late in different cell types remain incompletely understood. Intercalary h
Externí odkaz:
https://doaj.org/article/0833503e9fc24f78babb97c5408c50f8
Autor:
Joy H Meserve, Robert J Duronio
Publikováno v:
eLife, Vol 10 (2021)
A new imaging approach can distinguish between cells destined to stop proliferating and those committed to re-entering the cell cycle in live animals.
Externí odkaz:
https://doaj.org/article/0258cca483704b9ea3eca38de8276c6d
Autor:
Michael P. Meers, Karen Adelman, Robert J. Duronio, Brian D. Strahl, Daniel J. McKay, A. Gregory Matera
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-20 (2018)
Abstract Background High-resolution transcription start site (TSS) mapping in D. melanogaster embryos and cell lines has revealed a rich and detailed landscape of both cis- and trans-regulatory elements and factors. However, TSS profiling has not bee
Externí odkaz:
https://doaj.org/article/7a89212ac91d47e7bbb38f4f071a3e5f
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 12, Pp 1381-1389 (2017)
For hundreds of years, biologists have studied accessible organisms such as garden peas, sea urchins collected at low tide, newt eggs, and flies circling rotten fruit. These organisms help us to understand the world around us, attracting and inspirin
Externí odkaz:
https://doaj.org/article/8cb9b4eaaa5d430a995436f5e44beb81
Autor:
Mary Leatham-Jensen, Christopher M Uyehara, Brian D Strahl, A Gregory Matera, Robert J Duronio, Daniel J McKay
Publikováno v:
PLoS Genetics, Vol 15, Iss 1, p e1007932 (2019)
Proper determination of cell fates depends on epigenetic information that is used to preserve memory of decisions made earlier in development. Post-translational modification of histone residues is thought to be a central means by which epigenetic in
Externí odkaz:
https://doaj.org/article/64e708b80a654723816a3b9ae0d9476e
Autor:
Jeanne-Marie E. McPherson, Lucy C. Grossmann, Robin L. Armstrong, Esther Kwon, Harmony R. Salzler, A. Gregory Matera, Daniel J. McKay, Robert J. Duronio
Publikováno v:
bioRxiv
The chromatin of animal cells contains two types of histones: canonical histones that are expressed during S phase of the cell cycle to package the newly replicated genome, and variant histones with specialized functions that are expressed throughout
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d937a966806596e4043308d12aad4819
https://europepmc.org/articles/PMC10081267/
https://europepmc.org/articles/PMC10081267/
Autor:
Harmony R. Salzler, Vasudha Vandadi, Benjamin D. McMichael, John C. Brown, Sally A. Boerma, Mary P. Leatham-Jensen, Kirsten M. Adams, Michael P. Meers, Jeremy M. Simon, Robert J. Duronio, Daniel J. McKay, A. Gregory Matera
Publikováno v:
Science Advances. 9
Polycomb complexes regulate cell type–specific gene expression programs through heritable silencing of target genes. Trimethylation of histone H3 lysine 27 (H3K27me3) is essential for this process. Perturbation of H3K36 is thought to interfere with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ef3efe17bdc77106b4d76894e3433de
https://doi.org/10.1126/sciadv.adf2451
https://doi.org/10.1126/sciadv.adf2451
Autor:
Christopher Abdullah, Robert J Duronio
Publikováno v:
PLoS Genetics, Vol 14, Iss 11, p e1007728 (2018)
Externí odkaz:
https://doaj.org/article/965b39fa9eff4a23b14206947d4b5730
Autor:
Alexander V Emelyanov, Evgeniya N Andreyeva, Markus Nevil, Lu Sun, Elena Vershilova, Christina A Hill, Michael-C Keogh, Robert J Duronio, Arthur I Skoultchi, Dmitry V Fyodorov
Publikováno v:
eLife. 11
Asynchronous replication of chromosome domains during S phase is essential for eukaryotic genome function, but the mechanisms establishing which domains replicate early versus late in different cell types remain incompletely understood. Intercalary h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c07aecb921cf65ac09f5e7ea5c7c9b0e
https://doi.org/10.7554/elife.81828
https://doi.org/10.7554/elife.81828