Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Robert J, Distel"'
Autor:
Karyn Schmidt, Cailin E. Joyce, Frank Buquicchio, Adam Brown, Justin Ritz, Robert J. Distel, Charles H. Yoon, Carl D. Novina
Publikováno v:
Cell Reports, Vol 15, Iss 9, Pp 2025-2037 (2016)
Long non-coding RNAs (lncRNAs) have been implicated in numerous physiological processes and diseases, most notably cancers. However, little is known about the mechanism of many functional lncRNAs. We identified an abundantly expressed lncRNA associat
Externí odkaz:
https://doaj.org/article/a0d312177fc84848ba8b1e3d13f865fa
Autor:
Fatemeh eMomen-Heravi, Leonora eBalaj, Sara eAlian, John eTigges, Vasilis eToxavidis, Maria eEricsson, Robert J Distel, Alexander R Ivanov, Johan eSkog, Winston Patrick Kuo
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
Extracellular vesicles are nano-sized vesicles released by all cells in vitro as well as in vivo. Their role has been implicated mainly in cell-cell communication, but also in disease biomarkers and more recently in gene delivery. They represent a sn
Externí odkaz:
https://doaj.org/article/d83fc9a9d5574194934768640a25eadc
Autor:
William C. Forrester, Alexia T. Kedves, Quang-Dé Nguyen, Dennis M. Bonal, Sneha Sanghavi, Prafulla C. Gokhale, Elizabeth George, Fred Harbinski, Robert J. Distel, Paul Kirschmeier, Scott Gleim, Michael S. Goldberg, Christina Benander, Xiaoyou Liang, Jeremy L. Jenkins, Frederic Sigoillot
Publikováno v:
Journal of Clinical Investigation. 127:4554-4568
Transcriptional repression of ubiquitin B (UBB) is a cancer-subtype-specific alteration that occurs in a substantial population of patients with cancers of the female reproductive tract. UBB is 1 of 2 genes encoding for ubiquitin as a polyprotein con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d190d88b06e78c55a0435fa13b13fe74
https://doi.org/10.1172/jci92914
https://doi.org/10.1172/jci92914
Autor:
Andrew H. Rogers, Sara Thiede, Robert J. Distel, Kristi Vetrand, Yanan Kuang, Pasi A. Jänne, Mike Makrigiorgos, Beow Y. Yeap, Lilin Wang
Publikováno v:
Clinical Cancer Research. 15:2630-2636
Purpose: Tumors from 50% of epidermal growth factor receptor (EGFR) mutant non–small cell lung cancer patients that develop resistance to gefitinib or erlotinib will contain a secondary EGFR T790M mutation. As most patients do not undergo repeated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3499f797c7c0c2022cbb5bf8c383fb4d
https://doi.org/10.1158/1078-0432.ccr-08-2592
https://doi.org/10.1158/1078-0432.ccr-08-2592
Autor:
Elizabeth A. Maher, Balazs Halmos, Matthew Meyerson, Jeffrey C. Lee, Neal I. Lindeman, Victoria A. Joshi, Robert J. Distel, Pasi A. Jänne, Andrew M. Rogers, Ana M. Borras, Bruce E. Johnson, Hema Liyanage, Yanan Kuang
Publikováno v:
Clinical Cancer Research. 12:751-758
Purpose: Mutations in the epidermal growth factor receptor (EGFR) are associated with clinical and radiographic responses to EGFR tyrosine kinase inhibitors gefitinib and erlotinib. Currently available methods of EGFR mutation detection rely on direc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d824e7e2c0ae92a3ad061e5556be29e
https://doi.org/10.1158/1078-0432.ccr-05-2047
https://doi.org/10.1158/1078-0432.ccr-05-2047
Autor:
Edward M. Suh, Robert J. Distel, Joseph W. Gibson, Smaranda Bacanu, Magnus Neumuller, Geoffrey I. Shapiro, Sara Lööf, John Hilton, Pawel Niekrasz, Leena Gandhi, Nicole G. Chau, Takahiro Seki, Khan Do, Mattias Bergqvist
Publikováno v:
Cancer Research. 77:2340-2340
Selective CDK4/6 inhibition is now part of standard treatment for HR+ breast cancer. There is a pressing need for a practical biomarker that can provide early indication of the biologic activity of these agents and correlate with clinical outcome. Ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24afbca0bca6fe9cc86563364a9156a0
https://doi.org/10.1158/1538-7445.am2017-2340
https://doi.org/10.1158/1538-7445.am2017-2340
Publikováno v:
Journal of Biological Methods. 4:e67
Long non-coding RNAs (lncRNAs) regulate critical cellular processes and their dysregulation contributes to multiple diseases. Although only a few lncRNAs have defined mechanisms, many of these characterized lncRNAs interact with transcription factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3256b6d1399fcf3aa5079f598c863d6
https://doi.org/10.14440/jbm.2017.171
https://doi.org/10.14440/jbm.2017.171
Autor:
Isabelle, Desitter, Bella S, Guerrouahen, Naoual, Benali-Furet, Janine, Wechsler, Pasi A, Jänne, Yanan, Kuang, Masahiko, Yanagita, Lilin, Wang, Jillian A, Berkowitz, Robert J, Distel, Yvon E, Cayre
Publikováno v:
Anticancer research. 31(2)
Circulating tumor cells (CTCs) likely derive from clones in the primary tumor, suggesting that they can be used for all biological tests applying to the primary cells.The ScreenCell® devices are single-use and low-cost innovative devices that use a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b4482d73b1900ca7207258a2a3448837
https://pubmed.ncbi.nlm.nih.gov/21378321
https://pubmed.ncbi.nlm.nih.gov/21378321
Publikováno v:
Journal of Biological Chemistry. 267:5937-5941
Fatty acids are important metabolic substrates and may also be involved in pathological syndromes such as the insulin resistance of diabetes and obesity. We demonstrate here that fatty acids can regulate specific gene expression; mRNAs encoding the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1306fbff21d779626f4d101056249a12
https://doi.org/10.1016/s0021-9258(18)42645-2
https://doi.org/10.1016/s0021-9258(18)42645-2
Publikováno v:
Nucleic Acids Research
The rapidly growing understanding of human genetic pathways, including those that mediate cancer biology and drug response, leads to an increasing need for extensive and reliable mutation screening on a population or on a single patient basis. Here w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913bbdb5b6b0e55ebdb8284f61d14053