Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Robert I. Cargill"'
Publikováno v:
British Journal of Clinical Pharmacology. 43:309-313
AIMS Diuretic therapy is conventionally used to treat oedema in patients with hypoxic cor pulmonale. This condition is associated with activation of the renin angiotensin system (RAS) with elevated levels of angiotensin II (ANG II), a potent pulmonar
Autor:
Robert I. Cargill, Brian J. Lipworth
Publikováno v:
Chest. 110:1220-1225
We have studied the hemodynamic and hormonal effects of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) in eight patients with cor pulmonale. Subjects were studied twice and were given a 20-min placebo infusion followed by either
Publikováno v:
Chest. 110:698-703
Study objective We examined the hypothesis that angiotensin II (ANG II) is a modulator of pulmonary vascular tone by examining the effects of ANG II blockade on pulmonary hemodynamics during normoxemia and hypoxemia in normal volunteers with an activ
Publikováno v:
Chest. 109:1215-1221
Study objective The inotropic, lusitropic, and electrophysiologic effects of acute hypercapnia in humans are not known. Although the effects of hypercapnia on the systemic circulation have been well documented, there is still some debate as to whethe
Publikováno v:
Thorax. 51:262-266
BACKGROUND: A study was performed to compare the adrenal suppression caused by inhaled fluticasone propionate and budesonide on a microgram equivalent basis, each given by metered dose inhaler to asthmatic patients. METHODS: Twelve asthmatic patients
Autor:
Robert I. Cargill, Brian J. Lipworth
Publikováno v:
Chest. 109:424-429
Objective We have studied the effects of angiotensin-converting enzyme (ACE) inhibition with lisinopril on acute hypoxic pulmonary vasoconstriction (HPV). Design Randomized, double-blind, placebo-controlled study in ten healthy volunteers. Subjects r
Publikováno v:
Chest. 109:343-347
The aim of the study was to evaluate the facilitatory effects of inhaled corticosteroid on in vitro parameters of lymphocyte beta 2-adrenoceptor function in asthmatic patients. Serum cortisol level was also evaluated as a measure of systemic bioactiv
Publikováno v:
European Journal of Applied Physiology and Occupational Physiology. 72:256-260
We have studied the integrated neuroendocrine and haemodynamic effects of acute hypoxaemia in ten healthy volunteers studied on two separate occasions. After reaching a resting haemodynamic state, subjects breathed either room air or a nitrogen/oxyge
Publikováno v:
Cardiovascular Research. 30:875-880
Objectives: We examined the hypothesis that angiotensin II (ANG II) is a modulator of acute hypoxic pulmonary vasoconstriction (HPV) by looking at the effect of losartan, a selective type 1 ANG II receptor antagonist, on acute HPV in man. Methods: Te
Publikováno v:
Chest. 108:899-902
Study objective Although some of the cardiovascular responses to hypoxemia are well described, effects on myocardial contractility have not been defined. Such effects are readily assessed by noninvasive techniques and we have therefore evaluated Dopp