Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Robert Hennze"'
Autor:
Thomas Hoyler, Bettina Bannert, Cédric André, Damian Beck, Thomas Boulay, David Buffet, Nadja Caesar, Thomas Calzascia, Janet Dawson, Diego Kyburz, Robert Hennze, Christine Huppertz, Amanda Littlewood-Evans, Pius Loetscher, Kirsten D. Mertz, Satoru Niwa, Gautier Robert, James S. Rush, Giulia Ruzzante, Sophie Sarret, Thomas Stein, Ismahane Touil, Grazyna Wieczorek, Geraldine Zipfel, Stuart Hawtin, Tobias Junt
Publikováno v:
JCI Insight, Vol 7, Iss 13 (2022)
IL-1 receptor-activated kinase 1 (IRAK1) is involved in signal transduction downstream of many TLRs and the IL-1R. Its potential as a drug target for chronic inflammatory diseases is underappreciated. To study its functional role in joint inflammatio
Externí odkaz:
https://doaj.org/article/6fc6e2c6d008483f99d660e2370be0ce
Autor:
Christine Ljungberg, Christine Huppertz, Kirsten Rønholt, Robert Hennze, Thomas Litman, Claus Johansen, Lars Iversen, Trine Bertelsen
Publikováno v:
Bertelsen, T, Ljungberg, C, Litman, T, Huppertz, C, Hennze, R, Rønholt, K, Iversen, L & Johansen, C 2020, ' IκBζ is a key player in the antipsoriatic effects of secukinumab ', The Journal of allergy and clinical immunology, vol. 145, no. 1, pp. 379-390 . https://doi.org/10.1016/j.jaci.2019.09.029
Bertelsen, T, Ljungberg, C, Litman, T, Huppertz, C, Hennze, R, Rønholt, K, Iversen, L & Johansen, C 2020, ' IκBζ is a key player in the antipsoriatic effects of secukinumab ', Journal of Allergy and Clinical Immunology, vol. 145, no. 1, pp. 379-390 . https://doi.org/10.1016/j.jaci.2019.09.029
Bertelsen, T, Ljungberg, C, Litman, T, Huppertz, C, Hennze, R, Rønholt, K, Iversen, L & Johansen, C 2020, ' IκBζ is a key player in the antipsoriatic effects of secukinumab ', Journal of Allergy and Clinical Immunology, vol. 145, no. 1, pp. 379-390 . https://doi.org/10.1016/j.jaci.2019.09.029
BACKGROUND: IκBζ plays a key role in psoriasis by mediating IL-17A-driven effects, but the molecular mechanism by which IL-17A regulates IκBζ expression is not clarified.OBJECTIVE: We sought to explore the molecular transformation in patients wit