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pro vyhledávání: '"Robert Hennis"'
Autor:
Fabiola Ramirez, Angelica Zambrano, Robert Hennis, Nathan Holland, Rajkumar Lakshmanaswamy, Jessica Chacon
Publikováno v:
Vaccines, Vol 11, Iss 9, p 1465 (2023)
While cancer immunotherapies have become central to treatment, challenges associated with the ability of tumors to evade the immune system remain significant obstacles. At the heart of this issue is the tumor immune microenvironment, the complex inte
Externí odkaz:
https://doaj.org/article/3cedad4a5b754cbbba09ec82170ead7f
Autor:
Clare L M LeGuyader, Michael K. Gilson, Michael D. Burkart, Arnold Garcia, Nathan C. Gianneschi, Jin Yang, Paul A. Bertin, Jeremiah D. Momper, Niel M. Henriksen, Christopher V. Barback, Matt J. Jaremko, Spencer T Burton, Cassandra E. Callmann, Matthew P. Thompson, Warren C. W. Chan, Robert Hennis
Publikováno v:
Journal of the American Chemical Society
We describe the design, synthesis, and antitumor activity of an 18 carbon α,ω-dicarboxylic acid monoconjugated via an ester linkage to paclitaxel (PTX). This 1,18-octadecanedioic acid-PTX (ODDA-PTX) prodrug readily forms a noncovalent complex with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973c7d21ae614ef3e358991a71cec33a
https://pubmed.ncbi.nlm.nih.gov/31317744
https://pubmed.ncbi.nlm.nih.gov/31317744