Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Robert Hauffe"'
Autor:
Robert Hauffe, Michaela Rath, Mareike Schell, Katrin Ritter, Kai Kappert, Stefanie Deubel, Christiane Ott, Markus Jähnert, Wenke Jonas, Annette Schürmann, André Kleinridders
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101276- (2021)
Objective: Insulin regulates mitochondrial function, thereby propagating an efficient metabolism. Conversely, diabetes and insulin resistance are linked to mitochondrial dysfunction with a decreased expression of the mitochondrial chaperone HSP60. Th
Externí odkaz:
https://doaj.org/article/8e70c968a1694ff39c2a66f6cc5ab0a2
Autor:
Kristina Wardelmann, Sabine Blümel, Michaela Rath, Eugenia Alfine, Chantal Chudoba, Mareike Schell, Weikang Cai, Robert Hauffe, Kathrin Warnke, Tanina Flore, Katrin Ritter, Jürgen Weiß, C. Ronald Kahn, André Kleinridders
Publikováno v:
Molecular Metabolism, Vol 21, Iss , Pp 68-81 (2019)
Objective: Insulin action in the brain controls metabolism and brain function, which is linked to proper mitochondrial function. Conversely, brain insulin resistance associates with mitochondrial stress and metabolic and neurodegenerative diseases. I
Externí odkaz:
https://doaj.org/article/7c9d14609d4c4b8591384c45fafcc306
Autor:
Robert Hauffe, Michaela Rath, Wilson Agyapong, Wenke Jonas, Heike Vogel, Tim J. Schulz, Maria Schwarz, Anna P. Kipp, Matthias Blüher, André Kleinridders
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 862 (2022)
The intake of high-fat diets (HFDs) containing large amounts of saturated long-chain fatty acids leads to obesity, oxidative stress, inflammation, and insulin resistance. The trace element selenium, as a crucial part of antioxidative selenoproteins,
Externí odkaz:
https://doaj.org/article/f0df0dd7af6b4c95b7dab059e4dcf45b
Autor:
Kristina Wardelmann, Michaela Rath, José Pedro Castro, Sabine Blümel, Mareike Schell, Robert Hauffe, Fabian Schumacher, Tanina Flore, Katrin Ritter, Andreas Wernitz, Toru Hosoi, Koichiro Ozawa, Burkhard Kleuser, Jürgen Weiß, Annette Schürmann, André Kleinridders
Publikováno v:
Antioxidants, Vol 10, Iss 5, p 711 (2021)
Mitochondria are critical for hypothalamic function and regulators of metabolism. Hypothalamic mitochondrial dysfunction with decreased mitochondrial chaperone expression is present in type 2 diabetes (T2D). Recently, we demonstrated that a dysregula
Externí odkaz:
https://doaj.org/article/9db7b1040f554f3f80b1b7f6dd84a90e
Publikováno v:
Diabetologie und Stoffwechsel.
Autor:
Mareike Schell, Kristina Wardelmann, Robert Hauffe, Michaela Rath, Simran Chopra, André Kleinridders
Publikováno v:
Biological Psychiatry Global Open Science.
Publikováno v:
Physiological Consequences of Brain Insulin Action ISBN: 9781003079927
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47c055ecdb0ed491893b5e9a6e2d038e
https://doi.org/10.1201/9781003079927-1
https://doi.org/10.1201/9781003079927-1
Autor:
MAREIKE SCHELL, KRISTINA WARDELMANN, ROBERT HAUFFE, MICHAELA RATH, SIMRAN CHOPRA, ANDRE KLEINRIDDERS
Publikováno v:
Diabetes. 71
Prevalence of depression is higher in diabetic patients compared to healthy humans due to a shared pathogenesis including insulin resistance and inflammation. These factors are also linked to intestinal dysbiosis. Interestingly, preventive intake of
Publikováno v:
Diabetes. 71
The loss of insulin receptor (IR) in white adipose tissue (WAT) is a feature of type 2 diabetes. Previously, we have demonstrated that feeding mice a preventive selenium rich HFD (SRHFD) , while not influencing obesity development, counteracted diet-
Publikováno v:
Präzisionsmedizin – Eine Reise in die Zukunft der Diabetologie www.diabeteskongress.de.