Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Robert H.I. Andtbacka"'
Autor:
Robert H.I. Andtbacka, Thomas Amatruda, John Nemunaitis, Jonathan S. Zager, John Walker, Jason A. Chesney, Kate Liu, Cheng-Pang Hsu, Cheryl A. Pickett, Janice M. Mehnert
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 89-97 (2019)
Background: Talimogene laherparepvec (T-VEC) is an intralesionally delivered, modified herpes simplex virus type-1 oncolytic immunotherapy. The biodistribution, shedding, and potential transmission of T-VEC was systematically evaluated during and aft
Externí odkaz:
https://doaj.org/article/c636d98304cf434ca98de4705a2ed3ba
Autor:
Robert H.I. Andtbacka, Yan Wang, Robert H. Pierce, Jean S. Campbell, Melinda Yushak, Mohammed Milhem, Merrick Ross, Katie Niland, Robert D. Arbeit, Sudha Parasuraman, Kris Bickley, Cecilia CS Yeung, Lauri D. Aicher, Kimberly S. Smythe, Lu Gan
Publikováno v:
Cancer Research Communications. 2:904-913
Purpose: Mavorixafor is an oral, selective inhibitor of the CXCR4 chemokine receptor that modulates immune cell trafficking. A biomarker-driven phase Ib study (NCT02823405) was conducted in 16 patients with melanoma to investigate the hypothesis that
Autor:
Jason J. Luke, Nitya Nair, Thomas Müller, Sarah M. McWhirter, Thomas W. Dubensky, Jincheng Wu, Xueying Chen, Marc Pelletier, Xinhui Chen, Nancy Lewis, Matthew Ingham, Robert H.I. Andtbacka, Wells A. Messersmith, F. Stephen Hodi, Randy F. Sweis, Funda Meric-Bernstam
Purpose:This phase I study assessed the safety, pharmacokinetics (PKs), and efficacy of MIW815 (ADU-S100), a novel synthetic cyclic dinucleotide that activates the stimulator of IFN genes (STING) pathway, in patients with advanced/metastatic cancers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6471c109b1cd60d440234d0654a35648
https://doi.org/10.1158/1078-0432.c.6530796.v2
https://doi.org/10.1158/1078-0432.c.6530796.v2
Autor:
Jason J. Luke, Nitya Nair, Thomas Müller, Sarah M. McWhirter, Thomas W. Dubensky, Jincheng Wu, Xueying Chen, Marc Pelletier, Xinhui Chen, Nancy Lewis, Matthew Ingham, Robert H.I. Andtbacka, Wells A. Messersmith, F. Stephen Hodi, Randy F. Sweis, Funda Meric-Bernstam
Immunohistochemistry of injected and noninjected lesions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742b68cebc5eae1e4fabc59407f5290a
https://doi.org/10.1158/1078-0432.22709644
https://doi.org/10.1158/1078-0432.22709644
Autor:
Jason J. Luke, Nitya Nair, Thomas Müller, Sarah M. McWhirter, Thomas W. Dubensky, Jincheng Wu, Xueying Chen, Marc Pelletier, Xinhui Chen, Nancy Lewis, Matthew Ingham, Robert H.I. Andtbacka, Wells A. Messersmith, F. Stephen Hodi, Randy F. Sweis, Funda Meric-Bernstam
Supplementary tables and figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c823bec3efea05fdab1d3cfb84a070
https://doi.org/10.1158/1078-0432.22709635.v1
https://doi.org/10.1158/1078-0432.22709635.v1
Autor:
Lu Gan, Kimberly S. Smythe, Lauri D. Aicher, Cecilia CS Yeung, Kris Bickley, Sudha Parasuraman, Robert D. Arbeit, Katie Niland, Merrick Ross, Mohammed Milhem, Melinda Yushak, Jean S. Campbell, Robert H. Pierce, Yan Wang, Robert H.I. Andtbacka
Antibody panels used for mIF analyses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d2a1af716f0bd76c6e9fa7b043dbd23
https://doi.org/10.1158/2767-9764.22545773.v1
https://doi.org/10.1158/2767-9764.22545773.v1
Autor:
Lu Gan, Kimberly S. Smythe, Lauri D. Aicher, Cecilia CS Yeung, Kris Bickley, Sudha Parasuraman, Robert D. Arbeit, Katie Niland, Merrick Ross, Mohammed Milhem, Melinda Yushak, Jean S. Campbell, Robert H. Pierce, Yan Wang, Robert H.I. Andtbacka
Serum cytokine and chemokine changes at the end of the 3-week monotherapy period compared to baseline.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c5098d1822b7b01f14f78eb4c3a72ba
https://doi.org/10.1158/2767-9764.22545770.v1
https://doi.org/10.1158/2767-9764.22545770.v1
Autor:
Lu Gan, Kimberly S. Smythe, Lauri D. Aicher, Cecilia CS Yeung, Kris Bickley, Sudha Parasuraman, Robert D. Arbeit, Katie Niland, Merrick Ross, Mohammed Milhem, Melinda Yushak, Jean S. Campbell, Robert H. Pierce, Yan Wang, Robert H.I. Andtbacka
Purpose:Mavorixafor is an oral, selective inhibitor of the CXCR4 chemokine receptor that modulates immune cell trafficking. A biomarker-driven phase Ib study (NCT02823405) was conducted in 16 patients with melanoma to investigate the hypothesis that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412d1a88bdb6c622134f34d6dd3e332d
https://doi.org/10.1158/2767-9764.c.6551033.v1
https://doi.org/10.1158/2767-9764.c.6551033.v1
Autor:
Lu Gan, Kimberly S. Smythe, Lauri D. Aicher, Cecilia CS Yeung, Kris Bickley, Sudha Parasuraman, Robert D. Arbeit, Katie Niland, Merrick Ross, Mohammed Milhem, Melinda Yushak, Jean S. Campbell, Robert H. Pierce, Yan Wang, Robert H.I. Andtbacka
Shared TCR TIL sequences taken from tumor biopsy of patient #5 at various timepoints.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a79627298ef8dc5b78551cef478a86
https://doi.org/10.1158/2767-9764.22545779.v1
https://doi.org/10.1158/2767-9764.22545779.v1
Autor:
Lu Gan, Kimberly S. Smythe, Lauri D. Aicher, Cecilia CS Yeung, Kris Bickley, Sudha Parasuraman, Robert D. Arbeit, Katie Niland, Merrick Ross, Mohammed Milhem, Melinda Yushak, Jean S. Campbell, Robert H. Pierce, Yan Wang, Robert H.I. Andtbacka
Depiction of T cell clone mobilization from peripheral blood to melanoma site on day 1 and at EOT.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e18f10426dc9934d3fce1d6e4d95278
https://doi.org/10.1158/2767-9764.22545776
https://doi.org/10.1158/2767-9764.22545776