Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Robert H. Utama"'
Autor:
Robert H. Utama, Lakmali Atapattu, Aidan P. O'Mahony, Christopher M. Fife, Jongho Baek, Théophile Allard, Kieran J. O'Mahony, Julio C.C. Ribeiro, Katharina Gaus, Maria Kavallaris, J. Justin Gooding
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101621- (2020)
Summary: 3D in vitro cancer models are important therapeutic and biological discovery tools, yet formation of matrix-embedded multicellular spheroids prepared in high-throughput (HTP), and in a highly controlled manner, remains challenging. This is i
Externí odkaz:
https://doaj.org/article/63f81ea7be96472d9d5abc0a544d4d1a
Autor:
Duyen H. T. Nguyen, Robert H. Utama, Kristel C. Tjandra, Panthipa Suwannakot, Eric Y. Du, Maria Kavallaris, Richard D. Tilley, J. Justin Gooding
Publikováno v:
Biomacromolecules. 24:57-68
Autor:
Hongxu Lu, Amanda Abboud, Robert H. Utama, Martina H. Stenzel, Samuel Pearson, Janina-Miriam Noy, Vien T. Huynh
Publikováno v:
ACS macro letters. 2(3)
Nanodiamonds (NDs) are highly promising drug carriers due to their biocompatibility, manipulable surface chemistry, and nonbleaching flourescence. In this communication, we compare the cytotoxicity of three ND-cisplatin systems in which cisplatin was
Autor:
MoonSun Jung, Joanna N. Skhinas, Eric Y. Du, M.A. Kristine Tolentino, Robert H. Utama, Martin Engel, Alexander Volkerling, Andrew Sexton, Aidan P. O’Mahony, Julio C. C. Ribeiro, J. Justin Gooding, Maria Kavallaris
SummaryUnderstanding the underlying mechanisms of migration and metastasis is a key focus of cancer research. There is an urgent need to developin vitro3D tumor models that can mimic physiological cell-cell and cell-extracellular matrix interactions,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2543ae9109917f4dd1576103df66dd
https://doi.org/10.1101/2021.12.28.474387
https://doi.org/10.1101/2021.12.28.474387
Three-dimensional (3D) bioprinting has revolutionised the field of biofabrication by delivering precise, cost-effective and a relatively simple way of engineeringin vitroliving systems in high volume for use in tissue regeneration, biological modelli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77288239bc8378a00ea368e32d462d06
https://hdl.handle.net/10453/154373
https://hdl.handle.net/10453/154373
Autor:
Dinisha Govender, Samuel Bax, Geraldine M. O'Neill, Martin Engel, Robert H. Utama, Louise Orcheston-Findlay
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 2962, p 2962 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 2962, p 2962 (2021)
The life expectancy of patients with high-grade glioma (HGG) has not improved in decades. One of the crucial tools to enable future improvement is advanced models that faithfully recapitulate the tumour microenvironment; they can be used for high-thr
Autor:
Robert H. Utama, Aidan P. O’Mahony, Vincent T. G. Tan, Andrew Sexton, J. Justin Gooding, Maria Kavallaris, Julio C. C. Ribeiro, Duyen H. T. Nguyen, Kristel C Tjandra
In vitro three-dimensional (3D) cell models have been accepted to better recapitulate aspects of in vivo organ environment than 2D cell culture. Currently, the production of these complex in vitro 3D cell models with multiple cell types and microenvi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48f21dde37ef85681f0f2c787108ac63
https://doi.org/10.1101/2021.02.18.431759
https://doi.org/10.1101/2021.02.18.431759
Autor:
Jongho Baek, Julio C. C. Ribeiro, Katharina Gaus, Théophile Allard, Aidan P. O’Mahony, Kieran J. O'Mahony, J. Justin Gooding, Christopher M. Fife, Maria Kavallaris, Lakmali Atapattu, Robert H. Utama
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101621-(2020)
iScience
iScience
Summary 3D in vitro cancer models are important therapeutic and biological discovery tools, yet formation of matrix-embedded multicellular spheroids prepared in high-throughput (HTP), and in a highly controlled manner, remains challenging. This is im
Autor:
Lakmali Atapattu, Christopher M. Fife, Katharina Gaus, Aidan P. O’Mahony, Robert H. Utama, J. Justin Gooding, Jongho Baek, Maria Kavallaris, Julio C. C. Ribeiro, Théophile Allard, Kieran J. O'Mahony
3D in vitro cancer models are important therapeutic and biological discovery tools, yet formation of multicellular spheroids in a throughput and highly controlled manner to achieve robust and statistically relevant data, remains challenging. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540b3c5a9d99e780024014433e3a2db6
Publikováno v:
14th Pacific Rim Conference on Lasers and Electro-Optics (CLEO PR 2020).
We apply Brillouin microscopy to characterize micromechanical properties of 3D bioprinted hydrogel constructs. Non-contact and label-free mapping of constructs’ mechanical properties in situ provides invaluable insight into spatial distribution and