Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Robert H. McLean"'
Autor:
John FitzGerald, Julien Dedier, Diana D Marini, Kenneth G. Saag, Lynn B. Oertel, Fred Murray, Michael A. Fischer, Joel S. Weissman, Erica Hinteregger, Robert H. McLean, Dong Hyun Suh, Hyon K. Choi, Michael J. Barry, Cesar Berardinelli, Tuhina Neogi, Michael H. Pillinger, Brianne Johnsen, Steven J. Atlas, Daniel H. Solomon, James Watkins, Kevin R. Riggs
Publikováno v:
ACR Open Rheumatology
ACR Open Rheumatology, Vol 3, Iss 5, Pp 341-348 (2021)
ACR open rheumatology, vol 3, iss 5
ACR Open Rheumatology, Vol 3, Iss 5, Pp 341-348 (2021)
ACR open rheumatology, vol 3, iss 5
Objective Disagreement exists between rheumatology and primary care societies regarding gout management. This paper describes a formal process for gathering input from stakeholders in the planning of a trial to compare gout management strategies. Met
Publikováno v:
Medical Quality Management ISBN: 9783030480790
As healthcare organizations examine how to design and adapt their management structures to ensure quality is being measured and improved, considerations around the functioning of systems and the management of change become crucial. The inherent finan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1956eef86cc2cb84c7013717122a38c
https://doi.org/10.1007/978-3-030-48080-6_8
https://doi.org/10.1007/978-3-030-48080-6_8
Autor:
John A. Phillips, Robert H. McLean, Tao Wang, Robert J. Wyatt, Bruce A. Julian, Gary Niblack, David Valle, Jerry A. Winkelstein, Timothy S. Collins
Publikováno v:
Journal of Biological Chemistry. 269:27727-27731
The fourth component of complement (C4) is encoded by two highly homologous genes, C4A and C4B. Only one hemolytically inactive C4A allotype (C4A6) has been reported. No hemolytically inactive C4B allotype has been described. We report the first hemo
Publikováno v:
Medicine. 72:236-244
We studied 121 patients with systemic lupus erythematosus (SLE), of whom 119 were complement typed. Both black and white patients with SLE were more likely than racially matched controls to have a C4A null allotype. Patients with homozygous C4A defic
Publikováno v:
Journal of Clinical Investigation. 90:1180-1184
The fourth component of complement (C4) is encoded by two closely linked genes (C4A and C4B) within the MHC. Null alleles at either locus (C4AQ0 or C4BQ0) are relatively common, occurring at the C4A locus in approximately 10% of normal individuals an
Publikováno v:
MEDICINE. 71:84-95
We examined 18 families with infants who had neonatal lupus erythematosus (NLE) syndrome to determine whether abnormalities in C4 phenotypes and genotypes were an additional risk factor for this syndrome. Fifteen of 18 mothers of infants with NLE (83
Autor:
Peter L. Havens, Robert H. McLean, Morey W. Haymond, Jean S. Kan, Saul W. Brusilow, S. Lane Rutledge
Publikováno v:
The Journal of Pediatrics. 116:125-128
Maple syrup urine disease and argininosuccinate synthetase deficiency are two of many inborn errors of metabolism that may result in neonatal encephalopathy. Early treatment is designed to suppress endogenous proteolysis and amino acid catabolism wit
Autor:
Robert J. Wyatt, F. Bryson Waldo, Marian L. Rivas, Robert H. McLean, Jiang Bin, Shane Roy, F. Bruder Stapleton, Bettina H. Ault
Publikováno v:
The Journal of Pediatrics. 117:753-755
Publikováno v:
Pediatric Nephrology. 4:597-599
In a girl with recurrent haemolytic uraemic syndrome (HUS), persistently low serum levels of C3 were found. Analysis of complement phenotype revealed a hypomorphic variant of C3 Fast in the patient (C3fS) and a normal heterozygous pattern in both par
Autor:
Robert H. McLean
Publikováno v:
Pediatric nephrology (Berlin, Germany). 7(2)
The complement (C) system in man and its relationship to disease has been the subject of intensive research. In this review, we update the information concerning the nature of the various C components, and present some of the similarities between str