Zobrazeno 1 - 10 of 44 pro vyhledávání: '"Robert H. Mazur"'
1
Discovery of Aspartame
Autor: Robert H. Mazur
The discovery of the taste of L-aspartyl-L-phenylalanine methyl ester—aspartame—was accidental, as has been true for the discovery of previous novel chemical compounds having a sweet taste. In the early 1960s one of the projects in the Searle res
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0de7bf9127de189463ca7ab61b849875
https://doi.org/10.1201/9781003065289-2
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6
Aspartame‐a sweet surprise
Autor: Robert H. Mazur
Publikováno v: Journal of Toxicology and Environmental Health. 2:243-249
The dipeptide ester L-aspartyl-L-phenylalanine methyl ester (APM) has been found to have a remarkably clean, sucrose-like taste with no off flavor and a potency 150-200 times sucrose. Subsequent work has shown that many alpha-amides of L-aspartic aci
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b469e87122101e0c5adc5118eb1824b1
https://doi.org/10.1080/15287397609529429
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7
Bradykinin analogs containing N.alpha.-methyl amino acids
Autor: Robert H. Mazur, Patricia A. James, John H. Sanner, E. Ann Hallinan, Renata Schulze, David A. Tyner
Publikováno v: Journal of Medicinal Chemistry. 23:758-763
Analogues of bradykinin were synthesized containing single substitutions by N alpha-methyl amino acids in the 1, 4, 5, 5, and 9 positions. [MeArg]Bradykinin possessed 60% of the muscle-contracting activity of the parent compound in a guinea pig ileum
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c957263ac634c89a0295610ae3e8f3
https://doi.org/10.1021/jm00181a012
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10
Small-ring Compounds. XXIII. The Nature of the Intermediates in Carbonium Ion-type Interconversion Reactions of Cyclopropylcarbinyl, Cyclobutyl and Allylcarbinyl Derivatives1a
Autor: Marc S. Silver, John D. Roberts, William N. White, C. C. Lee, Robert H. Mazur, Dorothy A. Semenow
Publikováno v: Journal of the American Chemical Society. 81:4390-4398
Investigation of the extent of isotope-position rearrangement in carbonium ion-type reactions of ^(14)C-labeled cyclopropylcarbinyl derivatives has revealed that the three methylene groups of the starting material achieve a striking degree of equival
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0edd34c76a7e115f355527fc74c0f5a3
https://doi.org/10.1021/ja01525a073
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