Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Robert H. Lemus"'
Autor:
Megumi Tsuchiya, James B. Wiesner, Masami Nakane, Atsushi Nagahisa, Michael C. Matelich, Matthew Allan, Robert H Lemus, Brett C. Bookser, Mark D. Erion, Bheemarao G. Ugarkar
Publikováno v:
Journal of Medicinal Chemistry. 48:7808-7820
4-(Phenylamino)-5-phenyl-7-(5-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine 1 and related compounds known as "diaryltubercidin" analogues are potent inhibitors of adenosine kinase (AK) and are orally active in animal models of pain such as the
Autor:
Edward B. Skibo, Robert H. Lemus
Publikováno v:
The Journal of Organic Chemistry. 57:5649-5660
Pyrimido[4,5-g]quinazolinequinone derivatives were synthesized as anthraquinone-like reductive alkylating agents. Like many naturally-occurring antibiotics, these quinone derivatives are designed to afford an alkylating quinone methide species upon r
Autor:
Michael A. Kerr, Kyriacos C. Nicolaou, Kiyoshi Ikeda, Kouichi Ohe, Jonathan Laird Gross, Robert H. Lemus
Publikováno v:
Angewandte Chemie International Edition in English. 33:781-783
Autor:
Edward B. Skibo, Robert H. Lemus, Rogelio Martinez, Robert T. Dorr, Xiaofen Huang, William Craigo
Publikováno v:
Journal of medicinal chemistry. 45(25)
A series of pyrimidoquinazoline analogues, possessing either 4,5-g or 5,4-g fusion, were studied with respect to cytotoxicity, topoisomerase II inhibitory activity, in vivo activity, and DNA cleavage and DNA−protein cross-linking properties. These
Autor:
Kyriacos C. Nicolaou, Jonathan Laird Gross, Kiyoshi Ikeda, Robert H. Lemus, Kouichi Ohe, Michael A. Kerr
Publikováno v:
Angewandte Chemie. 106:790-791
Publikováno v:
The Journal of Organic Chemistry. 54:3611-3618
Synthese et etude du comportement electrochimique de [tetrahydro halogenomethyl-6 methyl-3] imidazo [4,5-g] quinazolinetriones-4,8,9
Autor:
Robert H. Lemus, Edward B. Skibo
Publikováno v:
The Journal of Organic Chemistry. 53:6099-6105