Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Robert H. Kutner"'
Autor:
Marina Cavazzana, Yves Beuzard, Leila Maouche, Gabor Istvan Veres, Olivier Negre, Emmanuel Payen, Philippe Leboulch, Manfred Schmidt, Beatrix Gillet-Legrand, Anais Paulard, Byoung Y. Ryu, Robert H. Kutner, Annette Deichmann, Mitchell Finer, Christophe Joubert, Francis J. Pierciey, Christof von Kalle, Cynthia C. Bartholomae, Raffaele Fronza, Lauryn Christiansen, Edouard de Dreuzy, Michael Rothe, Celine Courne, Maria Denaro
Publikováno v:
Current Gene Therapy. 15:64-81
A previously published clinical trial demonstrated the benefit of autologous CD34 + cells transduced with a selfinactivating lentiviral vector (HPV569) containing an engineered β-globin gene (β A-T87Q -globin) in a subject with β thalassemia major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffe2176935a083d600347aa8833f6f00
https://doi.org/10.2174/1566523214666141127095336
https://doi.org/10.2174/1566523214666141127095336
Publikováno v:
Journal of Virological Methods. 157:113-121
During the past 12 years, lentiviral vectors have emerged as valuable tools for transgene delivery because of their ability to transduce nondividing cells and their capacity to sustain long-term transgene expression. Despite significant progress, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f25a62db567a106e220da0450d71a9
https://doi.org/10.1016/j.jviromet.2008.11.021
https://doi.org/10.1016/j.jviromet.2008.11.021
Publikováno v:
Nature Protocols. 4:495-505
Over the past decade, lentiviral vectors have emerged as powerful tools for transgene delivery. The use of lentiviral vectors has become commonplace and applications in the fields of neuroscience, hematology, developmental biology, stem cell biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac5d97610a8c22582bae95d0b8c818c
https://doi.org/10.1038/nprot.2009.22
https://doi.org/10.1038/nprot.2009.22
Autor:
David M. Ricks, Martha C. Gómez, Betsy L. Dresser, Robert H. Kutner, Justine I. Lyons, Leslie A. Lyons, C. Dumas, Mark T. Ruhe, Monica Lopez, C. Earle Pope, Jakob Reiser
Publikováno v:
Cloning and Stem Cells. 10:469-484
In the present study, we used the sand cat (Felis margarita) as a somatic cell donor to evaluate whether cryopreservation of donor cells alters viability and epigenetic events in donor cells and affects in vitro and in vivo developmental competence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ed086710b32936706dea3b8039c135
https://doi.org/10.1089/clo.2008.0021
https://doi.org/10.1089/clo.2008.0021
Autor:
Najat Daw, Carl A. Gregory, Darwin J. Prockop, Narae Lee, Scott D. Olson, Odile David, Jacob Reiser, Robert H. Kutner, Edwin M. Horwitz, Angela J. Smolarz
Publikováno v:
British Journal of Cancer
Canonical Wnt signaling is an osteo-inductive signal that promotes bone repair through acceleration of osteogenic differentiation by progenitors. Dkk-1 is a secreted inhibitor of canonical Wnt signaling and thus inhibits osteogenesis. To examine a po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412f30451fc96b2d98be2ecb9ca88b19
http://europepmc.org/articles/PMC2360262
http://europepmc.org/articles/PMC2360262
Autor:
Stephen P. Kantrow, Jakob Reiser, Lili Bao, Vijayendra R. Jaligam, Robert H. Kutner, Xian-Yang Zhang
Publikováno v:
Human Gene Therapy. 15:445-456
The relatively low efficiency of target cell transduction and variations in the stability of transgene expression by retroviral vectors based on the Moloney murine leukemia virus (MoMLV) are major impediments to the use of such vectors in cancer gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ad85296f8eadb8bbb4156eb0325279
https://doi.org/10.1089/10430340460745775
https://doi.org/10.1089/10430340460745775
Autor:
Brian G. Rowan, Robert H. Kutner, Jeffrey M. Gimble, Muralidharan Anbalagan, Ernest S. Chiu, Majdouline Asher, Mei Sheng, Ryan K. Jones, Paul Friedlander, Trivia Frazier, Eduardo A. Lacayo
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89595 (2014)
PLoS ONE
PLoS ONE
Background Fat grafting is used to restore breast defects after surgical resection of breast tumors. Supplementing fat grafts with adipose tissue-derived stromal/stem cells (ASCs) is proposed to improve the regenerative/restorative ability of the gra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8452fcfd4d9e9a1ab85b5c5cf621667f
http://europepmc.org/articles/PMC3938488?pdf=render
http://europepmc.org/articles/PMC3938488?pdf=render
Publikováno v:
Current Protocols in Cell Biology
The use of lentiviral vectors for transgene delivery in vitro and in vivo for applications in neuroscience, hematology, developmental biology, stem cell biology, and transgenesis has become commonplace. Lentiviral vectors provide an attractive tool f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786a2fd05096a5f31b13ab3e19da397a
https://pubmed.ncbi.nlm.nih.gov/21400699
https://pubmed.ncbi.nlm.nih.gov/21400699
Autor:
William B. Klimstra, Agnieszka Bialkowska, Michael P. Marino, Xian-Yang Zhang, Jakob Reiser, Robert H. Kutner
Publikováno v:
Retrovirology, Vol 7, Iss 1, p 3 (2010)
Retrovirology
Retrovirology
Background The ability to efficiently and selectively target gene delivery vectors to specific cell types in vitro and in vivo remains one of the formidable challenges in gene therapy. We pursued two different strategies to target lentiviral vector d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5081e0d40ec12ce887ad6acde0a3cd8a
http://www.retrovirology.com/content/7/1/3
http://www.retrovirology.com/content/7/1/3
Autor:
C.E. Pope, Martha C. Gómez, Betsy L. Dresser, Leslie A. Lyons, Jakob Reiser, Mark T. Ruhe, Justine I. Lyons, David M. Ricks, C. Dumas, Robert H. Kutner
Publikováno v:
Cloning and stem cells. 11(1)
The efficient use of somatic cell nuclear transfer (SCNT), in conjunction with genetic modification of donor cells provides a general means to add or inactivate genes in mammals. This strategy has substantially improved the efficacy of producing gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c688fdcf3bb7f03aaf4d09e097e54713
https://pubmed.ncbi.nlm.nih.gov/19203232
https://pubmed.ncbi.nlm.nih.gov/19203232